Results 31 to 40 of about 23,102 (293)

Targeted disruption of steroidogenic acute regulatory protein D4 leads to modest weight reduction and minor alterations in lipid metabolism[S]

Journal of Lipid Research, 2010
Steroidogenic acute regulatory protein (StAR)D4 is a member of the StAR related lipid transfer family. Homology comes from the ∼210 amino acid lipid binding domain implicated in intracellular transport, cell signaling, and lipid metabolism.
Joshua J. Riegelhaupt, Marc P. Waase, Jeanne Garbarino, Daniel E. Cruz, Jan L. Breslow   +4 more
doaj   +1 more source

Cholesteryl Ester Transfer Protein Inhibition [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2006
Chemicals / CAS: 2 methylpropanethioic acid s [2 [1 (2 ethylbutyl)cyclohexylcarboxamido]phenyl] ester, 211513-37-0; atorvastatin, 134523-00-5, 134523-03-8; nicotinic acid, 54-86-4, 59-67-6; torcetrapib, 262352-17-0; Carrier Proteins; CETP protein, human; Cholesterol Ester Transfer Proteins; Cholesterol Esters; Cholesterol, HDL; Glycoproteins ...
Rensen, P.C.N., Havekes, L.M.
openaire   +2 more sources

Polymorphisms at the apoB, apoA-I, and cholesteryl ester transfer protein gene loci in patients with gallbladder disease.

Journal of Lipid Research, 1995
Alterations in lipoprotein levels are reported to be related to an increased risk of gallstones. Plasma lipid metabolism is regulated by a number of proteins that are polymorphic in the population.
T Juvonen, M J Savolainen, M I Kairaluoma, L H Lajunen, S E Humphries, Y A Kesäniemi   +5 more
doaj   +1 more source

The role of plasma lipid transfer proteins in lipoprotein metabolism and atherogenesis

Journal of Lipid Research, 2009
The plasma lipid transfer proteins promote the exchange of neutral lipids and phospholipids between the plasma lipoproteins. Cholesteryl ester transfer protein (CETP) facilitates the removal of cholesteryl esters from HDL and thus reduces HDL levels ...
David Masson, Xian-Cheng Jiang, Laurent Lagrost, Alan R. Tall   +3 more
doaj   +1 more source

The roles of the carboxyl-terminal regions of phospholipid transfer protein (PLTP) and cholesteryl ester transfer protein (CETP) in lipid transfer.

, 2002
In human plasma, there are two lipid transfer proteins that play major roles in lipoprotein metabolism and reverse cholesterol transport. Cholesterol ester transfer protein (CETP) transfers neutral lipids, and is responsible for all of the plasma ...
Walter, Stephanie.
core   +2 more sources

Periodontitis decreases the antiatherogenic potency of high density lipoprotein

Journal of Lipid Research, 2004
Periodontitis, a consequence of persistent bacterial infection and chronic inflammation, has been suggested to predict coronary heart disease (CHD). The aim of this study was to investigate the impact of periodontitis on HDL structure and antiatherogenic
Pirkko J. Pussinen, Matti Jauhiainen, Tiina Vilkuna-Rautiainen, Jouko Sundvall, Marja Vesanen, Kimmo Mattila, Timo Palosuo, Georg Alfthan, Sirkka Asikainen   +8 more
doaj   +1 more source

Evaluation of phospholipid transfer protein and cholesteryl ester transfer protein as contributors to the generation of pre beta-high-density lipoproteins [PDF]

, 2001
High-density lipoproteins (HDLs) are considered anti-atherogenic because they mediate peripheral cell cholesterol transport to the liver for excretion and degradation.
Gent, T. (Teus) van, Tol, Aad, van Haperen, Rien, Jauhiainen, M., Crom, Rini, Jansen, H, Jansen, H. (Hans), Haperen, M.J. (Rien) van, Gent, T, Lie, JT (Jessica), Scheek, L. (Leo), Ehnholm, C, Scheek, LM (Leo), Lie, J. (Jessica), Ehnholm, C. (Christian), Tol, A. (Arie) van, Crom, M.P.G. (Rini) de, Jauhiainen, M   +17 more
core   +1 more source

Structure-based mechanism and inhibition of cholesteryl ester transfer protein

, 2023
Purpose of ReviewCholesteryl ester transfer proteins (CETP) regulate plasma cholesterol levels by transferring cholesteryl esters (CEs) among lipoproteins.
Liu, Jianfang, Wang, Jianjun, Zhang, Meng, Ren, Gang, Xue, Han   +4 more
core   +1 more source

Preparation and incorporation of probe-labeled apoA-I for fluorescence resonance energy transfer studies of rHDL

Journal of Lipid Research, 2001
Apolipoprotein A-I (apoA-I), the major constituent of HDL, plays an essential role in regulating cholesterol metabolism, acting as the physiological activator of lecithin: cholesterol acyltransferase, which converts cholesterol to cholesterol ester ...
Hui-hua Li, Michael J. Thomas, Wei Pan, Eric Alexander, Michael Samuel, Mary G. Sorci-Thomas   +5 more
doaj   +1 more source

Expression of CETP and of splice variants induces the same level of ER stress despite secretion efficiency differences

Journal of Lipid Research, 2008
The cholesteryl ester transfer protein (CETP) gene has been associated with a variety of phenotypes, including HDL-cholesterol levels and, more sporadically, with cardiovascular disease, obesity, and extreme longevity. Alterations of CETP activity levels
Maruja E. Lira, A. Katrina Loomis, Sara A. Paciga, David B. Lloyd, John F. Thompson   +4 more
doaj   +1 more source