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Function of cholesteryl ester transfer protein in reverse cholesterol transport.
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 1993 openaire +1 more source
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Cholesteryl ester transfer proteins, reverse cholesterol transport, and atherosclerosis
Current Opinion in Lipidology, 1995Plasma cholesteryl ester transfer protein plays a central role in lipoprotein metabolism by exchanging cholesteryl esters with triglycerides. Human genetic deficiency is associated with increased HDL-cholesterol levels, whereas cholesteryl ester transfer protein overexpression in transgenic mice results in decreased HDL-cholesterol.
C, Bruce, A R, Tall
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Effects of an Inhibitor of Cholesteryl Ester Transfer Protein on HDL Cholesterol
New England Journal of Medicine, 2004Decreased high-density lipoprotein (HDL) cholesterol levels constitute a major risk factor for coronary heart disease; however, there are no therapies that substantially raise HDL cholesterol levels. Inhibition of cholesteryl ester transfer protein (CETP) has been proposed as a strategy to raise HDL cholesterol levels.We conducted a single-blind ...
Margaret E, Brousseau +7 more
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Cholesterol Ester Transfer Protein: A Molecule with Three Faces?
Critical Reviews in Clinical Laboratory Sciences, 1998The pathogenesis of atherosclerosis continues to be a focus of intensive study. One of the more recent players in the atherosclerosis drama is cholesterol ester transfer protein (CETP). CETP is primarily involved in lipid transfer between lipoproteins, for example, from high-density lipoproteins (HDL) to apo B-containing lipoproteins, but CETP has also
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HDL and Cholesterol Ester Transfer Protein (CETP)
2022Cholesterol ester transfer protein (CETP) is important clinically and is one of the major targets in cardiovascular disease studies. With high conformational flexibility, its tunnel structure allows unforced movement of high-density lipoproteins (HDLs), VLDLs, and LDLs.
Siying, Deng +2 more
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Cholesterol ester transfer protein (CETP) and atherosclerosis
Drug Discovery Today: Therapeutic Strategies, 2007Atherosclerotic cardiovascular disease continues to be a major healthcare problem in developed as well as developing nations. Although adoption of a healthy lifestyle coupled with use of lipid modifying and antithrombotic agents significantly reduces the risk of major cardiovascular events, a significant residual burden remains.
Donna Polk, P.K. Shah
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Cholesterol Ester Transfer Protein in Children on Peritoneal Dialysis
Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, 2004Objectives To examine whether cholesterol ester transfer protein (CETP) activity and mass contribute to dyslipidemia in children on peritoneal dialysis (PD), and to determine whether CETP activity or mass is responsible for severer hyperlipidemia in smaller (younger) patients.
Yuriko, Tanaka +5 more
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