Results 11 to 20 of about 24,034 (108)

Revisiting the Lipid–Cancer Axis: PCSK9, ANGPTL3, and CETP as Emerging Biomarkers and Therapeutic Targets in Oncology [PDF]

open access: yesBiomolecules
Cancer remains a major global health challenge, with persistent limitations in early diagnosis, metastatic disease control, and the achievement of durable therapeutic responses with acceptable toxicity.
Dimitris C. Kounatidis   +7 more
doaj   +2 more sources

Changes in High-Density Lipoprotein Cholesterol and Risks of Cardiovascular Events: A from the PICASSO Trial [PDF]

open access: yesJournal of Stroke, 2020
Background and purpose Whether pharmacologically altered high-density lipoprotein cholesterol (HDL-C) affects the risk of cardiovascular events is unknown.
Eun-Jae Lee   +25 more
doaj   +1 more source

Metabolism of PLTP, CETP, and LCAT on multiple HDL sizes using the Orbitrap Fusion Lumos

open access: yesJCI Insight, 2021
Recent in vivo tracer studies demonstrated that targeted mass spectrometry (MS) on the Q Exactive Orbitrap could determine the metabolism of HDL proteins 100s-fold less abundant than apolipoprotein A1 (APOA1).
Sasha A. Singh   +6 more
doaj   +1 more source

Preferential enrichment of large-sized very low density lipoprotein populations with transferred cholesteryl esters.

open access: yesJournal of Lipid Research, 1985
The effect of lipid transfer proteins on the exchange and transfer of cholesteryl esters from rat plasma HDL2 to human very low (VLDL) and low density (LDL) lipoprotein populations was studied.
S Eisenberg
doaj   +1 more source

High-Density Lipoprotein Modifications: A Pathological Consequence or Cause of Disease Progression?

open access: yesBiomedicines, 2020
High-density lipoprotein (HDL) is well-known for its cardioprotective effects, as it possesses anti-inflammatory, anti-oxidative, anti-thrombotic, and cytoprotective properties.
Andrea Bonnin Márquez   +2 more
doaj   +1 more source

The combined effects of cholesteryl ester transfer protein (CETP) TaqIB gene polymorphism and canola, sesame and sesame-canola oils consumption on metabolic response in patients with diabetes and healthy people [PDF]

open access: yesJournal of Cardiovascular and Thoracic Research, 2020
Introduction: Cholesteryl ester transfer protein (CETP) is a key regulating enzyme in the lipid metabolism pathway, and its gene polymorphism may be a candidate for modulating the metabolic responses to dietary intervention.
Nahid Ramezani-Jolfaie   +10 more
doaj   +1 more source

Effect of unesterified cholesterol on the compartmentation of a fluorescent cholesteryl ester in a lipoprotein-like lipid microemulsion.

open access: yesJournal of Lipid Research, 1992
The access of enzymes and lipid transfer proteins to neutral lipids located predominantly in the core compartment of lipoproteins may be determined to some degree by the solubility of the neutral lipids in the surface monolayer of phospholipid.
QT Li, WH Sawyer
doaj   +1 more source

Multiple functions of microsomal triglyceride transfer protein

open access: yesNutrition & Metabolism, 2012
Microsomal triglyceride transfer protein (MTP) was first identified as a major cellular protein capable of transferring neutral lipids between membrane vesicles.
Hussain M Mahmood   +4 more
doaj   +1 more source

Lecithin:cholesterol acyltransferase and cholesteryl ester transfer activity from the isolated perfused rabbit liver.

open access: yesJournal of Lipid Research, 1984
Lecithin:cholesterol acyltransferase (LCAT) and cholesteryl ester (CE) transfer activity accumulate linearly in the recirculated medium of the isolated perfused rabbit liver.
L De Parscau, P E Fielding
doaj   +1 more source

Intracellular cholesterol transporter StarD4 binds free cholesterol and increases cholesteryl ester formation*

open access: yesJournal of Lipid Research, 2008
StarD4 protein is a member of the StarD4 subfamily of steroidogenic acute regulatory-related lipid transfer (START) domain proteins that includes StarD5 and StarD6, proteins whose functions remain poorly defined.
Daniel Rodriguez-Agudo   +7 more
doaj   +1 more source

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