Results 31 to 40 of about 129,516 (303)

Vascular Endothelial Growth Factor (VEGF) Prevents the Downregulation of the Cholinergic Phenotype in Axotomized Motoneurons of the Adult Rat [PDF]

, 2018
Vascular endothelial growth factor (VEGF) was initially characterized by its activity on the vascular system. However, there is growing evidence indicating that VEGF also acts as a neuroprotective factor, and that its administration to neurons suffering ...
Acosta, Lourdes, Morcuende Fernández, Sara R., Pastor Loro, Ángel Manuel, Rodríguez de la Cruz, Rosa María, Silva Hucha, Silvia   +4 more
core   +1 more source

Regulated Extracellular Choline Acetyltransferase Activity— The Plausible Missing Link of the Distant Action of Acetylcholine in the Cholinergic Anti-Inflammatory Pathway

PLoS ONE, 2013
Acetylcholine (ACh), the classical neurotransmitter, also affects a variety of nonexcitable cells, such as endothelia, microglia, astrocytes and lymphocytes in both the nervous system and secondary lymphoid organs.
Swetha Vijayaraghavan, A. Karami, S. Aeinehband, H. Behbahani, A. Grandien, B. Nilsson, K. Ekdahl, Rickard P. F. Lindblom, F. Piehl, T. Darreh-Shori   +9 more
semanticscholar   +1 more source

Basic and Clinical Aspects of Non-neuronal Acetylcholine: Overview of Non-neuronal Cholinergic Systems and Their Biological

Journal of Pharmacological Sciences, 2008
Acetylcholine (ACh) is a phylogenetically ancient molecule involved in cell-to-cell signaling in almost all life-forms on earth. Cholinergic components, including ACh, choline acetyltransferase, acetylcholinesterase, and muscarinic and nicotinic ACh ...
Significance Koichiro Kawashima, Takeshi Fujii   +1 more
doaj   +1 more source

Fluoxetine and Ketamine Reverse the Depressive but Not Anxiety Behavior Induced by Lesion of Cholinergic Neurons in the Horizontal Limb of the Diagonal Band of Broca in Male Rat

Frontiers in Behavioral Neuroscience, 2021
The basal forebrain cholinergic system is involved in cognitive processes, but the role of the basal forebrain cholinergic system in depression is unknown.
Linghong Chen, Linghong Chen, Yuting Ke, Yuting Ke, Yuting Ke, Hong Ma, Hong Ma, Lei Gao, Yiying Zhou, Huaqiang Zhu, Huifen Liu, Fuqiang Zhang, Wenhua Zhou, Wenhua Zhou   +13 more
doaj   +1 more source

Lipid-Mediated In Vivo Gene Transfer Replaces the Loss of Choline Acetyltransferase Activity after Unilateral Fimbria-Fornix Aspiration

Cell Transplantation, 2001
In Alzheimer's disease cholinergic neurons degenerate, resulting in loss of hippocampal acetylcholine. The fimbria-fornix aspiration is a well-known animal model mimicking hippocampal cholinergic deficiency.
Carla Weis, Walter A. Kaufmann, Christian Humpel   +2 more
doaj   +1 more source

Brain muscarinic cholinergic receptors in Huntington's disease [PDF]

, 1992
Muscarinic cholinergic receptors and choline acetyltransferase (ChAT) activity were studied in postmortem brain tissue from patients with Huntington's disease and matched control subjects.
Agid, Y., Javoy-Agid, F., Jenner, P., Lange, Klaus W., Marsden, C. D.   +4 more
core   +1 more source

Choline acetyltransferase mutations in myasthenic syndrome due to deficient acetylcholine resynthesis [PDF]

Muscle and Nerve, 2002
Ricardo A. Maselli, Darlene Chen, Delores Mo, Constance M. Bowe, Grace Fenton, Robert L. Wollmann   +5 more
openalex   +2 more sources

Design of primers and optimization of PCR conditions for the detection of alternatively spliced isoforms of mouse ChAT mRNA [PDF]

Journal of Biomedical & Clinical Research
Acetylcholine plays an important role as a neurotransmitter in the central and peripheral nervous systems. Its biosynthesis is catalyzed by choline acetyltransferase (ChAT).
Desislava Marinova, Stefan Trifonov
doaj   +3 more sources

Loss of Basal Forebrain Cholinergic Neurons Following Adolescent Binge Ethanol Exposure: Recovery With the Cholinesterase Inhibitor Galantamine

Frontiers in Behavioral Neuroscience, 2021
Binge drinking and alcohol abuse are common during adolescence and cause both cognitive deficits and lasting cholinergic pathology in the adult basal forebrain.
Fulton T. Crews, Fulton T. Crews, Rachael Fisher, Chloe Deason, Ryan P. Vetreno, Ryan P. Vetreno   +5 more
doaj   +1 more source

Molecular mechanisms of adaptation of the moderately halophilic bacterium Halobacillis halophilus to its environment [PDF]

, 2013
The capability of osmoadaptation is a prerequisite of organisms that live in an environment with changing salinities. Halobacillus halophilus is a moderately halophilic bacterium that grows between 0.4 and 3 M NaCl by accumulating both chloride and ...
Hänelt, Inga, Müller, Volker
core   +2 more sources