Results 101 to 110 of about 7,719 (129)

Developmental Differences Between Soluble and Membrane‐Bound Fractions of Choline‐O‐Acetyltransferase in Neonatal Mouse Brain

Journal of Neurochemistry, 1984
Abstract: Three fractions (one soluble and two membrane‐bound) of choline acetyltransferase (ChAT) isolated from a nerve ending fraction of mouse forebrain, which have previously been reported to differ in several biochemical and physical aspects, were also found to differ in their rates of postnatal development.
C G, Benishin, P T, Carroll
openaire   +2 more sources

Biochemical and morphometric studies of the relationship of acetylcholine synthesis and vesicle numbers after stimulation of frog neuromuscular junctions: The effect of acholine-O-acetyltransferase inhibitor

Brain Research, 1978
The present study compares choline acetylase (ChAc) activity with morphometric determinations of synaptic vesicles at the neuromuscular junctions of frog pectoralis muscle subjected to high and low frequency stimulation in the presence or absence of NVP, a ChAc inhibitor.
F M, Benes, R J, Barrnett
openaire   +2 more sources

Effect of Phospholipase C from Bacillus cereus on the Release of Membrane‐Bound Choline‐O‐Acetyltransferase from Rat Hippocampal Tissue

Journal of Neurochemistry, 1990
Abstract: Some of the enzyme choline‐O‐acetyltransferase (ChAT) associated with central cholinergic nerve terminals appears to be nonionically associated with membranes. In the present study, we tested the possibility that some membrane‐bound ChAT might be anchored to membranes by a phosphatidylinositol linkage by incubating rat hippocampal tissue ...
P T, Carroll, L K, Smith
openaire   +2 more sources

Veratridine-induced activation ofcholine-O-acetyltransferase activity in rat hippocampal tissue: relationship to the veratridine-induced release of acetylcholine

Brain Research, 1987
The effect of veratridine depolarization on the activity of 3 choline-O-acetyltransferase (ChAT) fractions in rat hippocampal tissue was investigated. Those concentrations of veratridine which augmented acetylcholine (ACh) release also increased the activity of water and detergent soluble ChAT fractions.
openaire   +2 more sources

Differential sensitivity of soluble and membrane-bound forms of choline O-acetyltransferase to inhibition by Coenzyme A

Biochemical Pharmacology, 1981
C G, Benishin, P T, Carroll
openaire   +2 more sources

Choline O-acetyltransferase

1996
Dietmar Schomburg, Dörte Stephan
openaire   +1 more source

Mutations in choline-O-acetyltransferase are associated with treatable cognitive decline, dysautonomia, and adverse medication responses — Time to CHAT with your patients?

Mitochondrion, 2013
Stacey Wong, Katherine Sheldon, Richard Boles   +2 more
openaire   +1 more source

In Situ Assembly of Choline Acetyltransferase Ligands by a Hydrothiolation Reaction Reveals Key Determinants for Inhibitor Design

Angewandte Chemie - International Edition, 2021
Christian Lejon, Christine Akfur, Mattias Hedenström   +2 more
exaly  

Co-localization of acetylcholinesterase and choline acetyltransferase in the rat cerebrum

Neuroscience, 1983
Allan Levey, Elliott Mufson, B H Wainer   +2 more
exaly  

Choline acetyltransferase-immunoreactive neurons intrinsic to rodent cortex and distinction from acetylcholinesterase-positive neurons

Neuroscience, 1984
Allan Levey, Elliott Mufson, B H Wainer   +2 more
exaly