Results 31 to 40 of about 24,034 (108)

Polymorphisms at the apoB, apoA-I, and cholesteryl ester transfer protein gene loci in patients with gallbladder disease.

Journal of Lipid Research, 1995
Alterations in lipoprotein levels are reported to be related to an increased risk of gallstones. Plasma lipid metabolism is regulated by a number of proteins that are polymorphic in the population.
T Juvonen, M J Savolainen, M I Kairaluoma, L H Lajunen, S E Humphries, Y A Kesäniemi   +5 more
doaj   +1 more source

The role of plasma lipid transfer proteins in lipoprotein metabolism and atherogenesis

Journal of Lipid Research, 2009
The plasma lipid transfer proteins promote the exchange of neutral lipids and phospholipids between the plasma lipoproteins. Cholesteryl ester transfer protein (CETP) facilitates the removal of cholesteryl esters from HDL and thus reduces HDL levels ...
David Masson, Xian-Cheng Jiang, Laurent Lagrost, Alan R. Tall   +3 more
doaj   +1 more source

Periodontitis decreases the antiatherogenic potency of high density lipoprotein

Journal of Lipid Research, 2004
Periodontitis, a consequence of persistent bacterial infection and chronic inflammation, has been suggested to predict coronary heart disease (CHD). The aim of this study was to investigate the impact of periodontitis on HDL structure and antiatherogenic
Pirkko J. Pussinen, Matti Jauhiainen, Tiina Vilkuna-Rautiainen, Jouko Sundvall, Marja Vesanen, Kimmo Mattila, Timo Palosuo, Georg Alfthan, Sirkka Asikainen   +8 more
doaj   +1 more source

Preparation and incorporation of probe-labeled apoA-I for fluorescence resonance energy transfer studies of rHDL

Journal of Lipid Research, 2001
Apolipoprotein A-I (apoA-I), the major constituent of HDL, plays an essential role in regulating cholesterol metabolism, acting as the physiological activator of lecithin: cholesterol acyltransferase, which converts cholesterol to cholesterol ester ...
Hui-hua Li, Michael J. Thomas, Wei Pan, Eric Alexander, Michael Samuel, Mary G. Sorci-Thomas   +5 more
doaj   +1 more source

Expression of CETP and of splice variants induces the same level of ER stress despite secretion efficiency differences

Journal of Lipid Research, 2008
The cholesteryl ester transfer protein (CETP) gene has been associated with a variety of phenotypes, including HDL-cholesterol levels and, more sporadically, with cardiovascular disease, obesity, and extreme longevity. Alterations of CETP activity levels
Maruja E. Lira, A. Katrina Loomis, Sara A. Paciga, David B. Lloyd, John F. Thompson   +4 more
doaj   +1 more source

High density lipoprotein receptors, binding proteins, and ligands

Journal of Lipid Research, 1999
Several HDL binding proteins, quite disparate in structure, have recently been cloned and their role in HDL metabolism is currently being assessed. High density lipoprotein binding protein, HBP (vigilin), which lacks a transmembrane domain is responsive ...
Noel H. Fidge
doaj   +1 more source

Resistance of a very low density lipoprotein subpopulation from familial dysbetalipoproteinemia to in vitro lipolytic conversion to the low density lipoprotein density fraction.

Journal of Lipid Research, 1983
In vitro lipolysis of very low density lipoprotein (VLDL) from normolipidemic and familial dysbetalipoproteinemic plasma by purified bovine milk lipoprotein lipase was studied using the combined single vertical spin and vertical autoprofile method of ...
B H Chung, J P Segrest
doaj   +1 more source

Leukocyte-derived hepatic lipase increases HDL and decreases en face aortic atherosclerosis in LDLr−/− mice expressing CETP*s⃞

Journal of Lipid Research, 2008
In addition to hepatic expression, cholesteryl ester transfer protein (CETP) and hepatic lipase (HL) are expressed by human macrophages. The combined actions of these proteins have profound effects on HDL structure and function. It is not known how these
Neil J. Hime, Audrey S. Black, Josh J. Bulgrien, Linda K. Curtiss   +3 more
doaj   +1 more source

Bone marrow-derived HL mitigates bone marrow-derived CETP-mediated decreases in HDL in mice globally deficient in HL and the LDLr

Journal of Lipid Research, 2014
The objective of this study was to determine the combined effects of HL and cholesteryl ester transfer protein (CETP), derived exclusively from bone marrow (BM), on plasma lipids and atherosclerosis in high-fat-fed, atherosclerosis-prone mice.
Neil J. Hime, Audrey S. Black, David J. Bonnet, Linda K. Curtiss   +3 more
doaj   +1 more source

ApoA-II expression in CETP transgenic mice increases VLDL production and impairs VLDL clearance

Journal of Lipid Research, 2001
Apolipoprotein (apo)A-II is a major high density lipoprotein (HDL) protein; however, its role in lipoprotein metabolism is largely unknown. Transgenic (Tg) mice that overexpress human apoA-II present functional lecithin: cholesterol acyltransferase ...
Joan Carles Escolà-Gil, Josep Julve, Àfrica Marzal-Casacuberta, Jordi Ordóñez-Llanos, Francesc González-Sastre, Francisco Blanco-Vaca   +5 more
doaj   +1 more source