Ethanol transiently suppresses choline-acetyltransferase in basal nucleus of Meynert slices
Daniela Ehrlich+2 more
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Adult ciliary neurotrophic factor receptors help maintain facial motor neuron choline acetyltransferase expression in vivo following nerve crush. [PDF]
Lee N+4 more
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Distinct localization of peripheral and central types of choline acetyltransferase in the rat cochlea. [PDF]
Kitanishi T+7 more
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Regulation of mild moxibustion on non-neuronal cholinergic system in ulcerative colitis rats. [PDF]
Guangbin P+10 more
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Carnitine O-Acetyltransferase as a Central Player in Lipid and Branched-Chain Amino Acid Metabolism, Epigenetics, Cell Plasticity, and Organelle Function. [PDF]
Volpicella M+7 more
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Activation of Choline Acetyltransferase by Salts [PDF]
IONIZED salts affect choline acetyltransferase, EC 2.3.1.6 (ChA), in two important ways. They change the equilibrium between soluble and membrane-bound ChA, in preparations of ruptured nerve endings1,2. Further, the rate of synthesis of acetylcholine by soluble ChA and the Michaelis constants for this reaction depend on the concentration of salts3. The
A. K. Prince+3 more
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Acetylcholine is essential to neural function. It synthesis is catalyzed by choline acetyltransferase, the enzyme responsible for the acetylation of choline by acetyl coenzye A, a reaction favored slightly thermodymodynamically and not at all kinetically. An analytically pure enzyme still has not been obtained; however, method of purification have been
Henry G. Mautner, David Nachmansohn
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Choline acetyltransferase in schizophrenia
American Journal of Psychiatry, 1993To test the hypothesis that schizophrenia involves altered cholinergic tone in the pons, the authors studied post-mortem brain tissue from subjects with schizophrenia.The authors used Western immunoblot to measure the concentration of choline acetyltransferase, an acetylcholine synthesizing enzyme, in the post-mortem brain tissue of 25 schizophrenic ...
C. N. Karson+3 more
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The phosphorylation of choline acetyltransferase
Neurochemical Research, 1989Human placental Choline Acetyltransferase (ChAT) has been shown to be phosphorylated in vitro by kinases present in rat brain. Phosphorylation occurs at a single site with the exclusive phosphoamino acid being serine. ChAT phosphorylation was shown to be calcium, and not cyclic nucleotide, dependent and was inhibited by inhibitors of calcium/calmodulin
Louis B. Hersh, Gordon Bruce
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