Results 101 to 110 of about 500,160 (249)

INFLUENCE OF DIETARY CHOLINE AND PROTEIN ON THE LEVEL OF PHOSPHOLIPID IN THE SERUM OF THE RAT

, 1957
Albino rats weighing 180–200 g. were fed diets containing 5, 9, and 19% protein. The influence of these diets, both with and without additional choline, on the level of serum phospholipid was measured and it was found that only in the presence of dietary
Jessie M. Lang, Bruno Rosenfeld
core   +1 more source

Advanced In Vitro Platforms for Experimental Liver Research: From Organoids and Liver‐on‐Chip to Omics and Artificial Intelligence

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Hepatocytes perform essential physiological functions in the human body. Gaining more profound insight into the liver structure, diseases, and physiology by using in vitro models can help to propose more relevant clinical applications. Conventional in vitro liver models, such as two‐dimensional (2D) cell cultures, fail to adequately replicate ...
Seyedeh Kiana Teymorian, Pedram Asadi Sarabi, Abbas Piryaei, Massoud Vosough   +3 more
wiley   +1 more source

Folic Acid Supplementation Attenuates Hepatic Steatosis by Enhancing Choline Availability and Remodeling Fatty Acid Profiles in Mice Fed a High‐Fat Diet

FASEB BioAdvances
High‐fat diets (HFDs) are a well‐established cause of hepatic steatosis, a condition associated with altered hepatic fatty acid metabolism and reduced choline availability.
Eva Kranenburg, Ruslan Kubant, Zeyu Yang, Adam H. Metherel, Chuck T. Chen, Jacqueline L. Beaudry, Clara E. Cho, Perlina Vaz, G. Harvey Anderson   +8 more
doaj   +1 more source

Regulation by dietary choline of hepatic fatty acid synthetase in the rat

Journal of Lipid Research, 1973
Fatty acid synthetase activity was measured in the high-speed supernatant fraction of liver homogenates from rats fed a semisynthetic diet low in lipotropic factors.
Bruno Rosenfeld
doaj   +1 more source

Induction Temperature and Feeding Profile Shape the Partitioning Between Soluble Product and Inclusion Body Formation in Escherichia coli

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Inclusion body (IB) processes yielding the recombinant product only as IBs are long‐established in the biopharmaceutical industry. Yet, for recombinant proteins that accumulate both IBs and soluble fraction depending on the selected upstream processing (USP) strategy, the influence of process parameters on the partitioning between both forms ...
Mohamed Elshazly, Lisa Ying, Florian Gisperg, Robert Klausser, Eva Prada Brichtova, Noah Schütz, Oliver Spadiut, Julian Kopp   +7 more
wiley   +1 more source

TNAP dephosphorylates phosphocholine and phosphoethanolamine and participates in triglyceride transport from the liver to the bloodstream

Communications Biology
Tissue-nonspecific alkaline phosphatase (TNAP) is primarily known for its role in skeletal mineralization, through the hydrolysis of inorganic pyrophosphate (PPi).
Eva Drevet Mulard, Iliass Imam, Pierre-Damien Coureux, Anne Briolay, Laurence Bessueille, Antoine Tarby, Stéphane Balayssac, Sonoko Narisawa, Felix Lecornu, Véronique Gilard, Sébastien Violot, Jose Luis Millan, Gilles Jean Philippe Rautureau, Lionel Ballut, David Magne   +14 more
doaj   +1 more source

Choline in Adolescent Pregnancy: The Impact on Fetal Brain Development and Long-Term Cognitive Outcomes of Offspring

Medicina
Pregnancy in adolescence represents a major nutritional challenge, with competing demands between maternal development and fetal growth. Choline is the essential nutrient with a critical role for fetal brain development and exhibits distinct metabolic ...
Abdul Jabar Khudor, Marius Alexandru Moga, Oana Gabriela Dimienescu, Andrada Camelia Nicolau, Cristian Andrei Arvătescu, Mircea Daniel Hogea, Natalia Ciobanu   +6 more
doaj   +1 more source

Suppression Effects of Betaine-Enriched Spinach on Hyperhomocysteinemia Induced by Guanidinoacetic Acid and Choline Deficiency in Rats

The Scientific World Journal, 2014
Betaine is an important natural component of rich food sources, especially spinach. Rats were fed diets with betaine or spinach powder at the same level of betaine for 10 days to investigate the dose-dependent effects of spinach powder supplementation on
Yi-Qun Liu, Zheng Jia, Feng Han, Takahiro Inakuma, Tatsuya Miyashita, Kimio Sugiyama, Li-Cui Sun, Xue-Song Xiang, Zhen-Wu Huang   +8 more
doaj   +1 more source

Mitochondria‐endoplasmic reticulum organelle glue as maturation promoter for origination/dimensional dual‐cross cardiomyocytes

BMEMat, EarlyView.
Mitochondria‐endoplasmic reticulum contact sites (MERCS) are areas where the mitochondria and endoplasmic reticulum closely interact. In this study, we utilize synthetic organelle glues to artificially engineer MERCS for regulating cardiomyocyte development, through which the immature and chemo‐plasticity issues of undifferentiated cells are addressed.
Wei Tang, Hao Sun, Chenqi Duan, Jiajia Chang, Yuxing Wang, Ming Zhao, Huiyue Zhao, Shan Lu, Yang Yang, Da Huo   +9 more
wiley   +1 more source

Donor‐To‐Recipient Mean Axonal Count Ratios of Upper Limb Nerves Used in Nerve Transfer Surgery: A Systematic Review of Histomorphometric Cadaveric Studies

Clinical Anatomy, EarlyView.
ABSTRACT Nerve transfer surgery may be performed to restore sensorimotor function following peripheral nerve trauma or dysfunction. There is biological plausibility and limited correlative evidence that donor‐to‐recipient axon count ratios may impact functional outcomes.
Samuel James Ng, Rosa Morgan‐Young, Alexander Laing, Rebecca Molden, Suzanne Thomson   +4 more
wiley   +1 more source