Results 91 to 100 of about 129,516 (303)

The nestin-expressing and non-expressing neurons in rat basal forebrain display different electrophysiological properties and project to hippocampus

BMC Neuroscience, 2011
Background Nestin-immunoreactive (nestin-ir) neurons have been identified in the medial septal/diagonal band complex (MS/DBB) of adult rat and human, but the significance of nestin expression in functional neurons is not clear.
Zhu Jianhua, Gu Huaiyu, Yao Zhibin, Zou Juntao, Guo Kaihua, Li Dongpei, Gao Tianming   +6 more
doaj   +1 more source

Integrative physiology of skeletal muscle for maintaining cognitive health

The Journal of Physiology, EarlyView.
Abstract figure legend Maintenance of brain/cognitive health and function is increasingly appreciated to be a systemic challenge. In particular, skeletal muscle influences the brain through release of myokines in response to contraction, which influence the expression of brain‐derived neurotrophic factor (BDNF) in the brain, a vital player in the ...
Matthew H. Brisendine, Joshua C. Drake
wiley   +1 more source

Prediabetic cardiomyopathy is attenuated by hypothalamic PVN oxytocin neuron activation

The Journal of Physiology, EarlyView.
Abstract figure legend A long‐term high‐fat, high‐fructose diet induces prediabetes with insulin resistance, hyperinsulinaemia, elevated triglycerides and metabolic‐associated steatotic liver disease (MASLD) in male rats. Animals developed prediabetic cardiomyopathy characterized by diastolic dysfunction, interstitial fibrosis and tachycardia ...
Anna Nilsson, Joan Escobar, Kira Kuraoka, Ian Venter, Cielo A. Carnate, Matthew W. Kay, David Mendelowitz, Kathryn J. Schunke   +7 more
wiley   +1 more source

Nobiletin, a Citrus Flavonoid That Improves Memory Impairment, Rescues Bulbectomy-Induced Cholinergic Neurodegeneration in Mice

Journal of Pharmacological Sciences, 2007
We have recently reported that nobiletin, a citrus flavonoid, improves impaired memory in olfactory-bulbectomized (OBX) mice, which have been widely utilized as a useful paradigm that shares some major clinical features of Alzheimer’s disease.
Akira Nakajima, Tohru Yamakuni, Mitsuya Haraguchi, Naoki Omae, Si-Young Song, Chieko Kato, Osamu Nakagawasai, Takeshi Tadano, Akihito Yokosuka, Yoshihiro Mimaki, Yutaka Sashida, Yasushi Ohizumi   +11 more
doaj   +1 more source

Amacrine cell inputs to OFF midget ganglion cells in macaque retina

The Journal of Physiology, EarlyView.
Abstract figure legend The goal of this study was to explain the findings from physiological studies that OFF midget ganglion cells had larger receptive field centers than expected from their dendritic field diameters. First, we confirmed that OFF mRGCs (OFF MGC) receive input from diffuse bipolar cells (DB) as well as OFF midget bipolar cells (FMB ...
David W. Marshak, Andrea S. Bordt, Emma R. Yang, Joel N. Yearick, Marcus Mazzaferri, James A. Kuchenbecker, Judith Mosinger Ogilvie, Sara S. Patterson, Jay Neitz   +8 more
wiley   +1 more source

Benefits of Maternal Choline Supplementation on Aged Basal Forebrain Cholinergic Neurons (BFCNs) in a Mouse Model of Down Syndrome and Alzheimer’s Disease

Biomolecules
Down syndrome (DS), stemming from the triplication of human chromosome 21, results in intellectual disability, with early mid-life onset of Alzheimer’s disease (AD) pathology.
Melissa J. Alldred, Harshitha Pidikiti, Kyrillos W. Ibrahim, Sang Han Lee, Adriana Heguy, Gabriela Chiosis, Elliott J. Mufson, Grace E. Stutzmann, Stephen D. Ginsberg   +8 more
doaj   +1 more source

Evaluation of the endogenous glucocorticoid hypothesis of denervation atrophy [PDF]

The effects are studied of the oral administration of RU38486, a potent selective glucocorticoid antagonist, on muscle weight, non-collagen protein content, and selected enzyme activities (choline acetyltransferase, glucose 6-phosphate dehydrogenase, and
Konagaya, Masaaki, Konagaya, Yoko, Max, Stephen R.   +2 more
core   +1 more source

Double labelling immunohistochemical characterization of autonomic sympathetic neurons innervating the sow retractor clitoridis muscle [PDF]

, 2008
Retrograde neuronal tracing and immunohistochemical methods were used to define the neurochemical content of sympathetic neurons projecting to the sow retractor clitoridis muscle (RCM). Differently from the other smooth muscles of genital organs, the RCM
Acone, Franca, Bo Minelli, Luisa, Botti, Maddalena, Gazza, Ferdinando, Palmieri, Giovanni, Panu, Rino, Ragionieri, Luisa   +6 more
core  

Adenosine receptor expression and function in rat striatal cholinergic interneurons [PDF]

, 2000
1. Cholinergic neurons were identified in rat striatal slices by their size, membrane properties, sensitivity to the NK(1) receptor agonist (Sar(9), Met(O(2))(11)) Substance P, and expression of choline acetyltransferase mRNA.
Alistair K Dixon, BELL, BRICE, BROWN, DIXON, DIXON, FINK, FREDHOLM, GRAYBIEL, GUBITZ, JIANG, JIN, JIN, KAWAGUCHI, KAWAGUCHI, Kevin Lee, KIRK, KIRKPATRICK, KUROKAWA, LEE, Leon Widdowson, MARCHBANKS, MORI, Peter J Richardson, PRESTON, REPPERT, RICHARDSON, RICHARDSON, RIVKEES, SCHIFFMANN, SCHIFFMANN, SVENNINGSSON, Tom C Freeman, Zoe Preston   +33 more
core   +2 more sources

The choline acetyltransferase of human placenta [PDF]

Biochemical Journal, 1966
1. Various methods for the extraction of choline acetyltransferase (acetyl-CoA-choline O-acetyltransferase, EC 2.3.1.6) from immature human placenta (18-28 weeks of gestation) are described. 2. The crude enzyme was found to be stable at -18 degrees and +4 degrees under a variety of conditions. 3.
openaire   +2 more sources