Results 241 to 250 of about 59,547 (299)
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Lipid Peroxidation in Choline-Methionine Deficiency
Free Radical Research Communications, 1987A deficiency of choline and methionine is hepatocarcinogenic and is associated with an apparent increase in lipid peroxidation. In this study the susceptibility of microsomes and nuclei to ferritin-dependent lipid peroxidation is examined together with the status of the peroxidation-protective systems.
K H, Tan, D J, Meyer, B, Ketterer
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Choline Deficiency in the Guinea Pig
Nature, 1954THE brief report by Reid1 of the “production of clear-cut deficiencies of … choline …” in the guinea pig is of considerable interest, as Handler2 had previously failed to produce fatty livers in guinea pigs maintained on a hypolipotropic diet and had correlated this failure with the low choline oxidase content of guinea pig liver8.
W G, CASSELMAN, G R, WILLIAMS
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CHOLINE DEFICIENCY IN THE GUINEA PIG
Canadian Journal of Biochemistry and Physiology, 1957Young guinea pigs (4–6 days of age) fed a choline-deficient diet grew slowly and died within 3 to 4 weeks, at which time the livers showed only traces of stainable fat. Animals fed the diet supplemented with choline grew at the rate of 5.5 to 6.0 g. per day.
C C, LUCAS, R J, YOUNG
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Metabolism, 1971
Abstract In the present investigation we have examined the body pool, turnover time, half-life, and tissue levels of carnitine as well as the metabolism of radioactive carnitine in choline-deficient, alloxan-diabetic choline deficient and alloxan-diabetic choline deficient insulin-treated rats. The carnitine body pool in normal rats was 25.6; choline-
M A, Mehlman +2 more
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Abstract In the present investigation we have examined the body pool, turnover time, half-life, and tissue levels of carnitine as well as the metabolism of radioactive carnitine in choline-deficient, alloxan-diabetic choline deficient and alloxan-diabetic choline deficient insulin-treated rats. The carnitine body pool in normal rats was 25.6; choline-
M A, Mehlman +2 more
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The Relationship of Choline and Carnitine in the Choline Deficient Rat
The Journal of Nutrition, 1978Levels of carnitine in choline deficient and choline supplemented rats were measured in heart, skeletal muscle, plasma, and liver after various treatments. A decreased hepatic concentration of carnitine was shown to be closely correlated to the deficiency in dietary choline.
A L, Carter, R, Frenkel
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Choline metabolism in normal and choline-deficient rats of different ages
Archives of Biochemistry and Biophysics, 1965Abstract The rates of synthesis and degradation (decay times) of lipid-bound, liver choline were studied in normal and choline-deficient rats with body weights in the 40–100 gm range. The rate of choline synthesis from l -methionine-CH 3 -C 14 decreased exponentially as the body weight increased and was greater in the choline-deficient rat than in ...
I C, Wells, C N, Remy
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INTRAOCULAR HEMORRHAGES IN CHOLINE DEFICIENCY
Archives of Ophthalmology, 1943Recently it has been demonstrated that serious changes can be produced within two weeks when weanling rats are placed on choline-poor diets. 1 Hemorrhagic kidneys and adrenals, fatty liver, enlarged spleen and atrophied thymus are the most consistent findings. In addition, hemorrhages are frequently found in the lungs, myocardium, lymph nodes and eyes.
J. G. BELLOWS, H. CHINN
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Ethanol Feeding and Choline Deficiency as Influences on Hepatic Choline Uptake
The Journal of Nutrition, 1971This study shows that rats fed a choline-deficient diet for 5 days have livers which under perfusion have an increased ability to take up exogenous cholinc. Choline-deficient animals fed the diet for 21 days have livers that show normal choline uptake.
A J, Barak, D J, Tuma, H C, Beckenhauer
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Hypertension produced by choline deficiency in rats
Pathology, 1970Summary Choline deficiency has been produced in young rats and some factors which affect the resulting hypertension have been studied. A micro-sphygmomanometric apparatus was devised to measure blood pressures which were found to rise after 7–10 days on the choline deficient diet to values 25–35 mm. Hg. higher than those of supplemented rats.
Kratzing, C. C. +2 more
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Phospholipids and Choline Deficiency
1990Lecithin (phosphatidylcholine; PtdCho) is the major phospholipid constituent of most membranes, and it is vital to the normal function of every cell and organ. PtdCho is synthesized from choline in all organs29,30. Much of this choline comes from the diet.
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