A genome-wide linkage and association analysis of imputed insertions and deletions with cardiometabolic phenotypes in Mexican Americans: The Insulin Resistance Atherosclerosis Family Study. [PDF]
Genet Epidemiol, 2017 Gao C +9 more
europepmc +2 more sources
The cholesterol-raising diterpenes from coffee beans increase serum lipid transfer protein activity levels in humans [PDF]
, 1997 Cafestol and kahweol–diterpenes present in unfiltered coffee— strongly raise serum VLDL and LDL cholesterol and slightly reduce HDL cholesterol in humans. The mechanism of action is unknown.
Gent, T. van +6 more
core +3 more sources
Arteriosclerosis, Thrombosis and Vascular Biology, 2020 Supplemental Digital Content is available in the text. Objective: HDL (high-density lipoprotein) role in atherosclerosis is controversial. Clinical trials with CETP (cholesterylester transfer protein)-inhibitors have not provided benefit.
S. Ben-Aicha +10 more
semanticscholar +1 more source
Alterations of the mitochondrial proteome caused by the absence of mitochondrial DNA: A proteomic view [PDF]
Electrophoresis 27 (04/2006) 1574-83, 2006 The proper functioning of mitochondria requires that both the mitochondrial and the nuclear genome are functional. To investigate the importance of the mitochondrial genome, which encodes only 13 subunits of the respiratory complexes, the mitochondrial rRNAs and a few tRNAs, we performed a comparative study on the 143B cell line and on its Rho-0 ...
arxiv +1 more source
Fabrication of electronically conductive protein-heme nanowires for power harvesting [PDF]
Small, 2024, 2311661, 2023 Electronically conductive protein-based materials could enable the creation of bioelectronic components and devices from sustainable and nontoxic materials, while also being well-suited to interface with biological systems, such as living cells, for biosensor applications.
arxiv +1 more source
Heat and Mass Transfer, 2023 Single steps in cleaning a fouled heat exchanger surface eventually determine the cleaning kinetic and thus the overall performance of a cleaning process.
H. Wiese +3 more
semanticscholar +1 more source
Vasculoprotective properties of plasma lipoproteins from brown bears (Ursus arctos) [PDF]
, 2021 Plasma cholesterol and triglyceride (TG) levels are twice as high in hibernating brown bears (Ursus arctos) than healthy humans. Yet, bears display no signs of early stage atherosclerosis development when adult.
Aasa, Ulrika +14 more
core +2 more sources
Preventive Effect of Naringin on Metabolic Syndrome and Its Mechanism of Action: A Systematic Review
Evidence-Based Complementary and Alternative Medicine, Volume 2019, Issue 1, 2019., 2019 Background. Metabolic syndrome (MetS), which consists of cluster of conditions, hypertension, hyperlipidemia, hyperglycemia, and visceral obesity, is affecting population worldwide. Studies have shown that plant derived flavonoids have the ability to alleviate MetS.
Sivanesan Raja Kumar +5 more
wiley +1 more source
Learning Geometrically Disentangled Representations of Protein Folding Simulations [PDF]
arXiv, 2022 Massive molecular simulations of drug-target proteins have been used as a tool to understand disease mechanism and develop therapeutics. This work focuses on learning a generative neural network on a structural ensemble of a drug-target protein, e.g. SARS-CoV-2 Spike protein, obtained from computationally expensive molecular simulations.
arxiv
Charge Transfer Database for Bio-molecule Tight Binding Model Derived from Thousands of Proteins [PDF]
ACS Omega, 2018, 3 (4), pp 4094, 2018 The anisotropic feature of charge transfer reactions in realistic proteins cannot be ignored, due to the highly complex chemical structure of bio-molecules. In this work, we have performed the first large-scale quantitative assessment of charge transfer preference in protein complexes by calculating the charge transfer couplings in all 20*20 possible ...
arxiv +1 more source