Results 41 to 50 of about 1,423 (95)

Multi‐Omics and ‐Organ Insights into Energy Metabolic Adaptations in Early Sepsis Onset

Advanced Science, Volume 12, Issue 30, August 14, 2025.
This study shows that patients at risk of sepsis have a distinct metabolite and lipid signature, including serine and aminoadipic acid, in their serum before clinical diagnosis. A mouse model of sepsis with a compatible serum signature reveals underlying metabolic changes, including mitochondrial adaptation, altered serine‐dependent purine metabolism ...
Lin‐Lin Xu, Zhengyuan Zhou, Sascha Schäuble, Wolfgang Vivas, Karen Dlubatz, Michael Bauer, Sebastian Weis, Mervyn Singer, Roman Lukaszewski, Gianni Panagiotou   +9 more
wiley   +1 more source

Enhancing quality and yield of recombinant secretory IgA antibodies in Nicotiana benthamiana by endoplasmic reticulum engineering

Plant Biotechnology Journal, Volume 23, Issue 4, Page 1178-1189, April 2025.
Summary The production of complex multimeric secretory immunoglobulins (SIgA) in Nicotiana benthamiana leaves is challenging, with significant reductions in complete protein assembly and consequently yield, being the most important difficulties. Expanding the physical dimensions of the ER to mimic professional antibody‐secreting cells can help to ...
Kathrin Göritzer, Stanislav Melnik, Jennifer Schwestka, Elsa Arcalis, Margit Drapal, Paul Fraser, Julian K‐C. Ma, Eva Stoger   +7 more
wiley   +1 more source

Detection, molecular function and mechanisms of m5C in cancer

Clinical and Translational Medicine, Volume 15, Issue 3, March 2025.
The role of m5C in cancers. The role of m5C regulators‐ writers, erasers, and readers‐ in various cancer types, including NSCLC, PCa, GC, AML, BCa, and HCC. Abstract Interest in RNA posttranscriptional modifications, particularly 5‐methylcytosine (m5C), has surged in recent years.
Linhui Zhang, Yuelong Li, Liqing Li, Fei Yao, Maoping Cai, Dingwei Ye, Yuanyuan Qu   +6 more
wiley   +1 more source

Dietary Nucleotides Improve Growth of Juvenile Eriocheir sinensis Under a Low‐Fish Meal Diet via Enhanced Feed Intake and Gut Health

Aquaculture Nutrition, Volume 2025, Issue 1, 2025.
Fish meal replacement in aquaculture feeds requires supplementing functional additives to maintain animal performance. Nucleotides are a promising supplement in finfish, but their role in crustaceans remains poorly understood, particularly under challenging low‐fish meal dietary conditions.
Song Wang, Wen Li, Yuxi Yan, Erchao Li, Xiaodan Wang, Jian G. Qin, Liqiao Chen, Mansour Torfi Mozanzadeh   +7 more
wiley   +1 more source

Magnolol Inhibits the Growth of Cryptococcus neoformans by Disrupting the GSH Oxidation–Reduction System

Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 2025, Issue 1, 2025.
Objective In this study, Cryptococcus neoformans BNCC225501 was used as research objects to explore the antifungal activity of magnolol. The molecular mechanisms underlying magnolol against Cryptococcus neoformans BNCC225501 were explored using metabolomics and transcriptomics.
Tiantian Wang, Pingchuan Li, Fenghua Zhang, Satabdi Datta Choudhury   +3 more
wiley   +1 more source

Ether‐Linked Glycerophospholipids Are Potential Chemo‐Desensitisers and Are Associated With Overall Survival in Carcinoma Patients

Journal of Cellular and Molecular Medicine, Volume 28, Issue 24, December 2024.
ABSTRACT Lipid reprogramming in carcinoma is reported to have a role in carcinogenesis, prognosis and therapy response. The lipid reprogramming could be contributed by either autonomous or nonautonomous resources. Since the nonautonomous lipid resources contributed by lipoproteins and their receptors have been reported in epithelial ovarian cancer (EOC)
Yu‐Ting Su, Wei‐Chun Chang, Lumin Chen, Ying‐Chun Yu, Wen‐Jen Lin, Jheng‐You Lin, Wei‐Chung Cheng, Juan‐Cheng Yang, Yao‐Ching Hung, Wen‐Lung Ma   +9 more
wiley   +1 more source

Phosphate cytidylyltransferase 1 choline-α (PCYT1A) [PDF]

, 2014

openalex   +1 more source

Glycerophospholipid Profiles of <i>Allomyrina dichotoma</i> Larvae at Different Instars Based on Lipidomics and Transcriptomics Suggest a Promising Lipid Source. [PDF]

Insects
Fang K, Liu JN, Wang CX, Wang T, Pan Y, Wang S, Xi JH.   +6 more
europepmc   +1 more source

Membrane curvature elastic stress triggers recruitment of PML-II onto the inner nuclear membrane. [PDF]

Mol Biol Cell
McPhee M, Salsman J, Newman AA, Voutsina N, Crosby AH, Dellaire G, Ridgway ND.   +6 more
europepmc   +1 more source

Genomic Insights into Lipid Dependency in Atypical Strains of Malassezia pachydermatis. [PDF]

Mycopathologia
Díaz L, Castellá G, Cigliano RA, Sanseverino W, Cabañes FJ.   +4 more
europepmc   +1 more source