Results 71 to 80 of about 129,516 (303)

Stem cell therapy for Alzheimer's disease: hype or hope? [PDF]

open access: yes, 2013
Alzheimers disease (AD) is the most common neurodegenerative disease affecting millions of people in the world. Cognitive impairments such as progressive memory loss are devastating manifestations from this disease.
Liu, AKL
core   +1 more source

Ketogenic diet for infantile epileptic spasms

open access: yesEpilepsia Open, EarlyView.
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury   +3 more
wiley   +1 more source

Sex Differences in Context-Driven Reinstatement of Methamphetamine Seeking is Associated with Distinct Neuroadaptations in the Dentate Gyrus

open access: yesBrain Sciences, 2018
The present study examined differences in operant responses in adult male and female rats during distinct phases of addiction. Males and females demonstrated escalation in methamphetamine (0.05 mg/kg, i.v.) intake with females showing enhanced latency to
Yoshio Takashima   +8 more
doaj   +1 more source

Nutritional Value and Memory‐Improving Effects of Seven Major Nuts: A Comprehensive Study Using Network Pharmacology and In Vivo Assays

open access: yesFood Frontiers, EarlyView.
This study highlights the memory‐enhancing effects of walnuts, almonds, and Torreya, with walnuts showing the strongest potential to improve cognitive function and delay brain aging. ABSTRACT This study explored the memory‐enhancing potential of seven commercially available nuts through nutritional profiling, metabolomics, network pharmacology, and ...
Jiamin Chen   +10 more
wiley   +1 more source

Establishing Human Male and Female Models of Cholinergic Neurons via Neurokine-Mediated Differentiation of LA-N-2 and LA-N-5 Neuroblastoma Cells

open access: yesSTAR Protocols, 2020
Summary: Cholinergic neurons control numerous primate-specific and sexually dimorphic brain functions. Here, we present our differentiation protocol for the closely related human female and male neuroblastoma-originated cell lines LA-N-2 and LA-N-5.
Sebastian Lobentanzer   +2 more
doaj   +1 more source

Neuronal Premotor Networks Involved in Eyelid Responses: Retrograde Transneuronal Tracing with Rabies Virus from the Orbicularis Oculi Muscle in the Rat [PDF]

open access: yes, 2002
Retrograde transneuronal tracing with rabies virus from the right orbicularis oculi muscle was used to identify neural networks underlying spontaneous, reflex, and learned blinks.
Delgado García, José María   +2 more
core   +2 more sources

Anterior Nasal Nerves: A Cadaveric Anatomic and Immunohistochemical Analysis

open access: yesThe Laryngoscope, EarlyView.
Anterior nasal nerves (ANNs) were identified in all cadavers, with more supplying the anterolateral nasal wall (ALNW) than the anterior portion of the inferior turbinate (IT), between the pyriform aperture (PA) and middle turbinate (MT). Both sensory and autonomic nerve markers were also identified in the ANNs.
John R. Craig   +6 more
wiley   +1 more source

Cell type-specific regulation of choline acetyltransferase gene expression - Role of the neuron-restrictive silencer element and cholinergic-specific enhancer [PDF]

open access: yes, 1996
This study demonstrates the presence of positive and negative regulatory elements within a 2336-base pair-long region of the rat choline acetyltransferase (ChAT) gene promoter that cooperate to direct cell type-specific expression in cholinergic cells. A
Anderson, David J.   +3 more
core  

Electrocochleographic Changes Predict an Early Sign of Cochlear Degeneration

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objectives The purpose of this study is to identify the earliest appearing auditory electrophysiological indicators that change with age progression in young adults with normal hearing, and to analyze the frequency distribution patterns of these markers in the cochlear.
Min‐Fei Qian   +6 more
wiley   +1 more source

Axons Giving Rise to the Palisade Endings of Feline Extraocular Muscles Display Motor Features [PDF]

open access: yes, 2013
Palisade endings are nerve specializations found in the extraocular muscles (EOMs) of mammals, including primates. They have long been postulated to be proprioceptors. It was recently demonstrated that palisade endings are cholinergic and that in monkeys
Davis López de Carrizosa, María América   +5 more
core   +1 more source

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