Torcetrapib impairs endothelial function in hypertension [PDF]
, 2017 Aims A marked increase in HDL notwithstanding, the cholesterol ester transfer protein (CETP) inhibitor torcetrapib was associated with an increase in all-cause mortality in the ILLUMINATE trial.
Besler, Christian +8 more
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Cytosolic lipid trafficking proteins STARD4 and STARD5 modulate hepatic neutral lipid metabolism: implications for diabetic dyslipidaemia and steatosis [PDF]
, 2015 Dolan, Sharron +2 more
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Developmental Expression of Elements of Hepatic Cholesterol Metabolism In The Rat [PDF]
, 1995 The expression of several key enzymes and receptors of rat hepatic cholesterol metabolism was studied during development. Among major findings were: acyl coenzyme A:cholesterol acyltransferase, the cholesteryl ester hydrolases, cholesterol-7 alpha ...
Erickson, S. K. +2 more
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Intracellular cholesterol transporters and modulation of hepatic lipid metabolism: implications for diabetic dyslipidaemia and steatosis [PDF]
, 2014 Caridis, Anna-Maria +3 more
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Vascular effects and safety of dalcetrapib in patients with or at risk of coronary heart disease: the dal-VESSEL randomized clinical trial [PDF]
, 2017 Aims High-density lipoprotein cholesterol (HDL-C) is inversely associated with cardiovascular (CV) events and thus an attractive therapeutic target. However, in spite of marked elevations in HDL-C, the first cholesterol transport protein (CETP) inhibitor
Deanfield, John E. +7 more
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Association of the polymorphisms of the cholesteryl ester transfer protein gene with coronary artery disease: a meta-analysis. [PDF]
Front Cardiovasc Med, 2023 Zhang R, Xie Q, Xiao P.
europepmc +1 more source
Msp1 Polymorphism of Cholesteryl Ester Transfer Protein in Patients with Hypercholesterolemia
پزشکی بالینی ابن سینا, 2013 Introduction & Objective: It has been shown that there is a correlation between cholesterol con-centration and coronary heart disease (CHD). Cholesteryl ester transfer protein (CETP) plays a central role in lipoproteins metabolism and it has been ...
Taghi Hassanzadeh +4 more
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Serum amyloid A augments the atherogenic effects of cholesteryl ester transfer protein. [PDF]
J Lipid Res, 2023 Ji A +6 more
europepmc +1 more source
Anacetrapib: potential for the prevention and treatment of coronary heart disease
Research Reports in Clinical Cardiology, 2013 Dylan L Steen,1 Amit V Khera,2 Christopher P Cannon1 1TIMI Study Group, Cardiovascular Division, 2Department of Medicine, Brigham and Women’s Hospital, Boston, MA, USA Abstract: Despite major advances in cardiovascular care in recent decades ...
Steen DL, Khera AV, Cannon CP
doaj
Evaluation of phospholipid transfer protein and cholesteryl ester transfer protein as contributors to the generation of pre beta-high-density lipoproteins [PDF]
, 2001 High-density lipoproteins (HDLs) are considered anti-atherogenic because they mediate peripheral cell cholesterol transport to the liver for excretion and degradation.
Crom, M.P.G. (Rini) de +8 more
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