Results 21 to 30 of about 129,516 (303)

Coexistence of choline acetyltransferase and GABA in axon terminals in the dorsal cap of the rat inferior olive [PDF]

, 1996
Caffé, A.R. (A.), Hawkins, R.K. (Richard), Zeeuw, C.I. (Chris) de   +2 more
core   +3 more sources

Circulating extracellular choline acetyltransferase regulates inflammation. [PDF]

J Intern Med, 2023
AbstractBackgroundCholine acetyltransferase (ChAT) is required for the biosynthesis of acetylcholine, the molecular mediator that inhibits cytokine production in the cholinergic anti‐inflammatory pathway of the vagus nerve inflammatory reflex. Abundant work has established the biology of cytoplasmic ChAT in neurons, but much less is known about the ...
Gabalski AH, Tynan A, Tsaava T, Li JH, Lee D, Hepler TD, Hide D, George S, Bravo Iñiguez CE, Thompson DA, Zhu C, Wang H, Brines M, Tracey KJ, Chavan SS.   +14 more
europepmc   +3 more sources

Effects of Radix Polygalae on Cognitive Decline and Depression in Estradiol Depletion Mouse Model of Menopause

Current Issues in Molecular Biology, 2021
Postmenopausal syndrome refers to symptoms caused by the gradual decrease in female hormones after mid-40 years. As a target organ of estrogen, decrease in estrogen causes various changes in brain function such as a decrease in choline acetyltransferase ...
Gaeul Han, Junhyuk Choi, Seung-Yun Cha, Byung Il Kim, Hee Kyung Kho, Maeng-Jin Jang, Mi Ae Kim, Sungho Maeng, Heeok Hong   +8 more
doaj   +1 more source

CXCL12 Regulates the Cholinergic Locus and CHT1 Through Akt Signaling Pathway

Cellular Physiology and Biochemistry, 2016
Background: CXCL12 is pivotal for cholinergic neurons, and it induces the expressions of several genes that are essential for synthesis and storage of acetylcholine(ACh), specifically choline acetyltransferase, vesicular ACh transporter (VAChT), and ...
Jing Yan, Wenhui Zhao, Meixia Guo, Xuefei Han, Zhiwei Feng   +4 more
doaj   +1 more source

The influence of non-neuronal cells on catecholamine and acetylcholine synthesis and accumulation in cultures of dissociated sympathetic neurons [PDF]

, 1974
The effects of several non-neuronal cell types on neurotransmitter synthesis in cultures of dissociated sympathetic neurons from the new-born rat were studied.
Chun, Linda L. Y., Patterson, Paul H.
core   +1 more source

Changes in neuromuscular structure and functions of human colon during ageing are region-dependent [PDF]

, 2018
Objective: To determine if human colonic neuromuscular functions decline with increasing age.Design: Looking for non-specific changes in neuromuscular function, a standard burst of electrical field stimulation (EFS) was used to evoke neuronally mediated (
Ahmed, Shafi, Broad, John, Carroll, Rebecca, Chin-Aleong, Joanne, Darreh-Shori, Taher, Elahi, Shezan, Karami, Azadeh, Knowles, Charles H., Kung, Victor W. S., Martin, Joanne E., Palmer, Alexandra, Saffrey, M. Jill, Sanger, Gareth John, Thaha, Mohamed Adhnan   +13 more
core   +2 more sources

Effects of Goldblatt hypertension on rats’ hippocampal cholinergic system

Translational Neuroscience, 2022
The classical renin-angiotensin system (RAS) has an important role in the cardiovascular system and water homeostasis in the body. Recently, the existence of RAS with all of its components has been shown in the mammalian brain.
Sepehri Hamid, Ganji Farzaneh, Nazari Zahra, Vahid Marzieh   +3 more
doaj   +1 more source

Dysregulated homeostasis of acetylcholine levels in immune cells of RR-multiple sclerosis patients [PDF]

, 2016
Multiple sclerosis (MS) is characterized by pro-inflammatory cytokine production. Acetylcholine (ACh) contributes to the modulation of central and peripheral inflammation.
Biagioni, Stefano, Costantini, Erica, DI BARI, Maria, Di Nicola, Marta, D’Angelo, Chiara, Galizia, Sabrina, Gasperini, Claudio, Orlando, Viviana, Porfilio, Italo, Reale, Marcella, Ruggieri, Serena, Tata, Ada Maria   +11 more
core   +2 more sources

Adolescent, but Not Adult, Binge Ethanol Exposure Leads to Persistent Global Reductions of Choline Acetyltransferase Expressing Neurons in Brain

PLoS ONE, 2014
During the adolescent transition from childhood to adulthood, notable maturational changes occur in brain neurotransmitter systems. The cholinergic system is composed of several distinct nuclei that exert neuromodulatory control over cognition, arousal ...
R. Vetreno, Margaret A. Broadwater, Wen Liu, L. Spear, F. Crews   +4 more
semanticscholar   +1 more source

Enhanced Cognitive Effects of Demethoxycurcumin, a Natural Derivative of Curcumin on Scopolamine-Induced Memory Impairment in Mice

Molecules, 2016
In the present study, we examined the ameliorating effects of demethoxycurcumin (DMC) on memory impairment induced by scopolamine using passive avoidance and Morris water maze tests in mice.
Dong Wook Lim, Hyun Jung Son, Min Young Um, In-Ho Kim, Daeseok Han, Suengmok Cho, Chang-Ho Lee   +6 more
doaj   +1 more source