Results 121 to 130 of about 254,209 (239)
Urotensin II receptor deletion mitigates high‐fat diet‐induced kidney injury and renal lipid remodeling. Male wild‐type (WT) and urotensin II receptor–knockout (UT KO) mice were fed a high‐fat diet (HFD; 60% kcal from fat) for 33 weeks. In cultured mouse podocytes, urotensin II (UII)–UT signaling enhanced transient receptor potential canonical 6 (TRPC6)
Praghalathan Kanthakumar +1 more
wiley +1 more source
Integrative Analysis Uncover the Effects and Multi‐Omics Features of Thigh Muscle Fat Infiltration
Thigh muscle fat infiltration (TMFI), estimated from MRI, is associated with increased mortality and diseases affecting multiple organ systems and mediates the effects of lifestyle factors on health. Multi‐omics analyses delineate the genetic, cellular, transcriptional, proteomic, and metabolic architecture of TMFI.
Yiwei Zhang +12 more
wiley +1 more source
Glucocorticoids Stimulate Cholesteryl Ester Formation in Human Smooth Muscle Cells
The aim of the present study was to investigate the effect of synthetic glucocorticoid dexamethasone (Dex) on cholesterol esterification in cultured human smooth muscle cells (SMC). In labeled SMC, Dex stimulated the esterification of [ 3
Yuri A. Shakhov +4 more
core +1 more source
Abstract Background Angiopoietin‐like protein 3 (ANGPTL3) is a key circulating regulator of triglyceride metabolism and a promising pharmacological target. The physiological consequences of profound ANGPTL3 deficiency can be explored in individuals with inherited loss‐of‐function (LOF) variants, who show reduced lifetime risk of atherosclerotic ...
Marcello Arca +16 more
wiley +1 more source
Autophagy in MASLD: A Metabolic and Precision Medicine Perspective
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) is the most common chronic liver condition worldwide and a major contributor to cirrhosis and hepatocellular carcinoma (HCC). While metabolic triggers such as obesity and insulin resistance are key drivers of MASLD, growing evidence has identified defects in intracellular quality
Alessandra Cazzaniga +4 more
wiley +1 more source
Lymph chylomicrons labeled with 14C-cholesterol and plasma very low and intermediate density lipoproteins (d less than 1.019) labeled with 3H-cholesterol were injected simultaneously into recipient cholesterol-fed rabbits.
D B Zilversmit, S Stender
core +1 more source
Lipoprotein-proteoglycan complexes from human atherosclerotic lesions were studied to determine their ability to stimulate cholesteryl ester accumulation in human monocytes/macrophages.
B Radhakrishnamurthy +3 more
core +1 more source
These studies were undertaken to determine the kinetic characteristics of high density lipoprotein (HDL) apo AI and cholesteryl ester transport in the hamster in vivo.
Laura A. Woollett, David K. Spady
core
Endurance training increased HDL cholesteryl ester metabolism in rats
We studied the effects of endurance training on the metabolism of high-density lipoprotein (HDL, 1.063 less than density less than 1.15 kg/l) cholesteryl ester and proteins in rats fed a cholesterol-rich (1%) semipurified diet. The HDL were labeled with
T. P. White, A. H. Terpstra, A. E. Pels
core +1 more source
Effects of cholesteryl ester transfer protein TAQ1B polymorphism in renal transplant patients
Background. Dyslipidemia is an important complication in renal transplant patients. Cholesteryl ester transfer protein (CETP) mediates the exchange of cholesteryl ester between high density lipoproteins and low density lipoproteins. The aim of this study
YILMAZ, Hülya +5 more
core +1 more source

