Nonvesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids
Nature, 2013 Phosphorylated sphingolipids ceramide-1-phosphate (C1P) and sphingosine-1-phosphate (S1P) have emerged as key regulators of cell growth, survival, migration and inflammation.
D. Simanshu +11 more
semanticscholar +1 more source
Intake of herring oil, but not of anchovy oil, resulted in a lower serum cholesterol concentration in male Zucker Diabetic Sprague Dawley rats [PDF]
Patients with type 2 diabetes have increased risks for dyslipidaemia and subsequently for developing vascular complications. A recent meta-analysis found that cetoleic acid (C22:1n-11) rich fish oils resulted in lower cholesterol concentration in rodents.
Gudbrandsen, Oddrun Anita +3 more
core +1 more source
Protein ScienceDue to the benefits of tomato as an antioxidant and vitamin source, allergy to this vegetable food is a clinically concerning problem. Sola l 7, a class I lipid transfer protein found in tomato seeds, has been identified as an allergen linked to severe ...
J. Parrón-Ballesteros +9 more
semanticscholar +1 more source
CoHSI IV: Unifying Horizontal and Vertical Gene Transfer - is Mechanism Irrelevant ? [PDF]
arXiv, 2018 In previous papers we have described with strong experimental support, the organising role that CoHSI (Conservation of Hartley-Shannon Information) plays in determining important global properties of all known proteins, from defining the length distribution, to the natural emergence of very long proteins and their relationship to evolutionary time ...
arxiv
Folding of Protein L with implications for collapse in the denatured state ensemble [PDF]
, 2016 A fundamental question in protein folding is whether the coil to globule collapse transition occurs during the initial stages of folding (burst-phase) or simultaneously with the protein folding transition. Single molecule fluorescence resonance energy transfer (FRET) and small angle X-ray scattering (SAXS) experiments disagree on whether Protein L ...
arxiv +1 more source
Effect of dietary elaidic versus vaccenic acid on blood and liver lipids in the hamster [PDF]
, 2001 Male hamsters (30 per group) were fed five different semi-purified diets ad libitum. The diets, containing 30% of energy (en%) as fat, differed in their dietary fat composition (specified fatty acids exchanged at 10 en%) and were fed for 4 weeks.
Berkel, Th.J.C. (Theo) van +3 more
core +2 more sources
Large-scale gene-centric analysis identifies novel variants for coronary artery disease [PDF]
, 2011 Coronary artery disease (CAD) has a significant genetic contribution that is incompletely characterized. To complement genome-wide association (GWA) studies, we conducted a large and systematic candidate gene study of CAD susceptibility, including ...
Strawbridge, Rona +1 more
core +1 more source
Cholesteryl ester transfer protein inhibition as a strategy to reduce cardiovascular risk
Journal of Lipid Research, 2012 Human and rabbit plasma contain a cholesteryl ester transfer protein (CETP) that promotes net mass transfers of cholesteryl esters from high density lipoproteins (HDL) to other plasma lipoprotein fractions. As predicted, inhibition of CETP in both humans
semanticscholar +1 more source
Scavenger receptor class B type I-mediated uptake of serum cholesterol is essential for optimal adrenal glucocorticoid production [PDF]
, 2009 Biopharmaceutic
Berkel, T.J.C. van +8 more
core +3 more sources