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Anacetrapib, a cholesteryl ester transfer protein inhibitor

Expert Opinion on Investigational Drugs, 2011
Inhibition of cholesteryl ester transfer protein (CETP) has the ability to increase high-density lipoprotein (HDL)-cholesterol levels and potentially reduce cardiovascular risk. The first CETP inhibitor, torcetrapib, was discontinued due to off-target effects resulting in increased mortality.
Amanda J, Hooper, John R, Burnett
openaire   +2 more sources

Dalcetrapib, a cholesteryl ester transfer protein modulator

Expert Opinion on Investigational Drugs, 2012
Cholesteryl ester transfer protein (CETP) plays an important role in reverse cholesterol transport by transferring cholesteryl esters from high-density lipoprotein (HDL) to the apolipoprotein B-containing lipoproteins. Inhibition of CETP is a target to increase HDL-cholesterol and potentially reduce atherosclerosis.
Amanda J, Hooper, John R, Burnett
openaire   +2 more sources

Cholesteryl Ester Transfer Protein Reaction between Plasma Lipoproteins

Journal of Biochemistry, 1998
The rate of the non-directional transfer of cholesteryl ester and triglyceride by human cholesteryl ester transfer protein (CETP) was measured between human plasma lipoproteins by monitoring fluorescence spectrum of pyrene-labeled lipid. The transfer rates between high density lipoproteins (HDLs) and between low density lipoproteins (LDLs) were both ...
L A, Main   +3 more
openaire   +2 more sources

Molecular genetics of plasma cholesteryl ester transfer protein

Current Opinion in Lipidology, 1997
Plasma cholesteryl ester transfer protein facilitates the transfer of cholesteryl ester from HDL to apolipoprotein B-containing lipoproteins, and is a key protein in the reverse cholesterol transport system. The importance of plasma cholesteryl ester transfer protein in lipoprotein metabolism was highlighted by the discovery of deficient individuals ...
S, Yamashita   +6 more
openaire   +2 more sources

Cholesteryl Ester Transfer Protein and Atherogenesis

Annals of the New York Academy of Sciences, 1997
A, Tall   +6 more
openaire   +2 more sources

Cholesteryl Ester Transfer Protein Inhibition: A Dysfunctional Endothelium

Journal of Cardiovascular Pharmacology, 2010
Westerterp, Marit   +2 more
openaire   +2 more sources

The contemporary management of cancers of the sinonasal tract in adults

Ca-A Cancer Journal for Clinicians, 2023
Rajat Thawani
exaly  

Cholesteryl Ester Transfer Protein and Lipid Metabolism and Cardiovascular Diseases.

Advances in Experimental Medicine and Biology, 2020
H. Oliveira, Helena F. Raposo
semanticscholar   +1 more source

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