Results 181 to 190 of about 254,209 (239)

Obicetrapib exhibits favorable physiochemical and pharmacokinetic properties compared to previous cholesteryl ester transfer protein inhibitors: An integrated summary of results from non-human primate studies and clinical trials. [PDF]

Pharmacol Res Perspect
Nicholls SJ, Nelson AJ, Kastelein JJP, Ditmarsch M, Hsieh A, Johnson J, Curcio D, Kling D, Kirkpatrick CF, Davidson MH.   +9 more
europepmc   +1 more source

VHL mutation drives human clear cell renal cell carcinoma progression through PI3K/AKT-dependent cholesteryl ester accumulation. [PDF]

EBioMedicine
Zhang S, Fang T, He Y, Feng W, Yu Z, Zheng Y, Zhang C, Hu S, Liu Z, Liu J, Yu J, Zhang H, He A, Gong Y, He Z, Yang K, Xi Z, Yu W, Zhou L, Yao L, Yue S.   +20 more
europepmc   +1 more source

Apolipoprotein E knockout, but not cholesteryl ester transfer protein (CETP)-associated high-density lipoprotein cholesterol (HDL-C) lowering, exacerbates muscle wasting in dysferlin-null mice. [PDF]

Lipids Health Dis
Sun Z, White Z, Theret M, Bernatchez P.
europepmc   +1 more source

Scavenger Receptor BI Deficiency in Mice Is Associated With Plasma Ceramide and Sphingomyelin Accumulation and a Reduced Cholesteryl Ester Fatty Acid Length and Unsaturation Degree. [PDF]

J Lipid Atheroscler
Hoekstra M, Zhang Z, Lindenburg PW, Van Eck M.   +3 more
europepmc   +1 more source

Large and Cholesteryl Ester-Rich High-Density Lipoproteins in Cholesteryl Ester Transfer Protein

Large and Cholesteryl Ester-Rich High-Density Lipoproteins in Cholesteryl Ester Transfer Protein
openaire   +1 more source

Calcium Antagonists and Cholesteryl Ester Metabolism in Macrophages

Journal of Cardiovascular Pharmacology, 1991
Experimental data indicate that calcium antagonists modify cellular lipid metabolism in the arterial wall as part of their antiatherosclerotic action observed in animal models. In the present study, we investigated the effect of verapamil, nifedipine, and lacidipine (a new dihydropyridine derivative) on cholesteryl ester metabolism in cultured mouse ...
Bernini F, Bellosta S, Didoni G, Fumagalli R.   +3 more
openaire   +5 more sources

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Bound Phospholipids Assist Cholesteryl Ester Transfer in the Cholesteryl Ester Transfer Protein

Journal of Chemical Information and Modeling, 2023
Cholesteryl ester transfer protein (CETP) is a plasma glycoprotein that assists the transfer of cholesteryl esters (CEs) from antiatherogenic high-density lipoproteins (HDLs) to proatherogenic low-density lipoproteins (LDLs), initiating cholesterol plaques in the arteries.
Amrutha Keshavamurthy, Prasanna D. Revanasiddappa, Sneha M. Dixit, Gandasi R. Priyanka   +3 more
openaire   +3 more sources

Cholesteryl Ester Transfer Protein Activity Enhances Plasma Cholesteryl Ester Formation

Arteriosclerosis, Thrombosis, and Vascular Biology, 1997
The plasma cholesteryl ester transfer protein (CETP) promotes the removal of HDL cholesteryl esters and is thought to stimulate reverse cholesterol transport (RCT). However, mechanisms by which CETP may stimulate RCT are poorly understood.
Akihiro Inazu, Alan Tall, Oliveira Hcf   +2 more
exaly   +2 more sources

The activity of cholesteryl ester transfer protein is decreased in hypothyroidism: a possible contribution to alterations in high‐density lipoproteins

European Journal of Clinical Investigation, 1990
The activity of cholesteryl ester transfer protein is instrumental in the distribution of cholesteryl ester between lipoproteins in plasma. We measured the activity of cholesteryl ester transfer protein in plasma, designated cholesteryl ester transfer ...
J E Groener, R P Dullaart
exaly   +2 more sources

Cholesteryl esters in malignancy

Clinica Chimica Acta, 2005
Cholesteryl esters, formed by the esterification of cholesterol with long-chain fatty acids, on one hand, are the means by which cholesterol is transported through the blood by lipoproteins, on the other, the way cholesterol itself can be accumulated in the cells.
MR TOSI, V TUGNOLI
openaire   +4 more sources