Results 201 to 210 of about 500,160 (249)
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Choline Deficiency and Chemical Carcinogenesis
1986We have reviewed the current status of our knowledge concerning the biologic effects of dietary choline (lipotrope) deficiency in modifying chemical carcinogenesis in experimental animals and discussed its possible mechanisms. Choline deficiency produces various pathologic lesions, involving virtually every organ of the body, as a result of a decrease ...
H, Shinozuka, S L, Katyal, M I, Perera
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Disturbances in Oxidative Metabolism in Choline Deficiency
Nature, 1946THE common symptoms in rats on a choline-deficient diet are, as is well known, fatty liver, impeded growth, and in young animals renal haemorrhages (for references see Best1). There has been discussion as to whether the vitamin character of choline is due only to its content of labile methyl groups, or if the lipotropic action has a more specific ...
N O, ABDON, N E, BORGLIN
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Choline metabolism in normal and choline-deficient rats of different ages
Archives of Biochemistry and Biophysics, 1965Abstract The rates of synthesis and degradation (decay times) of lipid-bound, liver choline were studied in normal and choline-deficient rats with body weights in the 40–100 gm range. The rate of choline synthesis from l -methionine-CH 3 -C 14 decreased exponentially as the body weight increased and was greater in the choline-deficient rat than in ...
I C, Wells, C N, Remy
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Carnitine depletion in the choline-deficient state
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1967Abstract 1. 1. Dietary choline deficiency causes a decrease in the heart and liver levels of carnitine and in the rate of long-chain fatty acid oxidation by myocardial and hepatic homogenates. 2. 2. Addition of carnitine in vitro, but not of choline, to tissue homogenates increases the rate of long-chain fatty acid oxidation, and decreases ...
C, Corredor, C, Mansbach, R, Bressler
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Role of lipoperoxidation in early choline deficiency
Experimental and Molecular Pathology, 1970Abstract Although a significant increase in hepatic triglycerides and an alteration in the relative lecithin contents of hepatic mitochondria were found in rats 12 hours after the institution of a cholinedeficient regimen, neither in their mitochondria nor in their microsomal fractions could diene conjugation be detected at 3, 6, 12, or 120 hours. It
A K, Ghoshal +3 more
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Ethanol Feeding and Choline Deficiency as Influences on Hepatic Choline Uptake
The Journal of Nutrition, 1971This study shows that rats fed a choline-deficient diet for 5 days have livers which under perfusion have an increased ability to take up exogenous cholinc. Choline-deficient animals fed the diet for 21 days have livers that show normal choline uptake.
A J, Barak, D J, Tuma, H C, Beckenhauer
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Metabolism, 1971
Abstract In the present investigation we have examined the body pool, turnover time, half-life, and tissue levels of carnitine as well as the metabolism of radioactive carnitine in choline-deficient, alloxan-diabetic choline deficient and alloxan-diabetic choline deficient insulin-treated rats. The carnitine body pool in normal rats was 25.6; choline-
M A, Mehlman +2 more
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Abstract In the present investigation we have examined the body pool, turnover time, half-life, and tissue levels of carnitine as well as the metabolism of radioactive carnitine in choline-deficient, alloxan-diabetic choline deficient and alloxan-diabetic choline deficient insulin-treated rats. The carnitine body pool in normal rats was 25.6; choline-
M A, Mehlman +2 more
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Choline in Plasma in Children, with a study of induced choline deficiency
Acta Paediatrica, 1948SUMMARYThe total choline content (= mainly lipid bound choline) in plasma in children is the same as in adults, or 18–32 mg%. In new born babies it is only 7–14 mg%, whereas in acute nephritis in children there is often an elevation of all lipid components of plasma including the choline containing.An attempt to provoke choline deficiency in an infant ...
GUNNAR BRANTE, LARS SÖDERHJELM
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Phospholipids and Choline Deficiency
1990Lecithin (phosphatidylcholine; PtdCho) is the major phospholipid constituent of most membranes, and it is vital to the normal function of every cell and organ. PtdCho is synthesized from choline in all organs29,30. Much of this choline comes from the diet.
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Choline deficiency in the mouse
American Journal of Anatomy, 1957R D, MEADER, W L, WILLIAMS
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