Results 11 to 20 of about 22,985 (252)

Effect of unesterified cholesterol on the activity of cholesteryl ester transfer protein [PDF]

Biochemical Journal, 1994
Cholesteryl ester transfer protein (CETP) catalyses the transfer of cholesteryl ester from high-density lipoprotein to triacylglycerol-rich lipoproteins and the transfer of triacylglycerols in the reverse direction. The activity of CETP has been studied using a continuous fluorescence assay which measures the excimer fluorescence of cholesteryl 1 ...
O V, Rajaram, R Y, Chan, W H, Sawyer
openaire   +2 more sources

Multiple functions of microsomal triglyceride transfer protein

Nutrition & Metabolism, 2012
Microsomal triglyceride transfer protein (MTP) was first identified as a major cellular protein capable of transferring neutral lipids between membrane vesicles.
Hussain M Mahmood, Rava Paul, Walsh Meghan, Rana Muhammad, Iqbal Jahangir   +4 more
doaj   +1 more source

Lecithin:cholesterol acyltransferase and cholesteryl ester transfer activity from the isolated perfused rabbit liver.

Journal of Lipid Research, 1984
Lecithin:cholesterol acyltransferase (LCAT) and cholesteryl ester (CE) transfer activity accumulate linearly in the recirculated medium of the isolated perfused rabbit liver.
L De Parscau, P E Fielding
doaj   +1 more source

Intracellular cholesterol transporter StarD4 binds free cholesterol and increases cholesteryl ester formation*

Journal of Lipid Research, 2008
StarD4 protein is a member of the StarD4 subfamily of steroidogenic acute regulatory-related lipid transfer (START) domain proteins that includes StarD5 and StarD6, proteins whose functions remain poorly defined.
Daniel Rodriguez-Agudo, Shunlin Ren, Eric Wong, Dalila Marques, Kaye Redford, Gregorio Gil, Phillip Hylemon, William M. Pandak   +7 more
doaj   +1 more source

Reduction in the concentration and activity of plasma cholesteryl ester transfer protein by alcohol.

Journal of Lipid Research, 1992
Plasma cholesteryl esters, synthesized within high density lipoproteins (HDL), may be transferred from HDL particles to other lipoproteins by plasma cholesteryl ester transfer protein (CETP).
M Hannuksela, YL Marcel, YA Kesäniemi, MJ Savolainen   +3 more
doaj   +1 more source

Biochemical characterization of cholesteryl ester transfer protein inhibitors

Journal of Lipid Research, 2010
Cholesteryl ester transfer protein (CETP) has been identified as a novel target for increasing HDL cholesterol levels. In this report, we describe the biochemical characterization of anacetrapib, a potent inhibitor of CETP.
Mollie Ranalletta, Kathleen K. Bierilo, Ying Chen, Denise Milot, Qing Chen, Elaine Tung, Caroline Houde, Nadine H. Elowe, Margarita Garcia-Calvo, Gene Porter, Suzanne Eveland, Betsy Frantz-Wattley, Mike Kavana, George Addona, Peter Sinclair, Carl Sparrow, Edward A. O'Neill, Ken S. Koblan, Ayesha Sitlani, Brian Hubbard, Timothy S. Fisher   +20 more
doaj   +1 more source

Cholesteryl esters in lymph chylomicrons: contribution from high density lipoprotein transferred from plasma into intestinal lymph

Journal of Lipid Research, 1993
Most of the cholesterol in intestinal chyle and chylomicrons is derived from plasma. Our aim was to determine how much plasma low density (LDL) and high density (HDL) lipoproteins contribute to the cholesterol in chyle and chylomicrons, and to examine ...
HC Oliveira, K Nilausen, H Meinertz, EC Quintão   +3 more
doaj   +1 more source

Elevation of plasma phospholipid transfer protein in transgenic mice increases VLDL secretion

Journal of Lipid Research, 2002
Two lipid transfer proteins are active in human plasma, cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP). Mice by nature do not express CETP.
Jessica Lie, Rini de Crom, Teus van Gent, Rien van Haperen, Leo Scheek, Inge Lankhuizen, Arie van Tol   +6 more
doaj   +1 more source

Plasma Proteome Profiling of Patients With In-stent Restenosis by Tandem Mass Tag-Based Quantitative Proteomics Approach

Frontiers in Cardiovascular Medicine, 2022
BackgroundDespite the widespread application of new drug-eluting stents, a considerable portion of patients experience in-stent restenosis (ISR). To date, the pathophysiologic mechanisms of ISR remain poorly understood.MethodsIn this study, we collected ...
Jingyuan Hou, Jingyuan Hou, Qiaoting Deng, Qiaoting Deng, Sudong Liu, Sudong Liu, Xiaohong Qiu, Xunwei Deng, Xunwei Deng, Wei Zhong, Zhixiong Zhong, Zhixiong Zhong   +11 more
doaj   +1 more source

Temporal Dynamics of High-Density Lipoprotein Proteome in Diet-Controlled Subjects with Type 2 Diabetes

Biomolecules, 2020
We examined the effect of mild hyperglycemia on high-density lipoprotein (HDL) metabolism and kinetics in diet-controlled subjects with type 2 diabetes (T2D).
Karim G. Kheniser, Abdullah Osme, Chunki Kim, Serguei Ilchenko, Takhar Kasumov, Sangeeta R. Kashyap   +5 more
doaj   +1 more source