Results 11 to 20 of about 129,516 (303)

Kinesin-II is required for axonal transport of choline acetyltransferase in Drosophila [PDF]

open access: yesJournal of Cell Biology, 1999
KLP64D and KLP68D are members of the kinesin-II family of proteins in Drosophila. Immunostaining for KLP68D and ribonucleic acid in situ hybridization for KLP64D demonstrated their preferential expression in cholinergic neurons.
Address Lawrence   +8 more
core   +5 more sources

A Novel Antiserum Against a Predicted Human Peripheral Choline Acetyltransferase (hpChAT) for Labeling Neuronal Structures in Human Colon [PDF]

open access: yesFrontiers in Neuroanatomy, 2019
Choline acetyltransferase (ChAT), the enzyme synthesizing acetylcholine (ACh), has an exon-skipping splice variant which is expressed preferentially in the peripheral nervous system (PNS) and thus termed peripheral ChAT (pChAT).
Jean-Pierre Bellier   +7 more
doaj   +2 more sources

Chaperone-Mediated Regulation of Choline Acetyltransferase Protein Stability and Activity by HSC/HSP70, HSP90, and p97/VCP [PDF]

open access: yesFrontiers in Molecular Neuroscience, 2017
Choline acetyltransferase (ChAT) synthesizes the neurotransmitter acetylcholine in cholinergic neurons, and mutations of this enzyme are linked to the neuromuscular disorder congenital myasthenic syndrome (CMS).
Trevor M. Morey   +7 more
doaj   +2 more sources

Correction: Perinatal Choline Supplementation Reduces Amyloidosis and Increases Choline Acetyltransferase Expression in the Hippocampus of the APPswePS1dE9 Alzheimer's Disease Model Mice. [PDF]

open access: yesPLoS ONE, 2017
[This corrects the article DOI: 10.1371/journal.pone.0170450.].
Tiffany J Mellott   +6 more
doaj   +2 more sources

Functional consequences and structural interpretation of mutations of human choline acetyltransferase

open access: greenHuman Mutation, 2011
Xin‐Ming Shen   +11 more
openalex   +3 more sources

Elusive physiological role of prostatic acid phosphatase (PAP): generation of choline for sperm motility via auto-and paracrine cholinergic signaling

open access: yesFrontiers in Physiology, 2023
Prostatic acid phosphatase (PAP) exists as two splice variants, secreted PAP and transmembrane PAP, the latter of which is implicated in antinociceptive signaling in dorsal root ganglia.
Peter J. Hanley
doaj   +1 more source

Rosiridin Attenuates Scopolamine-Induced Cognitive Impairments in Rats via Inhibition of Oxidative and Nitrative Stress Leaded Caspase-3/9 and TNF-α Signaling Pathways

open access: yesMolecules, 2022
Aim: A monoterpene and bioactive component of the plant Rhodiola rosea (R. rosea), rosiridin has beneficial effects on the human central nervous system and enhances brain function.
Muhammad Afzal   +7 more
doaj   +1 more source

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