Results 51 to 60 of about 30,189 (224)

Movement of cholesterol in vitro in rat blood and quantitation of the exchange of free cholesterol between plasma and erythrocytes

Journal of Lipid Research, 1972
After administration of [4-14C]cholesterol to rats, blood was obtained and incubated for 6 hr or less. Incubation resulted in a net loss of erythrocyte cholesterol and, simultaneously, in an increase of esterified cholesterol in plasma and a-lipoproteins.
F. d'Hollander, F. Chevallier
doaj   +1 more source

Bile acids: Lipase-catalyzed synthesis of new hyodeoxycholic acid derivatives [PDF]

, 2018
In this work we present an efficient, environmentally friendly approach to the synthesis of a series of hyodeoxycholic acid derivatives applying Biocatalysis.
Baldessari, Alicia, Chanquia, Santiago Nahuel, Garcia Liñares, Guadalupe Eugenia, Ripani, Erika Aldana   +3 more
core   +1 more source

High‐Content SRS Imaging Unveils Altered Cholesterol Metabolism in Ovarian Cancers Under CAR‐T Treatment

Advanced Science, EarlyView.
High‐content Stimulated Raman Scattering (SRS) Imaging reveals that ovarian cancer cells surviving Chimeric Antigen Receptor (CAR) ‐T cell challenge exhibit increased cholesterol esterification. Pharmacological inhibition of this pathway with Avasimibe significantly enhances CAR‐T induced killing of ovarian cancer cells by reducing cancer cell ...
Chinmayee V. Prabhu Dessai, Zhuoying Huang, Haonan Lin, Guangrui Ding, Hongjian He, Menna Siddiqui, Meng Zhang, Wilson Wong, Ji‐Xin Cheng   +8 more
wiley   +1 more source

The sterol substrate specificity of acyl CoA: :cholesterol acyltransferase from rat liver.

Journal of Lipid Research, 1982
Rat liver microsomes were incubated with various sterols suspended in Triton WR-1339, and the extent of esterification of these sterols by acyl CoA:cholesterol acyltransferase was determined.
D M Tavani, W R Nes, J T Billheimer
doaj   +1 more source

Stimulation of bioprocesses by ultrasound [PDF]

, 2011
Ultrasound (US) has become a ubiquitous technological process in a large variety of scientific disciplines. However, little information exists on the use of ultrasound to enhance biological processes and/or processing and consequently this paper provides
Akunna, Joseph C., Bennett, Jason, Bremner, David H., Kwiatkowska, Barbara, Walker, Graeme M.   +4 more
core   +3 more sources

ACSL1‐Dependent Microglial Lipoimmunometabolic Reprogramming Underlies Cognitive Deficits in Alcohol Use Disorder

Advanced Science, EarlyView.
This study reveals that chronic alcohol exposure selectively upregulates ACSL1 expression in prefrontal cortical microglia, driving lipid metabolism reprogramming and lipid droplet accumulation, which activates the NLRP3 inflammasome and sustains neuroinflammation. To reverse this process, a dual‐targeted lipid nanoparticle, siACSL1@LNP‐MR, is designed
Liang Hao, Xing‐Rui Cao, Bai‐Qiang Li, Fu‐Ying Zhao, Jia‐Mei Wang, Rui‐Kang Gao, Zhi‐Peng Cao, Zhen‐Xian Du, Hua‐Qin Wang   +8 more
wiley   +1 more source

Alcohol consumption stimulates early steps in reverse cholesterol transport

Journal of Lipid Research, 2001
Alcohol consumption is associated with increased HDL cholesterol levels, which may indicate stimulated reverse cholesterol transport. The mechanism is, however, not known.
M.S. van der Gaag, A. van Tol, S.H.F. Vermunt, L.M. Scheek, G. Schaafsma, H.F.J. Hendriks   +5 more
doaj   +1 more source

Autotrophic and Heterotrophic Growth Conditions Modify Biomolecole Production in the Microalga Galdieria sulphuraria (Cyanidiophyceae, Rhodophyta) [PDF]

, 2020
Algae have multiple similarities with fungi, with both belonging to the Thallophyte, a polyphyletic group of non-mobile organisms grouped together on the basis of similar characteristics, but not sharing a common ancestor.
Barone, R., Carraturo, F., D'Elia, L., De Napoli, L., Gambino, E., Guida, M., Lorito, M., Marra, R., Mayol, L., Paolucci, M., Pollio, A., Vinale, F., Volpe, M. G., Woo, S. L.   +13 more
core   +1 more source

Hepatotoxicity of Nonesterified Fatty Acids to Dairy Cows: Pathophysiological Mechanisms and Prospective Solutions

Animal Research and One Health, EarlyView.
Unregulated inflammation increases non‐esterified fatty acids (NEFAs), and triggers multi‐pathway hepatocyte damage including oxidative stress, mitochondrial dysfunction, and metabolic disorders in dairy cows. ABSTRACT Circulating concentrations of nonesterified fatty acids (NEFAs) are elevated due to lipid mobilization from adipose tissue in ...
Siqing Mao, Yuan Tian, Dan Li, Lei Tian, Hang Yu, Ziling Liu, Xin Gao, Yanqiong Wen, Fachun Wan, Zuo Wang, Weijun Shen, Xinwei Li, Lei Liu   +12 more
wiley   +1 more source

Fatty acids differentially regulate hepatic cholesteryl ester formation and incorporation into lipoproteins in the liver of the mouse

Journal of Lipid Research, 2002
These experiments tested the hypothesis that fatty acids (FAs) that drive cholesterol esterification also enhance sterol secretion and were undertaken using a mouse model where lipoprotein-cholesterol output by the liver could be assessed in vivo.
Chonglun Xie, Laura A. Woollett, Stephen D. Turley, John M. Dietschy   +3 more
doaj   +1 more source