Results 261 to 270 of about 53,010 (291)

Lecithin: Cholesterol Acyl Transferase, Cholesterol Ester Exchange/Transfer Protein, and Lipoprotein Particles

1989
More than 80% of the cholesteryl esters (CE) found in human plasma derive from the reaction of lecithin: cholesterol acyl transferase (LCAT). Since the content of CE in plasma high positively correlates with the incidence of atherosclerosis and myocardial infarction, there has been in the past and still is great interest in investigation of the enzymes
G. M. Kostner, E. Steyrer
openaire   +1 more source

Differential regulation of cholesterol homeostasis in transgenic mice expressing human cholesterol ester transfer protein.

Canadian journal of physiology and pharmacology, 2007
We investigated whether expression of cholesterol ester transfer protein (CETP) in mice alters the regulation of cholesterol metabolism. Transgenic mice expressing human CETP (CETP-TG) and nontransgenic littermates (non-TG) were fed either a monounsaturated fatty acid (MUFA) or a saturated fatty acid (SFA)-rich diet in the presence or absence of ...
Alka, Agarwal-Mawal, Cathy M, Murray, Suresh, Belkhode, Sukhinder Kaur, Cheema   +3 more
openaire   +4 more sources

[HDL and reverse cholesterol transport. Role of cholesterol ester transfer protein].

Comptes rendus des seances de la Societe de biologie et de ses filiales, 1993
As most of peripheral cells are not able to catabolize cholesterol, the transport of cholesterol excess from peripheral tissues back to the liver, namely "reverse cholesterol transport", is the only way by which cholesterol homeostasis is maintained in vivo.
L, Lagrost, P, Gambert
openaire   +1 more source

[Cholesterol ester transfer protein (CETP)].

Nihon rinsho. Japanese journal of clinical medicine, 1995
Plasma CETP plays an important role in the reverse cholesterol transport system in conjunction with lecithin:cholesterol acyltransferase (LCAT). CETP mediates transfer of cholesteryl ester from HDL to apo B containing lipoproteins and also mediates transfer of triglyceride from VLDL and IDL to HDL.
openaire   +1 more source

The Pharmacology and Off-Target Effects of Some Cholesterol Ester Transfer Protein Inhibitors

The American Journal of Cardiology, 2009
Inhibitors of cholesterol ester transfer protein (CETP) have the capacity to increase plasma high-density lipoprotein cholesterol to unprecedented levels. Still, hopes that CETP inhibition could reduce atherosclerosis were dented when the clinical development of one such inhibitor, torcetrapib, was halted because of an unexpected finding of increased ...
Vergeer, Menno, Stroes, Erik S. G.
openaire   +2 more sources

The cholesterol ester transfer protein inhibitor, anacetrapib

Current Opinion in Lipidology, 2011
Ishwarlal, Jialal, Jaspreet, Kaur
openaire   +3 more sources

Cholesterol Ester Transfer Protein, Characterization of Monoclonal Antibodies against the Human Antigen

1988
Early work by Rehnborg and Nichols (1) showed that upon incubation of normolipemic plasma, cholesteryl ester (CE) concentration increased in VLDL, LDL and HDL whereas triglycerides (TG) concentration decreased in VLDL and increased in LDL and HDL. These experiments (1,2) were the first to document CE transfer between lipoproteins but the concept was ...
Y L, Marcel, R W, Milne, P K, Weech, H, Czarnecka, C B, Hesler, A R, Tall   +5 more
openaire   +2 more sources

[Cholesterol ester transfer protein. A major player in cholesterol metabolism].

Ugeskrift for laeger, 1999
Plasma cholesterol transfer protein (P-CETP) plays a central role in cholesterol metabolism by pronroting transfer of cholesteryl esters from high density lipoprotein (HDL) to very low density lipoproteins in exchange for triglycerides. The CETP-reaction may hereby be a critical factor in reverse cholesterol transport, i.e., the transfer of cholesterol
openaire   +1 more source

Effects of Cholesterol Ester Transfer Protein Inhibition on HDL Metabolism

2010
Cholesteryl ester transfer protein (CETP) facilitates the transfer of cholesteryl ester from high lipoproteins (HDLs) to triglyceride-rich lipoproteins (TRLs) in exchange for triglyceride. CETP forms a channel or tube between HDL and TRL allowing for this exchange.
openaire   +1 more source

[Detection of cholesterol ester transfer protein in semen of infertile patients].

Zhonghua nan ke xue = National journal of andrology, 2003
To detect the cholesterol ester transfer protein (CETP) levels in semen of infertile patients and evaluate the correlation between CETP in semial plasma and infertility.One hundred and sixty-three infertile patients and fifteen fertile males were selected randomly.
Yong-Xin, Liu, Pei-Yuan, Zhu, Jun-Jun, Wang, Jun, Mo, Yu-Feng, Huang   +4 more
openaire   +1 more source