Results 31 to 40 of about 53,010 (291)

Polyphenol alkyl ester inhibits membrane cholesterol domain formation through an antioxidant mechanism based, in nonlinear fashion, on chain length [PDF]

, 2017
Under conditions of oxidative stress, cholesterol aggregates into discrete membrane bilayer domains that precipitate the formation of extracellular crystals, a hallmark feature of the advanced atheroma in cardiovascular disease.
Durand, Erwann, Jacob, Robert F., Mason, R. Preston, Sherratt, Samuel, Villeneuve, Pierre   +4 more
core   +1 more source

Association of cholesteryl ester transfer protein with HDL particles reduces its proteolytic inactivation by mast cell chymase

Journal of Lipid Research, 2008
Human atherosclerotic intima contains mast cells that secrete the neutral protease chymase into the intimal fluid, which also contains HDL-modifying proteins, such as cholesteryl ester transfer protein (CETP), in addition to abundant amounts of nascent ...
Miriam Lee-Rueckert, Riikka Vikstedt, Jari Metso, Matti Jauhiainen, Petri T. Kovanen   +4 more
doaj   +1 more source

Fenofibrate increases HDL-cholesterol by reducing cholesteryl ester transfer protein expression [PDF]

Journal of Lipid Research, 2007
In addition to efficiently decreasing VLDL-triglycerides (TGs), fenofibrate increases HDL-cholesterol levels in humans. We investigated whether the fenofibrate-induced increase in HDL-cholesterol is dependent on the expression of the cholesteryl ester transfer protein (CETP).
Hoogt, C.C. van der, Haan, W. de, Westerterp, M., Hoekstra, M., Dallinga-Thie, G.M., Romijn, J.A., Princen, H.M.G., Jukema, J.W., Havekes, L.M., Rensen, P.C.N.   +9 more
openaire   +4 more sources

Metabolic labelling of cholesteryl glucosides in Helicobacter pylori reveals how the uptake of human lipids enhances bacterial virulence. [PDF]

, 2016
Helicobacter pylori infects approximately half of the human population and is the main cause of various gastric diseases. This pathogen is auxotrophic for cholesterol, which it converts upon uptake to various cholesteryl α-glucoside derivatives ...
Chen, Yet-Ran, Chen, Yi-Chi, Gervay-Hague, Jacquelyn, Huang, Yu-Chen, Ingle, Arun B, Jan, Hau-Ming, Lin, Chun-Hung, Liu, Sheng-Wen, Mong, Kwok-Kong Tony, Shih, Yu-Yin, Tu, Zhijay, Wu, Ming-Shiang   +11 more
core   +1 more source

Decreased postprandial high density lipoprotein cholesterol and apolipoproteins A-I and E in normolipidemic smoking men: relations with lipid transfer proteins and LCAT activities

Journal of Lipid Research, 1998
We have previously reported that normolipidemic smokers are lipid intolerant due to increased responses of triglyceride-rich lipoproteins (TRL) apolipoprotein B-48, triglyceride (TG), and retinyl esters to a mixed meal compared to non-smokers.
N. Mero, A. Van Tol, L.M. Scheek, T. Van Gent, C. Labeur, M. Rosseneu, M-R. Taskinen   +6 more
doaj   +1 more source

Cholesteryl Ester Transfer Protein Expressed in Lecithin Cholesterol Acyltransferase–Deficient Mice [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2002
Objective— Regulation of plasma cholesteryl ester transfer protein (CETP) concentration was studied in lecithin-cholesterol acyltransferase (LCAT)-knockout mice. Methods and Results— LCAT-knockout mice were cross-bred with CETP
Cheng-ai, Wu, Maki, Tsujita, Kuniko, Okumura-Noji, Shinichi, Usui, Hajime, Kakuuchi, Mitsuyo, Okazaki, Shinji, Yokoyama   +6 more
openaire   +2 more sources

Sonic Hedgehog Is a Member of the Hh/DD-Peptidase Family That Spans the Eukaryotic and Bacterial Domains of Life. [PDF]

, 2018
Sonic Hedgehog (Shh) coordinates Zn2+ in a manner that resembles that of peptidases. The ability of Shh to undergo autoproteolytic processing is impaired in mutants that affect the Zn2+ coordination, while mutating residues essential for catalytic ...
Roelink, Henk
core   +3 more sources

Targeted disruption of steroidogenic acute regulatory protein D4 leads to modest weight reduction and minor alterations in lipid metabolism[S]

Journal of Lipid Research, 2010
Steroidogenic acute regulatory protein (StAR)D4 is a member of the StAR related lipid transfer family. Homology comes from the ∼210 amino acid lipid binding domain implicated in intracellular transport, cell signaling, and lipid metabolism.
Joshua J. Riegelhaupt, Marc P. Waase, Jeanne Garbarino, Daniel E. Cruz, Jan L. Breslow   +4 more
doaj   +1 more source

Polymorphisms at the apoB, apoA-I, and cholesteryl ester transfer protein gene loci in patients with gallbladder disease.

Journal of Lipid Research, 1995
Alterations in lipoprotein levels are reported to be related to an increased risk of gallstones. Plasma lipid metabolism is regulated by a number of proteins that are polymorphic in the population.
T Juvonen, M J Savolainen, M I Kairaluoma, L H Lajunen, S E Humphries, Y A Kesäniemi   +5 more
doaj   +1 more source

Effects of dalcetrapib in patients with a recent acute coronary syndrome [PDF]

, 2012
In observational analyses, higher levels of high-density lipoprotein (HDL) cholesterol have been associated with a lower risk of coronary heart disease events.
Abt, Markus, Ballantyne, Christie M., Barter, Philip J., Brumm, Jochen, Chaitman, Bernard R., Colquhoun, David, Holme, Ingar M., Kallend, David, Leiter, Lawrence A., Leitersdorf, Eran, McMurray, John J. V., Mundl, Hardi, Nicholls, Stephen J., Olsson, Anders G., Schwartz, Gregory G., Shah, Prediman K., Tardif, Jean-Claude, The dal-OUTCOMES Investigators, Wright, R. Scott   +18 more
core   +2 more sources