Results 171 to 180 of about 30,189 (224)

Cholesterol Sensing, Trafficking, and Esterification

Annual Review of Cell and Developmental Biology, 2006
Mammalian cells acquire cholesterol from low-density lipoprotein (LDL) and from endogenous biosynthesis. The roles of the Niemann-Pick type C1 protein in mediating the endosomal transport of LDL-derived cholesterol and endogenously synthesized cholesterol are discussed.
Ta-Yuan, Chang, Catherine C Y, Chang, Nobutaka, Ohgami, Yoshio, Yamauchi   +3 more
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Blood groups and plasma cholesterol esterification

Cardiovascular Research, 1973
Plasma total, esterified and non-esterified cholesterol, and ABO and Lewis blood groups were determined in blood samples obtained from 767 university students. Though mean total cholestrol concentration was greater in those of group A than in those of the remaining ABO groups, there were no differences in the proportions of esterified and non ...
E J, Wakley, M J, Langman
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Esterification of cholesterol by canine adrenal homogenates

Archives of Biochemistry and Biophysics, 1962
Abstract Tracer amounts of cholesterol-4-C11 were incorporated into sterol esters and adrenal steroids by whole homogenates of dog adrenal glands. The esterification reaction was stimulated by addition of ATP, CoA, DPN and a TPNH-generating system (TPN and G6P).
R E, DAILEY, L, SWELL, C R, TREADWELL
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Plasma Cholesterol Esterification in Vivo in Man

Scandinavian Journal of Clinical and Laboratory Investigation, 1974
The turnover of plasma-esterified cholesterol can be measured in vivo after injection of radiomevalonate. Values obtained in vivo are similar to measurements made in vitro. Esterification of cholesterol occurs mainly in plasma: when cholesterol synthesis is stimulated, newly formed cholesterol enters plasma predominantly unesterified.
P J, Nestel, N E, Miller, P, Clifton-Bligh   +2 more
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Plasma cholesterol esterification rate in hyperlipoproteinaemia: Relation to cholesterol elimination

Scandinavian Journal of Clinical and Laboratory Investigation, 1988
The present study was undertaken to determine the relationship between plasma lecithin: cholesterol acyl transfer (LCAT) rate and cholesterol and bile acid turnover in hyperlipidaemia. Nineteen healthy controls, 19 patients with hyperlipoproteinaemia (HLP) type IIa and 12 patients with HLP type IV were studied under standardized dietary conditions ...
B, Angelin, K, Einarsson, B, Leijd, L, Wallentin   +3 more
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The Enzymology of Cholesterol Esterification

Scandinavian Journal of Clinical and Laboratory Investigation, 1974
Formation of cholesteryl esters are catalyzed by several different enzymes, the most important are acyl-CoA: cholesterol acyltransferase, lecithin: cholesterol acyltransferase, and cholesterol ester hydrolase. Because the substrates of these enzymes are mostly water-insoluble and bound to biomembranes, and because the products are transferred to other ...
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Cholesterol esterification in rat-liver cell sap

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1967
Abstract The existence of a cholesterol-est erifying enzyme was investigated with sap from liver cells. After subfractionation of liver homogenates, cholesterol esterification was checked with particulate and cell sap fractions and compared with the activity in plasma. Cholesterol was esterified on incubation with cell sap.
M, Akiyama, O, Minari, T, Sakagami
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Esterification of cholesterol in rat liver microsomes

Archives of Biochemistry and Biophysics, 1964
Washed rat liver microsomes esterify cholesterol in the presence of added ATP and CoA; net synthesis of cholesterol esters was demonstrated. The optimum pH of the reaction was between 6.8 and 7.2; the effects of time and concentration of substrate were investigated.
L, SWELL, M D, LAW, C R, TREADWELL
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Lipid Composition and Cholesterol Esterification in Lymph

Scandinavian Journal of Clinical and Laboratory Investigation, 1974
The different lipoprotein classes are present in cardiac lymph in mutual proportions similar to those in serum. This indicates that even the largest lipoproteins are filtered through the capillary membranes to a remarkably high extent. Free and esterified cholesterol and phospholipids are present in cardiac lymph in concentrations about 30–40 per cent ...
K T, Stokke, N B, Fjeld, T H, Kluge, S, Skrede   +3 more
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Hepatotoxicity and plasma cholesterol esterification by rats

Archives of Biochemistry and Biophysics, 1969
Abstract Plasma lecithin:cholesterol acyltransferase activity in vitro was measured in rats treated with ethionine or CCl 4 . The purpose of this study is to find the effect of liver injury on the one hand, and the relationship of the activity to the plasma lipid concentration and composition on the other hand.
M, Sugano, K, Hori, M, Wada
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