Results 161 to 170 of about 18,706 (235)

Mito-TEMPO improves survival rates in <i>npc1</i>-knockout zebrafish by reducing oxidative stress and enhancing mitophagy via Sod2. [PDF]

Sci Adv
Zhao W, Hu X, Wang R, Zhang H, Zhou M, Cao H.   +5 more
europepmc   +1 more source

Tripterine Liposome Exerts Antitumor and Immunomodulatory Effects in Pancreatic Ductal Adenocarcinoma

MedComm, Volume 7, Issue 10, October 2026.
Tripterine liposome (TP‐lipo) exerts anti‐pancreatic ductal adenocarcinoma (PDAC) effects through direct suppression of tumor cells and modulation of the tumor microenvironment (TME). TP‐lipo induces apoptosis and inhibits the clonogenicity, migration, and invasion of KPC cells in vitro.
Lirui Tang, Yi Lin, Xueqin Jiang, Xiaohe Tian, Giuseppe Battaglia, Yuquan Wei, Wenshuang Wu, Xuemei He, Xiawei Wei   +8 more
wiley   +1 more source

Macrophage-mediated nutrient recycling: evolutionary insights into the metabolic role of professional phagocytes. [PDF]

Front Immunol
Krejčová G, Bajgar A.
europepmc   +1 more source

Mucosal‐Associated Invariant T Cells in Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao, Feng‐Mi Ou, Dan Liang, Yang Gao, Qing‐Qing Li, Yi‐Qun Kuang   +5 more
wiley   +1 more source

The interplay between lipid metabolism, cancer progression and anti-cancer immunity. [PDF]

Exp Mol Med
Koh CH, Lee Y, Kim IK, Chung Y.
europepmc   +1 more source

Transplantation of Elderly Human Gut Microbiota Into Pigs Reprograms Intestinal Barrier Function, Plasma Metabolome, and Gut Mucosal Transcriptomic Landscape

Aging Cell, Volume 25, Issue 10, October 2026.
Elderly human donor microbiota disrupts intestinal barrier integrity and reshapes host metabolic and mucosal transcriptional profiles in human microbiota‐associated pigs. Integrated multi‐omics analyses identify coordinated microbial, metabolic, and host alterations associated with age‐related intestinal decline.
Jiaxin Wang, Lingyu Li, Lihua Mei, Zhining Tang, Baorui Liao, Qianye Zhao, Yuzeng Wang, Qingyao Fu, Liu Ren, Zhian Zhai, Yifei Xu, Aoyu Yang, Shuai Duan, Zhengyuan Zhai, Yanling Hao, Yalin Zhou, Yajun Xu, Ying Yang, Zhenlong Wu, Yun Ji   +19 more
wiley   +1 more source

Hepatocyte Growth Hormone Receptor Ablation Is Associated With Aging Phenotypes and Hepatic Mitochondrial Dysfunction

Aging Cell, Volume 25, Issue 10, October 2026.
Hepatocyte‐specific GHR ablation is associated with hepatic and age‐related pathologies, triggering adipose‐liver crosstalk via elevated circulating GH and subsequent CD36‐dependent hepatic steatosis. This loss impairs STAT5b phosphorylation and enhances PPARγ nuclear activation, upregulating Pdk4 and Cd36 to drive mitochondrial dysfunction and ectopic
Kangkang Yang, Yuli Jian, Fusheng Pang, Ming Ying, Qian Yang, Nian Liu, Shujing Wang, Yingjie Wu   +7 more
wiley   +1 more source

Dietary shrimp by‐product meal as a fishmeal replacement: Effects on growth performance and acute stress responses in juvenile Pacific white shrimp (Penaeus vannamei)

Journal of the World Aquaculture Society, Volume 57, Issue 5, October 2026.
Abstract Sustainable aquafeed development requires alternative protein sources that reduce dependence on fishmeal without compromising shrimp performance. This study evaluated shrimp by‐product meal (SBM) as a fishmeal replacer in juvenile Pacific white shrimp (Penaeus vannamei) and assessed their responses to acute air exposure stress.
Deni Aulia, Hyuncheol Jeon, Haham Kim, Md Hashibur Rahman, Hsu Lae Yee Toe, Junhyeok Hur, Haeun Jang, Sanghyun Park, Jaeun Kim, Jinho Heo, Eunjae Jung, I Nyoman Radiarta, Seunghyung Lee   +12 more
wiley   +1 more source

Cholesterol in Mitochondrial Diseases-Friend or Foe? [PDF]

Int J Mol Sci
Taylor M, Halicki M, Chazot P.
europepmc   +1 more source

Distinct Plasma Proteomic Signatures Distinguish MASLD From Non‐Steatotic Individuals but Not From MetALD

Liver International, Volume 46, Issue 10, October 2026.
ABSTRACT Background and Aims Metabolic dysfunction associated steatotic liver disease (MASLD) is the most prevalent liver disease, yet accurate early detection remains challenging. A particular diagnostic obstacle is distinguishing MASLD from metabolic dysfunction and alcohol‐related liver disease (MetALD), currently defined using clinically informed ...
Niharika Jakhar, Tobias Seibel, Maria Mironova, Corinna Meeßen, Jan Clusmann, Yazhou Chen, Thriveni B. Raju, Paul‐Henry Koop, Juliette E. Pearce, Ivan G. Costa, Thomas Stiehl, Andreas Schuppert, Kai Markus Schneider, Yaron Rotman, Carolin V. Schneider   +14 more
wiley   +1 more source