Results 31 to 40 of about 266,324 (188)

Mapping novel genetic loci associated with female liver weight variations using Collaborative Cross mice

Animal Models and Experimental Medicine, Volume 1, Issue 3, Page 212-220, September 2018., 2018
Abstract Background Liver weight is a complex trait, controlled by polygenic factors and differs within populations. Dissecting the genetic architecture underlying these variations will facilitate the search for key role candidate genes involved directly in the hepatomegaly process and indirectly involved in related diseases etiology.
Hanifa J. Abu‐Toamih Atamni, Maya Botzman, Richard Mott, Irit Gat‐Viks, Fuad A. Iraqi   +4 more
wiley   +1 more source

Vascular Function in Chronic Non-Communicable Diseases [PDF]

, 2022
Chronic non-communicable diseases (CNCDs) are one of the major causes of mortality and morbidity worldwide [...]
Noce, Annalisa, Tesauro, Manfredi
core   +1 more source

Parameter adaptations during phenotype transitions in progressive diseases [PDF]

, 2011
Background The study of phenotype transitions is important to understand progressive diseases, e.g., diabetes mellitus, metabolic syndrome, and cardiovascular diseases.
Hilbers, Peter AJ, Tiemann, Christian A, van Riel, Natal AW, Vanlier, Joep   +3 more
core   +4 more sources

HOMA-IR and non-HDL-C as predictors of high cholesteryl ester transfer protein activity in patients at risk for type 2 diabetes [PDF]

, 2023
Background and aims: Metabolic syndrome (MS) and type 2 diabetes are highly associated with an abnormal lipoprotein profile, which may be generated and accentuated by high cholesteryl ester transfer protein (CETP) activity.
Brites, Fernando, Coniglio, R. I., Ferraris, R., Gomez Rosso, Leonardo, Malaspina, M. M., Meroño, Tomás, Montiel, H,, Otero, J. C., Salgueiro, A. M., Schreier, L.   +9 more
core   +1 more source

Significance of long chain polyunsaturated fatty acids in human health

Clinical and Translational Medicine, Volume 6, Issue 1, December 2017., 2017
AbstractIn the last decades, the development of new technologies applied to lipidomics has revitalized the analysis of lipid profile alterations and the understanding of the underlying molecular mechanisms of lipid metabolism, together with their involvement in the occurrence of human disease.
Rafael Zárate, Nabil el Jaber‐Vazdekis, Noemi Tejera, José A. Pérez, Covadonga Rodríguez   +4 more
wiley   +1 more source

Azaphilic versus Carbophilic Coupling at CN Bonds: Key Steps in Titanium‐Assisted Multicomponent Reactions

Chemistry – A European Journal, Volume 21, Issue 51, Page 18730-18738, December 14, 2015., 2015
Key sequences: Consecutive C‐ and N‐arylation of N‐heterocyclic nitriles is mediated by titanium(IV) alkoxides. A powerful new multicomponent strategy for the rapid convergent assembly of structural complexity starting from simple N‐heterocyclic nitriles, Grignard reagents, and electrophilic coupling agents is described (see scheme).
Torsten Roth, Hubert Wadepohl, Eric Clot, Lutz H. Gade   +3 more
wiley   +1 more source

ProTranslator: zero-shot protein function prediction using textual description [PDF]

arXiv, 2022
Accurately finding proteins and genes that have a certain function is the prerequisite for a broad range of biomedical applications. Despite the encouraging progress of existing computational approaches in protein function prediction, it remains challenging to annotate proteins to a novel function that is not collected in the Gene Ontology and does not
arxiv  

Therapeutic intranasal vaccine HB-ATV-8 prevents atherogenesis and non-alcoholic fatty liver disease in a pig model of atherosclerosis [PDF]

, 2018
BACKGROUND AND AIMS: Atherosclerosis as an inflammatory disease involved in the etiology of cardiovascular disease worldwide, in our days demands an array of different therapeutic approaches in order to soon be able to visualize an effective prevention ...
Calixto-Tlacomulco, S., Damián-Zamacona, S., Delgado-Coello, B., Gutiérrez-Vidal, R., Mas-Oliva, J., Méndez-Acevedo, K.M.   +5 more
core   +1 more source

Effects of Tamarindus indica Fruit Pulp Extract on Abundance of HepG2 Cell Lysate Proteins and Their Possible Consequential Impact on Metabolism and Inflammation

BioMed Research International, Volume 2013, Issue 1, 2013., 2013
The fruit pulp extract of Tamarindus indica has been reported for its antioxidant and hypolipidemic properties. In this study, the methanol extract of T. indica fruit pulp was investigated for its effects on the abundance of HepG2 cell lysate proteins. Cell lysate was extracted from HepG2 cells grown in the absence and presence of the methanol extract ...
Ursula R. W. Chong, Puteri S. Abdul-Rahman, Azlina Abdul-Aziz, Onn H. Hashim, Sarni Mat-Junit, Antoni Camins   +5 more
wiley   +1 more source

BLOOD LIPID DISORDER IN MEN WITH INCREASED WAIST CIRCUMFERENCE COMPARED TO MEN HAVING NORMAL WAIST CIRCUMFERENCE WITHIN THE SAME CATEGORY OF BMI [PDF]

, 2015
Background: No local studies have been performed yet to investigate the influence of central or abdominal obesity on serum lipids in men having increased Waist Circumference (WC) compared to men with normal Waist Circumference values within the same BMI (
Abdallah, Rony, Atta-Alla, Ahmed E.S., Berry, Fadwa, Ezzedine, Mohamad, Faour, Tarek, Ghanem, Ricardos, Ghanem, Zizi M., Hassan, Khodor Haidar, Mortada, Mohamad, Nasser, Roudaina, Semaan, Pierre   +10 more
core   +4 more sources