Results 11 to 20 of about 23,102 (293)

Multiple functions of microsomal triglyceride transfer protein [PDF]

Nutrition & Metabolism, 2012
Microsomal triglyceride transfer protein (MTP) was first identified as a major cellular protein capable of transferring neutral lipids between membrane vesicles.
Hussain M Mahmood, Rava Paul, Walsh Meghan, Rana Muhammad, Iqbal Jahangir   +4 more
doaj   +2 more sources

Elevation of plasma phospholipid transfer protein in transgenic mice increases VLDL secretion [PDF]

Journal of Lipid Research, 2002
Two lipid transfer proteins are active in human plasma, cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP). Mice by nature do not express CETP.
Jessica Lie, Rini de Crom, Teus van Gent, Rien van Haperen, Leo Scheek, Inge Lankhuizen, Arie van Tol   +6 more
doaj   +2 more sources

Plasma Lipases And Lipid Transfer Proteins Increase Phospholipid But Not Free Cholesterol Transfer From Lipid Emulsion To High Density Lipoproteins [PDF]

, 2015
Background: Plasma lipases and lipid transfer proteins are involved in the generation and speciation of high density lipoproteins. In this study we have examined the influence of plasma lipases and lipid transfer protein activities on the transfer of ...
Quintao E.C.R., Cazita P.M., Harada L.M., Nunes V.S., Oliveira H.C.F., De Faria E.C.   +5 more
core   +3 more sources

A Single‐Dose, Implant‐Based, Trivalent Virus‐like Particle Vaccine against “Cholesterol Checkpoint” Proteins [PDF]

, 2021
Cardiovascular disease is the number one cause of death globally. Lowering cholesterol levels in plasma is the mainstay therapy; however lifelong treatment and adverse effects call for improved therapeutic interventions.
Pokorski, Jonathan K., Steinmetz, Nicole F., Steinmetz, Nicole, Ortega-Rivera, Oscar A., Ortega-Rivera, Oscar, Nicole F. Steinmetz, Oscar A. Ortega‐Rivera, Jonathan K. Pokorski, Pokorski, Jonathan   +8 more
core   +1 more source

The cholesterol-raising diterpenes from coffee beans increase serum lipid transfer protein activity levels in humans [PDF]

, 1997
Cafestol and kahweol–diterpenes present in unfiltered coffee— strongly raise serum VLDL and LDL cholesterol and slightly reduce HDL cholesterol in humans. The mechanism of action is unknown.
de Roos, B, Tol, Aad, de Roos, B., de Jong-Caesar, R., Scheek, L.M., Urgert, R., Scheek, L. M., Gent, T, Caesar, R (Ruth), Gent, T. van, Katan, MB, Roos, B. de, van Tol, A., Jong-Caesar, R. de, van Gent, T., Tol, A. van, Scheek, LM (Leo), Urgert, R, Katan, M.B.; id_orcid, Katan, M.B.   +19 more
core   +1 more source

Arginine-directed glycation and decreased HDL plasma concentration and functionality [PDF]

, 2014
Background/Objectives: Decreased plasma concentration of high-density lipoprotein cholesterol (HDL-C) is a risk factor linked to increased risk of cardiovascular disease (CVD). Decreased anti-atherogenic properties of HDL are also implicated in increased
Rabbani, Naila, Smith, L., Godfrey, L. (Lisa), Thornalley, Paul J., Yamada-Fowler, N. (Naomi)   +4 more
core   +1 more source

Lecithin:cholesterol acyltransferase and cholesteryl ester transfer activity from the isolated perfused rabbit liver.

Journal of Lipid Research, 1984
Lecithin:cholesterol acyltransferase (LCAT) and cholesteryl ester (CE) transfer activity accumulate linearly in the recirculated medium of the isolated perfused rabbit liver.
L De Parscau, P E Fielding
doaj   +1 more source

Intracellular cholesterol transporter StarD4 binds free cholesterol and increases cholesteryl ester formation*

Journal of Lipid Research, 2008
StarD4 protein is a member of the StarD4 subfamily of steroidogenic acute regulatory-related lipid transfer (START) domain proteins that includes StarD5 and StarD6, proteins whose functions remain poorly defined.
Daniel Rodriguez-Agudo, Shunlin Ren, Eric Wong, Dalila Marques, Kaye Redford, Gregorio Gil, Phillip Hylemon, William M. Pandak   +7 more
doaj   +1 more source

Reduction in the concentration and activity of plasma cholesteryl ester transfer protein by alcohol.

Journal of Lipid Research, 1992
Plasma cholesteryl esters, synthesized within high density lipoproteins (HDL), may be transferred from HDL particles to other lipoproteins by plasma cholesteryl ester transfer protein (CETP).
M Hannuksela, YL Marcel, YA Kesäniemi, MJ Savolainen   +3 more
doaj   +1 more source

Biochemical characterization of cholesteryl ester transfer protein inhibitors

Journal of Lipid Research, 2010
Cholesteryl ester transfer protein (CETP) has been identified as a novel target for increasing HDL cholesterol levels. In this report, we describe the biochemical characterization of anacetrapib, a potent inhibitor of CETP.
Mollie Ranalletta, Kathleen K. Bierilo, Ying Chen, Denise Milot, Qing Chen, Elaine Tung, Caroline Houde, Nadine H. Elowe, Margarita Garcia-Calvo, Gene Porter, Suzanne Eveland, Betsy Frantz-Wattley, Mike Kavana, George Addona, Peter Sinclair, Carl Sparrow, Edward A. O'Neill, Ken S. Koblan, Ayesha Sitlani, Brian Hubbard, Timothy S. Fisher   +20 more
doaj   +1 more source