Associations among serum insulin, calprotectin, and C-reactive protein concentrations in Miniature Schnauzers with idiopathic hyperlipidemia before and after feeding an ultra-low-fat diet. [PDF]
Abstract Background Miniature Schnauzers (MS) commonly have idiopathic hypertriglyceridemia (HTGL), which is associated with insulin resistance (IR) and a subclinical inflammatory phenotype. Objectives Determine the association between indicators of IR and inflammatory biomarkers in MS with and without HTGL and identify how indicators of IR are ...
Xenoulis PG +6 more
europepmc +2 more sources
Primary biliary cholangitis presenting as acute ischemic stroke: A rare association. [PDF]
Primary biliary cholangitis is associated with hyperlipidemia, but studies show that the condition does not increase cardiovascular risks. The case presents acute ischemic stroke with no underlying risk factors and subsequent new diagnosis of primary biliary cholangitis, which can suggest possible association between primary biliary cholangitis and ...
Park B +3 more
europepmc +2 more sources
Monocyte to high-density lipoprotein ratio predicts clinical outcomes after acute ischemic stroke or transient ischemic attack. [PDF]
Higher monocyte to high‐density lipoprotein ratio was associated with a high risk of all‐cause death and poor functional outcome at 3 months and 1 year in patients with ischemic or TIA. Elevated MHR can independently predict all‐cause death and poor functional outcome in patients with ischemic stroke or TIA.
Xu Q +12 more
europepmc +2 more sources
Aims SAR247799 is a G‐protein‐biased sphingosine‐1 phosphate receptor‐1 (S1P1) agonist designed to activate endothelial S1P1 and provide endothelial‐protective properties, while limiting S1P1 desensitization and consequent lymphocyte‐count reduction associated with higher doses.
Luc Bergougnan +22 more
wiley +1 more source
Lipoprotein(a) [Lp(a)], aka “Lp little a”, was discovered in the 1960s in the lab of the Norwegian physician Kåre Berg. Since then, we have greatly improved our knowledge of lipids and cardiovascular disease (CVD). Lp(a) is an enigmatic class of lipoprotein that is exclusively formed in the liver and comprises two main components, a single copy of ...
Motasim M. Jawi +3 more
wiley +1 more source
Oral Protein Therapy for the Future - Transport of Glycolipid-Modified Proteins: Vision or Fiction? [PDF]
The reliable and early diagnosis of common complex multifactorial diseases depends on the individual determination of all (or as many as possible) polymorphisms of each susceptibility gene together with amount and type of the corresponding gene products ...
Mueller, Guenter
core +1 more source
The Association between HDL-C and Subclinical Atherosclerosis Depends on CETP Plasma Concentration:Insights from the IMPROVE Study [PDF]
The impact of cholesteryl ester transfer protein (CETP) on atherosclerosis is highly debated. This study aimed to investigate the associations between plasma CETP or CETP genotypes and carotid intima-media thickness (cIMT) and the influence of high ...
Alessio Ravani +21 more
core +2 more sources
Consumption of Artificially-Sweetened Soft Drinks in Pregnancy and Risk of Child Asthma and Allergic Rhinitis [PDF]
Background: Past evidence has suggested a role of artificial sweeteners in allergic disease; yet, the evidence has been inconsistent and unclear. Objective: To examine relation of intake of artificially-sweetened beverages during pregnancy with child ...
Halldorsson, Thorhallur I. +3 more
core +7 more sources
Large-scale gene-centric analysis identifies novel variants for coronary artery disease [PDF]
Coronary artery disease (CAD) has a significant genetic contribution that is incompletely characterized. To complement genome-wide association (GWA) studies, we conducted a large and systematic candidate gene study of CAD susceptibility, including ...
Strawbridge, Rona +1 more
core +1 more source
Preventive Effect of Naringin on Metabolic Syndrome and Its Mechanism of Action: A Systematic Review
Background. Metabolic syndrome (MetS), which consists of cluster of conditions, hypertension, hyperlipidemia, hyperglycemia, and visceral obesity, is affecting population worldwide. Studies have shown that plant derived flavonoids have the ability to alleviate MetS.
Sivanesan Raja Kumar +5 more
wiley +1 more source

