Results 271 to 280 of about 588,707 (355)

Effect of Indigestible Dextrin on Cholesterol Metabolism in Rat.

, 1991
Shigeru WAKABAYASHI, Mitsuko Satouchi, Y Nogami, Kazuhiro Ohkuma, Akira Matsuoka   +4 more
openalex   +2 more sources

Post‐Translational Regulation of CD8+ T Cell Fate and Dysfunction in Tumor Immunity

Advanced Science, EarlyView.
This review delineates how post‐translational modifications (PTMs) function as a central regulatory interface governing CD8+ T cell activation, differentiation, persistence, and exhaustion in antitumor immunity. By integrating antigenic, metabolic, and microenvironmental cues, diverse PTM programs coordinate transcriptional and chromatin states that ...
Zihao Zhou, Xu Chen, Nina Li, Meiyan Zou, Yunfan Lin, Pei Lin, Weiyao Feng, Xinyuan Zhao, Li Cui   +8 more
wiley   +1 more source

Contrasting Effects of Clozapine and Risperidone on Cholesterol Metabolism, Synaptic Proteins, and Transcriptional Regulation in Human LUHMES Neurons. [PDF]

Mol Neurobiol
Rybczyński P, Cacala R, Cepil Z, Fic E, Romanska W, Marczak L, Pustelny K, Kedracka-Krok S.   +7 more
europepmc   +1 more source

Enzyme‐Activated MRI for In Vivo Glucose Imaging via a Biodegradable Chromium Nanoprobe

Advanced Science, EarlyView.
Enzyme‐activated MRI (eaMRI) using a biodegradable CrGOx@Lip nanoprobe enables glucose‐specific imaging in vivo. GOx catalyzes glucose oxidation, triggering in situ formation of paramagnetic chromium gluconate and amplifying T1. This radiation‐free strategy maps tumor glucose uptake via the Warburg‐effect, quantifies hepatic glucose accumulation in ...
Yan Xu, Weitao Yang, Yanjing Yun, Hui Wang, Zhuoyao Wu, Youyi Yu, Bingbo Zhang   +6 more
wiley   +1 more source

Effect of cholesterol metabolism on hepatolithiasis. [PDF]

World J Gastroenterol
Zheng L, Ye ZY, Ma JJ.
europepmc   +1 more source

Deep Learning‐Assisted Coherent Raman Scattering Microscopy

Advanced Intelligent Discovery, EarlyView.
The analytical capabilities of coherent Raman scattering microscopy are augmented through deep learning integration. This synergistic paradigm improves fundamental performance via denoising, deconvolution, and hyperspectral unmixing. Concurrently, it enhances downstream image analysis including subcellular localization, virtual staining, and clinical ...
Jianlin Liu, Rujia Liu, Xinyan Zhang, Xun Chen, Shuhua Yue   +4 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism. [PDF]

Mol Oncol
Vaquié AM, Shah DR, Brechbühl EES, McNicholas M, Xu Z, Stockley JH, Morcom L, Gold Diaz D, Girdler GC, Seear RV, Balmus G, Ratan RR, Bulstrode H, Nathan JA, Pathania M, Brindle KM, Rowitch DH.   +16 more
europepmc   +1 more source

Toward Predictable Nanomedicine: Current Forecasting Frameworks for Nanoparticle–Biology Interactions

Advanced Intelligent Discovery, EarlyView.
Predictive models successfully screen nanoparticles for toxicity and cellular uptake. Yet, complex biological dynamics and sparse, nonstandardized data limit their accuracy. The field urgently needs integrated artificial intelligence/machine learning, systems biology, and open‐access data protocols to bridge the gap between materials science and safe ...
Mariya L. Ivanova, Michael Nicholls, Nicola Russo, Gueorgui Mihaylov, Konstantin Nikolic   +4 more
wiley   +1 more source

Cholesterol Metabolism Regulated Nanoliposome Ameliorates Chemo/Photothermal Therapy Reversing CD8⁺ T Cell Exhaustion. [PDF]

Exploration (Beijing)
Xue P, Bai T, Zhuang H, All AH, Yan S, Zeng X.   +5 more
europepmc   +1 more source

The Association of Sleeping Duration and Sleep Problems With All‐Cause Mortality Among a Cohort of Industrial Workers Followed Up for 36 Years

American Journal of Industrial Medicine, EarlyView.
ABSTRACT Background Sleep duration is a well‐established factor associated with all‐cause mortality and cardiovascular mortality. Poor sleep quality was also suggested to affect all‐cause mortality risk among adults. The Cardiovascular Occupational Risk Factor determination in Israel Study (CORDIS) is a prospective cohort study of industrial workers ...
Gil Harari, Anat Gesser‐Edelsburg
wiley   +1 more source