Tissue fixation is critical for immunohistochemistry. Recently, we developed a zinc-ethanol-formalin fixative (ZEF), and the present study was aimed to assess the applicability of the ZEF for the human brain histology and immunohistochemistry and to ...
D.E. Korzhevskii+3 more
doaj +1 more source
Repeated Intravenous Administration of Human Neural Stem Cells Producing Choline Acetyltransferase Exerts Anti-Aging Effects in Male F344 Rats. [PDF]
Kyung J+7 more
europepmc +1 more source
Engineering Assembloids to Mimic Graft‐Host Skeletal Muscle Interaction
This study develops a graft‐host skeletal muscle assembloid model combining neuromuscular organoids with tissue‐engineered constructs. Pre‐seeding decellularized muscles with myogenic cells enhances cell migration and axon invasion from the organoid. The model exhibits regenerative capacity following acute damage, advancing the understanding of human ...
Lucia Rossi+13 more
wiley +1 more source
Disturbances in Ca2+ homeostasis and mitochondrial dysfunction have emerged as major pathogenic features in familial and sporadic forms of Amyotrophic Lateral Sclerosis (ALS), a fatal degenerative motor neuron disease. However, the distinct molecular ALS-
Tobias eMühling+4 more
doaj +1 more source
A novel transgenic mouse model expressing primate-specific nuclear choline acetyltransferase: insights into potential cholinergic vulnerability. [PDF]
AlQot HE, Rylett RJ.
europepmc +1 more source
Choline Acetyltransferase from Rat Brain
Abstract The localization, purification, and some enzymatic properties of choline acetyltransferase from rat brain were studied. Most assays were performed with a specific radiometric micromethod. Solubilization of the enzyme was examined after homogenization of cerebral cortices by means which disintegrate nerve endings. In isotonic KCl the enzyme was
Jeffrey K. Saelens+2 more
openaire +3 more sources
The N1 peptide specifically targets neurons, enabling cytosolic delivery of fluorescent dyes and proteins for super‐resolution imaging and functional genetic modification. Abstract Efficient delivery of biomolecules into neurons has significant impacts on therapeutic applications in the central nervous system (CNS) and fundamental neuroscience research.
Xiaoqian Ge+16 more
wiley +1 more source
Isotopic exchange between acetylcholine and [Me-14C] choline catalysed by human placental choline acetyltransferase [PDF]
David Morris, Darshan S. Grewaal
openalex +1 more source
The Brain of the African Wild Dog. V. The Somatosensory System and Vestibular Nuclear Complex
Lateral view of the African wild dog brain showing the location of the somatosensory cortical areas in relation to the parietal multisensory region (PP), occipital visual cortical areas (17, 18, 19, 21, SS, T), and temporal auditory cortical areas (AAF, AI AII).
Samson Chengetanai+6 more
wiley +1 more source
Improvement of Cognitive Function in Ovariectomized Rats by Human Neural Stem Cells Overexpressing Choline Acetyltransferase via Secretion of NGF and BDNF. [PDF]
Yoon EJ, Choi Y, Park D.
europepmc +1 more source