Results 61 to 70 of about 266,324 (188)
Journal of Lipid Research, 1979 The interaction of sonicated, small vesicles of egg phosphatidylcholine and cholesterol (2:1, mol/mol) with bovine high density serum lipoproteins was examined in terms of lipid transfer between both types of particles and the resulting changes in ...
A Jonas
doaj
The intracellular control of cholesterol metabolism [PDF]
, 1988 The liver has a major role in the metabolism of cholesterol, being the main site of lipoprotein assembly and degradation and the only tissue where the metabolism of cholesterol to bile acids occurs.
Sampson, William James
core
Molecular Biology of the Cell, 2015 Biogenesis of the TGN-derived transport carriers CARTS requires the ER protein VAP and Golgi lipid transfer proteins, ceramide transfer protein and OSBP.
Yuichi Wakana +7 more
semanticscholar +1 more source
Quantitative Molecular Scaling Theory of Protein Amino Acid Sequences, Structure, and Functionality [PDF]
arXiv, 2016 Here we review the development of protein scaling theory, starting from backgrounds in mathematics and statistical mechanics, and leading to biomedical applications. Evolution has organized each protein family in different ways, but scaling theory is both simple and effective in providing readily transferable dynamical insights complementary for many ...
arxiv
PersGNN: Applying Topological Data Analysis and Geometric Deep Learning to Structure-Based Protein Function Prediction [PDF]
arXiv, 2020 Understanding protein structure-function relationships is a key challenge in computational biology, with applications across the biotechnology and pharmaceutical industries. While it is known that protein structure directly impacts protein function, many functional prediction tasks use only protein sequence.
arxiv
PoET: A generative model of protein families as sequences-of-sequences [PDF]
Advances in Neural Information Processing Systems (Vol. 36), 2023, 2023 Generative protein language models are a natural way to design new proteins with desired functions. However, current models are either difficult to direct to produce a protein from a specific family of interest, or must be trained on a large multiple sequence alignment (MSA) from the specific family of interest, making them unable to benefit from ...
arxiv
Entropy Transfer and Dynamics of Allostery in Proteins [PDF]
arXiv, 2017 Allostery is an intrinsic spatiotemporal property of all proteins, resulting from long range correlations in the order of several nanometers and time scales of nanoseconds. Information is carried asymmetrically from one part to another by entropy transfer.
arxiv
Vascular effects and safety of dalcetrapib in patients with or at risk of coronary heart disease: the dal-VESSEL randomized clinical trial [PDF]
, 2017 Aims High-density lipoprotein cholesterol (HDL-C) is inversely associated with cardiovascular (CV) events and thus an attractive therapeutic target. However, in spite of marked elevations in HDL-C, the first cholesterol transport protein (CETP) inhibitor
Deanfield, John E. +7 more
core
Oral Protein Therapy for the Future - Transport of Glycolipid-Modified Proteins: Vision or Fiction? [PDF]
, 2010 The reliable and early diagnosis of common complex multifactorial diseases depends on the individual determination of all (or as many as possible) polymorphisms of each susceptibility gene together with amount and type of the corresponding gene products ...
Mueller, Guenter
core +1 more source
Lipid transfer protein 3 as a target of MYB96 mediates freezing and drought stress in Arabidopsis
Journal of Experimental Botany, 2013 Several lipid-transfer proteins were reported to modulate the plant response to biotic stress; however, whether lipid-transfer proteins are also involved in abiotic stress remains unknown. This study characterized the function of a lipid-transfer protein,
Lin Guo +3 more
semanticscholar +1 more source