Results 121 to 130 of about 273,862 (336)
Long Term High‐Salt Diet Induces Cognitive Impairments via Down‐Regulating SHANK1
Advanced Science, EarlyView.The study identifies a novel mechanistic link between long‐term HS diet and cognitive impairment, wherein PKA/CREB axis inactivation leads to SHANK1 reduction, synaptic damage, and cognitive deficits. Abstract High‐salt (HS) diet is an established risk factor for cognitive impairment, but the underlying mechanisms remain unclear.
Cuiping Guo +10 more
wiley +1 more source
Multi‐Omics and ‐Organ Insights into Energy Metabolic Adaptations in Early Sepsis Onset
Advanced Science, EarlyView.This study shows that patients at risk of sepsis have a distinct metabolite and lipid signature, including serine and aminoadipic acid, in their serum before clinical diagnosis. A mouse model of sepsis with a compatible serum signature reveals underlying metabolic changes, including mitochondrial adaptation, altered serine‐dependent purine metabolism ...
Lin‐Lin Xu +9 more
wiley +1 more source
Journal of Lipid Research, 1994 We have investigated the possible requirement of phosphatidylcholine for normal progression through the cell cycle of C3H/10T1/2 fibroblasts. Incubation of the cells in a medium with 0.5% serum synchronized the cells in the G0 stage of the cell cycle ...
F Tercé, H Brun, D E Vance
doaj
Modulation of DNA Methyltransferase 1 Profile by γ-lrradiation Followed by Methyl Donor Starvation
Pteridines, 2005 Role of one-carbon transfer agents methyl donors namely folate, choline and methionine in DNA methylation has been the subject of extensive investigation.
Batra Vipen +2 more
doaj +1 more source
Some New Physiologically Active Derivatives of Choline [PDF]
, 1914 Arthur James Ewins
openalex +1 more source
Genetic and Metabolic Controls for Sulfate Metabolism in \u3cem\u3eNeurospora crassa\u3c/em\u3e: Isolation and Study of Chromate-Resistant and Sulfate Transport-Negative Mutants [PDF]
, 1970 Mutants of Neurospora resistant to chromate were selected and all were found to map at a single genetic locus designated as cys-13. The chromate-resistant mutants grow at a wild-type rate on minimal media but are partially deficient in the transport of ...
Marzluf, George A.
core +1 more source
Advanced Science, EarlyView.The main process of the eutectic molten salt method and the direct regeneration of Spent lithium (Li)‐ion batteries by the eutectic molten salt method have brought structural, performance, environmental, and economic benefits. Abstract The rapid growth of electric vehicles (EVs) has significantly increased the demand for lithium (Li)‐ion batteries ...
Junyi Wang +3 more
wiley +1 more source
A glance at imaging bladder cancer. [PDF]
, 2018 Purpose: Early and accurate diagnosis of Bladder cancer (BCa) will contribute extensively to the management of the disease. The purpose of this review was to briefly describe the conventional imaging methods and other novel imaging modalities used for ...
Halpern, Ethan J. +4 more
core +1 more source
Advanced Science, EarlyView.Covalent organic framework (COF)‐reuterin induces trained immunity in tumor‐associated macrophages, promoting the generation of nitric oxide and reactive oxygen species, thereby enhancing the antitumor immune response. Additionally, COF‐Reuterin directly kills tumor cells while simultaneously eradicating pathogenic intratumoural bacteria.
Jian‐Gang Zhang +8 more
wiley +1 more source
Advanced Science, EarlyView.Iron‐induced lipid peroxidation of phosphatidylethanolamine (PE) species is the key driver of ferroptosis. The authors discovered that PHOSPHO1 lowers the level of PE in retinal pigment epithelial cells thus reducing the formation of lipid peroxides. Lowering PE levels can also prevent the creation of autolysosomes, reduce the production of free iron ...
Zhiyang Chen +19 more
wiley +1 more source