Journal of Lipid Research, 1983 The regulation of rabbit intestinal acyl CoA:cholesterol acyltransferase (ACAT) by 25-hydroxycholesterol was studied. 25-Hydroxycholesterol significantly increased jejunal microsomal ACAT activity.
F J Field, S N Mathur
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Liver Transplantation to Provide Low-Density-Lipoprotein Receptors and Lower Plasma Cholesterol in a Child with Homozygous Familial Hypercholesterolemia [PDF]
, 1984 A six-year-old girl with severe hypercholesterolemia and atherosclerosis had two defective genes at the low-density-lipoprotein (LDL) receptor locus, as determined by biochemical studies of cultured fibroblasts.
Cummings +9 more
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The Distal Pathway of Lipoprotein-induced Cholesterol Esterification, but Not Sphingomyelinase-induced Cholesterol Esterification, Is Energy-dependent [PDF]
Journal of Biological Chemistry, 1996 The stimulation of the intracellular cholesterol esterification pathway by atherogenic lipoproteins in macrophages is a key step in the development of atheroma foam cells. The esterification pathway can also be stimulated by hydrolysis of cell-surface sphingomyelin by the enzyme sphingomyelinase (SMase).
P J, Skiba +4 more
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Feedback modulation of cholesterol metabolism by the lipid-responsive non-coding RNA LeXis. [PDF]
, 2016 Liver X receptors (LXRs) are transcriptional regulators of cellular and systemic cholesterol homeostasis. Under conditions of excess cholesterol, LXR activation induces the expression of several genes involved in cholesterol efflux, facilitates ...
Casero, David +13 more
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Journal of Lipid Research, 1989 The response of parameters of plasma cholesterol metabolism was studied in baboons adapted either to a low-fat, low-cholesterol diet or a high-fat, high-cholesterol diet. Animals adapted to the low-fat diet responded to a single low-fat or high-fat meal,
P E Fielding, E M Jackson, C J Fielding
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Chromosomal location of a gene that controls sterol esterification in Triticum aestivum L. [PDF]
, 1974 A previously described D genome locus (Pln) that controls sterol esterification in the wheat kernel has been assigned to the short arm of chromosome 7 D by comparison of the steryl ester phenotype of euploid kernels of Triticum aestivum variety Chinese ...
Bennett +17 more
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Journal of Lipid Research, 2009 Several studies indicate that cholesterol esterification is deregulated in cancers. The present study aimed to characterize the role of cholesterol esterification in proliferation and invasion of two tumor cells expressing an activated cholecystokinin 2 ...
Michael R. Paillasse +5 more
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Cholesterol Esterification by Adrenal Homogenates.
Experimental Biology and Medicine, 1963 SummaryCholesterol-esterifying activity was demonstrated in homogenates of rat, rabbit and guinea pig adrenals.
C. Longcope, R. H. Williams
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Mechanisms of dysregulation of low-density lipoprotein receptor expression in vascular smooth muscle cells by inflammatory cytokines [PDF]
, 2006 Objective - Although inflammation is a recognized feature of atherosclerosis, the impact of inflammation on cellular cholesterol homeostasis is unclear.
Ma, KL +6 more
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Interleukin-4 augments acetylated LDL-induced cholesterol esterification in macrophages
Journal of Lipid Research, 2000 : Activated subpopulations of lymphocytes and mast cells have been detected in atherosclerotic lesions. Interleukin-4 (IL-4) is a prominent cytokine released during activation of both cell types and its transcripts have been detected in both human and ...
Joseph A. Cornicelli +4 more
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