Results 161 to 170 of about 349,779 (262)

CYP46A1 activation by low-dose efavirenz uncovers the link between brain cholesterol metabolism, energetics, and vasculature. [PDF]

Biomed Pharmacother
Mast N, Bederman I, El-Darzi N, Pikuleva IA.   +3 more
europepmc   +1 more source

The EXPLAIN Study: Exploring Arthrogryposis Multiplex Congenita in Adults in Norway — A Description of Demographic, Medical, and Neurological Findings

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Arthrogryposis Multiplex Congenita (AMC) encompasses several hundred conditions with diverse genetic, pathophysiological, and clinical origins. The overarching EXPLAIN study explores underlying causes and implications of AMC and represents the largest clinical cohort of adults with AMC reported to date.
My Vuong Hermansen, Kristin Ørstavik, Unni Steen, Mathias Toft, Cathrine Brunborg, Lena Lande Wekre   +5 more
wiley   +1 more source

<i>Enteromorpha prolifera</i> Polysaccharide Alleviates Type 2 Diabetes via the Gut Microbiota-Liver Axis to Modulate Cholesterol Metabolism. [PDF]

Food Sci Nutr
Zhu L, Wen X, Zhu W, Hu X, Xu Y, Peng X.
europepmc   +1 more source

CHOLESTEROL METABOLISM IN THE DOG

Journal of Biological Chemistry, 1956
L L, ABELL, E H, MOSBACH, F E, KENDALL
openaire   +2 more sources

Molecular mechanism of ischemic postconditioning in promoting diabetic ischemic brain injury repair via the microRNA‐34a–BDNF–SIX3 signaling axis

Animal Models and Experimental Medicine, EarlyView.
Diabetes combined with ischemic stroke (DMIS) exacerbates brain infarct size and neuronal damage compared to nondiabetic ischemic stroke (IS). This study reveals that microRNA‐34a (miR‐34a) plays a key role in DMIS pathogenesis: miR‐34a directly targets and suppresses brain‐derived neurotrophic factor (BDNF) and Sine oculis homeobox 3 (SIX3), promoting
Ling Zhao, Chunlan Zou, Junxian Li, Yang Yang, Yuanyuan Han, Tingyu Ke   +5 more
wiley   +1 more source

STAT1 signaling controls cholesterol metabolism in epithelial cells and RSV-induced syncytia formation. [PDF]

Npj Viruses
Agac A, Ludlow M, Knittler MC, Osterhaus ADME, Rimmelzwaan GF, Meineke R.   +5 more
europepmc   +1 more source

Research progress on biomarkers of traumatic brain injury

Animal Models and Experimental Medicine, EarlyView.
Traumatic brain injury: From primary insult to secondary neuroinflammation and degeneration. Abstract Traumatic brain injury (TBI) is a common disorder of the nervous system and has become a leading cause of death and disability worldwide, imposing a substantial burden on patients and their social circles. Its main symptoms include dyskinesia, language
Xuting Shen, Si Cheng, Shuyi Chen, Mengyue Wang, Tangying Li, Weicheng Xu, Yifan Zhang, Ping Yuan, Lei Shi   +8 more
wiley   +1 more source

Paeoniflorin Modulates TREM-1/NF-κB/LXRα/ABCG1 Pathway to Improve Cholesterol Metabolism and Inflammation in Hyperlipidemic Rat. [PDF]

Int J Mol Sci
Yang Y, Li X, Tang DL, Li B, Wu SJ, Cao HX, Zong WJ, Zhang HM.   +7 more
europepmc   +1 more source

A high‐fat diet with vitamin D and propylthiouracil produces a pro‐atherogenic phenotype in rats

Animal Models and Experimental Medicine, EarlyView.
Male Sprague–Dawley rats received a cholesterol‐rich high‐fat diet supplemented with vitamin D and propylthiouracil for 11 weeks. The model induced dyslipidemia (increased total cholesterol/low‐density lipoprotein, decreased triglycerides), inflammation (increased interleukin‐6 and serum amyloid A), hypercalcemia, and reduced circulating endothelial ...
Angélique Lewies, Vitaris Kodogo, Johannes Frederik Wentzel, Francis Edwin Smit   +3 more
wiley   +1 more source

Role of Oxysterol-Binding Protein Family in Cholesterol Metabolism and Cancer Progression: A Review. [PDF]

Med Sci Monit
Wu Y, Lv X, Yang J, Liu S, Chen Y, Yuan Z, Wang X.   +6 more
europepmc   +1 more source