Results 61 to 70 of about 129,516 (303)

Differential roles of EA‐TRAPed cells in the anterior cingulate cortex across various intervention times in inflammatory pain

Animal Models and Experimental Medicine, EarlyView.
The cumulative effect of EA analgesia is partially attributed to the activation of EA‐TRAPed cells in ACC. Multiple EA sessions and single EA sessions activated different neuronal populations in the ACC. The enhanced analgesic effect of multiple EA sessions may be attributed to an increase in the proportion of GABAergic neurons within the ACC. Abstract
Zi Guo, Ru Ye, Lu Guan, Wei He, Shuang Qiu, Xiaomei Shao, Junfan Fang, Jianqiao Fang, Junying Du   +8 more
wiley   +1 more source

Chronic dietary ginseng extract administration ameliorates antioxidant and cholinergic systems in the brains of aged mice

Journal of Ginseng Research, 2017
Background: Black ginseng has a more potent biological activity than non-steamed ginseng. We investigated the effects of long-term intake of dietary black ginseng extract (BG) on antioxidant activity in aged mice.
Mi Ra Lee, Jin Yeul Ma, Chang Keun Sung
doaj   +1 more source

Characterization of the mechanism of prolonged adaptation to osmotic stress of Jeotgalibacillus malaysiensis via genome and transcriptome sequencing analyses [PDF]

, 2016
Jeotgalibacillus malaysiensis, a moderate halophilic bacterium isolated from a pelagic area, can endure higher concentrations of sodium chloride (NaCl) than other Jeotgalibacillus type strains.
Chan, K. G., Ee, R., Goh, K. M., Lee, S. K., Lim, Y. L., Manan, F. A., Yaakop, A. S.   +6 more
core   +2 more sources

TARDBP (TDP‐43) Knock‐in Zebrafish Display a Late‐Onset Motor Phenotype and Loss of Large Spinal Cord Motor Neurons

Annals of Neurology, EarlyView.
Objective Mutations in TARDBP (encoding TDP‐43) are associated with the neurodegenerative disease amyotrophic lateral sclerosis (ALS) and include familial missense mutations where there are a lack of models and mechanisms examining how they are pathogenic.
Ziyaan A. Harji, Christian J. Rampal, Esteban C. Rodríguez, Virginie Petel Légaré, Alexandra Lissouba, Sabrina Semmler, Meijiang Liao, Jay P. Ross, Guy A. Rouleau, Christine Vande Velde, Gary A.B. Armstrong   +10 more
wiley   +1 more source

Cognitive impairment induced by sevoflurane anesthesia is mediated by the cholinergic system after gastrointestinal surgery in older patients: A randomized, controlled trial

Ibrain
Delayed neurocognitive recovery after surgery is associated with increased morbidity and mortality. However, its mechanism of action remains controversial and complex.
Xing‐Xing Liu, Qing‐Xu Yang, Yi Guo, Miao He, Zhen‐He Yu, Qi Tian, Zhao‐Qiong Zhu   +6 more
doaj   +1 more source

A Case of Congenital Myasthenia Gravis due to ChAT Gene Mutation in a Term Neonate: A Case Report

American Journal of Perinatology Reports
Congenital myasthenia gravis syndrome (CMS) is a rare genetic heterogeneous disorder due to abnormal neuromuscular transmission caused by several genes.
Maya Soufan, Haya Soufan, Kushagra Chaudhari, Judith Klarr   +3 more
doaj   +1 more source

Nuclear 82-kDa choline acetyltransferase decreases amyloidogenic APP metabolism in neurons from APP/PS1 transgenic mice

Neurobiology of Disease, 2014
Alzheimer disease (AD) is associated with increased amyloidogenic processing of amyloid precursor protein (APP) to β-amyloid peptides (Aβ), cholinergic neuron loss with decreased choline acetyltransferase (ChAT) activity, and cognitive dysfunction.
Shawn Albers, Fatima Inthathirath, Sandeep K. Gill, Warren Winick-Ng, Ewa Jaworski, Daisy Y.L. Wong, Robert Gros, R. Jane Rylett   +7 more
doaj   +1 more source

Dendritic and axonal targeting patterns of a genetically-specified class of retinal ganglion cells that participate in image-forming circuits. [PDF]

, 2014
BackgroundThere are numerous functional types of retinal ganglion cells (RGCs), each participating in circuits that encode a specific aspect of the visual scene.
Feldheim, David A, Feller, Marla B, Gonzalez, Cristina, Huberman, Andrew D, Sweeney, Neal T, Triplett, Jason W, Wei, Wei   +6 more
core   +2 more sources

Enteric Nervous System Remodeling in a Rat Model of Spinal Cord Injury: A Pilot Study

Neurotrauma Reports, 2020
The physiopathology of digestive disorders in patients with spinal cord injury (SCI) remains largely unknown, particularly the involvement of the enteric nervous system (ENS). We aimed in a rat model of chronic thoracic SCI to characterize (1) changes in
Chlo? Lef?vre, Anne Bessard, Philippe Aubert, Charles Joussain, Fran?ois Giuliano, Delphine Behr-Roussel, Marie-Aim?e Perrouin-Verbe, Brigitte Perrouin-Verbe, Charl?ne Brochard, Michel Neunlist   +9 more
doaj   +1 more source

Neurochemical characterization of extrinsic nerves in myenteric ganglia of the guinea pig distal colon [PDF]

, 2014
"This is the peer reviewed version of the following article: [Chen, B. N., Sharrad, D. F., Hibberd, T. J., Zagorodnyuk, V. P., Costa, M. and Brookes, S. J.H.
Brookes, Simon Jonathan, Chen, Bao Nan, Costa, Marcello, Hibberd, TJ, Sharrad, DF, Zagorodnyuk, Vladimir Petrovich   +5 more
core   +1 more source