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The effects of inhibiting choline dehydrogenase on choline metabolism in mice
Biochemical Pharmacology, 19853,3-Dimethylbutanol (Dimbunol), a competitive inhibitor of choline dehydrogenase (CDH), and ethylcholine mustard aziridinium (ECMA), an effective irreversible inhibitor of both CDH and choline transport, were investigated for their effects upon the uptake and metabolism of [3H]choline in mice. Thirty minutes after Dimbunol administration (i.p.
Paul N. Barlow, Rm Marchbanks
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The Gravimetric Determination of Choline Chloride and Choline Citrate
Journal of the American Pharmaceutical Association (Scientific ed.), 1950A gravimetric method for choline chloride and choline citrate utilizing ammonium reineckate as an analytical reagent. The choline salts are precipitated as choline reineckate in aqueous solution, filtered off, dried, and weighed. The data collected indicate that the method has a standard deviation of less than 0.2 per cent and that it is reliable and ...
F.J. Bandelin, R.E. Pankratz
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Oral choline increases choline metabolites in human brain
Psychiatry Research: Neuroimaging, 2004Choline, a precursor of acetylcholine and phosphatidylcholine, is largely obtained from the diet. Animal studies demonstrate increased choline metabolites in brain following oral administration. Several proton magnetic resonance spectroscopy ((1)H-MRS) reports differ as to whether similar increases are observable in human subjects.
Nicholas Lange +5 more
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ACETYLCHOLINE AND CHOLINE ACETYLTRANSFERASE
Neurochemistry International, 1980The thermodynamics and kinetics of the alcoholysis of thiolesters are discussed and related to choline acetyltransferase. The conformation and rotational barriers of acetylcholine are described as is the specific inability of choline to induce depolarization. Evidence is presented for the involvement of imidazole and the non-involvement of thiol groups
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The solubilization of some steroids by phosphatidyl choline and lysophosphatidyl choline
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1967Abstract 1. 1. Quantitative estimations of the amounts of some steroids solubilized by ultrasonic dispersion with phosphatidyl choline in water, have indicated that mono-polar steroids are solubilized to a greater extent than multipolar steroids.
I.W. Kellaway, L. Saunders
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Glycerophosphoryl Choline as a Precursor of Free Choline in Mammalian Semen
Nature, 1953IN earlier studies it has been shown1,2 that the very considerable concentration of choline in human semen (200–300 mgm./100 gm.) arises through the enzymatic hydrolysis by the prostate phosphatase of phosphoryl choline formed in the vesicular glands.
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[247] Microdetermination of acetylcholinesterase, choline acetyltransferase, and choline
1971Publisher Summary This chapter discusses microdetermination of acetylcholinesterase, choline acetyltransferase, and choline. Labeled acetate produced by the enzymatic hydrolysis of acetylcholine is extracted into an organic solvent and counted.
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Reutilization of choline for synthesis of phosphatidyl choline and choline plasmalogen in rat brain
Journal of Neurochemistry, 1975P. Morrell +2 more
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