Results 71 to 80 of about 586,832 (295)
Arthritis Care &Research, EarlyView.Objective Body mass index (BMI), glomerular filtration rate (GFR), and pretreatment urate levels have been reported to influence the urate‐lowering response to allopurinol. We investigated whether the fractional excretion of uric acid (FEUA) also modulates this response and relates to oxypurinol concentrations.
Pascal Richette +13 more
wiley +1 more source
Journal of Lipid Research, 2011 Cholesteryl ester transfer protein (CETP) catalyses the exchange of cholesteryl ester and triglyceride between HDL and apoB containing lipoprotein particles.
Guoqing Cao +10 more
doaj +1 more source
The cholesterol-raising diterpenes from coffee beans increase serum lipid transfer protein activity levels in humans [PDF]
, 1997 Cafestol and kahweol–diterpenes present in unfiltered coffee— strongly raise serum VLDL and LDL cholesterol and slightly reduce HDL cholesterol in humans. The mechanism of action is unknown.
Gent, T. van +6 more
core +3 more sources
Arthritis Care &Research, Accepted Article.Objective To investigate the association between rheumatoid arthritis (RA) and coronary artery calcium (CAC) prevalence, incidence, and progression over four years in adults without prior cardiovascular disease. Methods A case‐cohort study within ELSA‐Brasil included 585 participants (86 RA, 499 controls). Longitudinal analyses were restricted to those
Patrícia Fonseca Estrada +7 more
wiley +1 more source
Advanced Functional Materials, EarlyView.We have developed DEX/GM, an all‐natural, personalizable hybrid vaccine designed by coating dendritic cell‐derived exosomes (DEX) onto tumor cell membranes (GM) for sustained prophylaxis against glioblastoma (GBM). ABSTRACT Glioblastoma (GBM), one of the most aggressive and lethal brain tumors, remains incurable with a poor clinical prognosis.
Shanshan Li +6 more
wiley +1 more source
Cholesterol metabolism and immune response
生物医学转化Cholesterol and its various metabolites are essential components of cell and organelle membranes, playing crucial roles in regulating membrane mobility, permeability, lipid raft formation, and signal transduction.
Wang Shuang +3 more
doaj +1 more source
Deficient Cholesterol Esterification in Plasma of apoc2 Knockout Zebrafish and Familial Chylomicronemia Patients. [PDF]
, 2017 Hypertriglyceridemia is an independent risk factor for cardiovascular disease. Apolipoprotein C-II (APOC2) is an obligatory cofactor for lipoprotein lipase (LPL), the major enzyme catalyzing plasma triglyceride hydrolysis.
Gaudet, Daniel +2 more
core +1 more source
Hepatocarcinogenesis and Ceramide/Cholesterol Metabolism [PDF]
Anti-Cancer Agents in Medicinal Chemistry, 2012 Sphingolipids (SLs) and cholesterol are critical structural components of membrane bilayers. Although recent evidence has revealed an emerging role of both lipids in signaling pathways, their contribution to cancer development and treatment has been largely overlooked. Sphingolipids comprise a family of bioactive lipids with divergent roles in numerous
Morales, Albert +4 more
openaire +3 more sources
Nanothermometry in Living Cells: Physical Limits, Conceptual and Material Challenges
Advanced Functional Materials, EarlyView.Heat and temperature are fundamental to life. When nanothermometers began probing regions as small as a living cell, they triggered controversial claims of large intracellular temperature gradients. We review physical constraints energy‐conservation, entropy production, thermodynamic fluctuations, and molecular dynamics.
Taras Plakhotnik
wiley +1 more source