Results 231 to 240 of about 169,479 (311)

CSF proteomic profiling with amyloid and tau pathology identifies distinctive sex‐specific alteration of multiple proteins involved in Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract INTRODUCTION In Alzheimer's disease (AD), females have higher prevalence and faster progression, but sex‐specific molecular findings in AD are limited. METHODS We comprehensively examined 6162 proteins in cerebrospinal fluid (CSF) from 2496 participants to identify sex‐specific proteomic alteration by CSF amyloid beta (Aβ)42 and phosphorylated
Anh N. Do, Soomin Song, Muhammad Ali, Jigyasha Timsina, Lihua Wang, Daniel Western, Menghan Liu, Jessie Sanford, Matitee Rosende‐Roca, Merce Boada, Raquel Puerta, Edward N. Wilson, Agustin Ruiz, Pau Pastor, the Alzheimer's Disease Neuroimaging Initiative (ADNI), Tony Wyss‐Coray, Carlos Cruchaga, Yun Ju Sung   +17 more
wiley   +1 more source

Temporal Progression of Recognition Memory Impairment, Astrogliosis, and Cholinergic Dysfunction in the Streptozotocin Rat Model of Sporadic Alzheimer's Disease. [PDF]

Int J Mol Sci
Niño-Rivero S, Cabral R, Fleitas J, Alcalde-Ahlig L, Castaño EM, Morelli L, McGregor R, Galeano P, Lagos P.   +8 more
europepmc   +1 more source

Associations between metabolic syndrome and regional brain iron depositions and cognitive function in middle‐aged and older adults: A two multinational cohort study

Alzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract INTRODUCTION The alterations of regional brain iron in patients with metabolic syndrome (Mets) and its relationship with cognitive function remain unclear. METHODS These analyses utilized data from two prospective cohorts, from the UK Biobank (UKB) (21,346 participants) and from Jinan, China (224 participants). We capitalized brain iron in the
Xinyue Zhang, Linfeng Yang, Na Wang, Yuanyuan Wang, Qihao Zhang, Zhenyu Cheng, Yiwen Chen, Pengcheng Liang, Meng Li, Lingfei Guo, Changhu Liang   +10 more
wiley   +1 more source

Non-neuronal cholinergic stimulation favors bone mass accrual. [PDF]

Front Physiol
Tamimi F, Eimar H, Alebrahim S, Abu-Nada L, Manickam G, Al Subaie AE, Tamimi I, Murshed M.   +7 more
europepmc   +1 more source

Heartfelt intervention: A role for PVN oxytocin neurons in the prediabetic heart

The Journal of Physiology, EarlyView.
Grace K. Nielsen, Reesa M. Wilcox, Han‐Jun Wang   +2 more
wiley   +1 more source

Cortically Dependent Motor Training Does Not Induce Abnormal Movements in DYT1‐Knock In Mice

Brain and Behavior, Volume 16, Issue 1, January 2026.
DYT1 dystonia is a familial autosomal dominant, childhood onset dystonia. Mouse models recapitulating the human genotype do not exhibit overtly dystonic movements. It is unclear whether cortically‐dependent tasks are necessary for the development of dystonic movements.
Alexander T. Hodge, Mohammed A. Rasheed, Tiffany Lin, Christian R. Burgess, Daniel K. Leventhal   +4 more
wiley   +1 more source

Donepezil‐Induced Severe Anorexia and T‐Wave Inversion in Early‐Onset Alzheimer's Disease: A Case Report

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Donepezil hydrochloride, used to treat Alzheimer's disease, is typically initiated at a low dose and titrated to minimize gastrointestinal side effects. Despite its favorable safety profile, the patient developed severe anorexia, dehydration, and electrocardiographic abnormalities.
Nobuyuki Takahashi, Takeshi Kuroda, Takashi Yoshioka, Hidetomo Murakami, Hironori Tanaka   +4 more
wiley   +1 more source

A Whiff of Garlic, a Turn of Fate: Recognizing Organophosphorus Poisoning Amid Diagnostic Uncertainty: A Case Report

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT OP compounds, commonly used as pesticides, are readily available over the counter and frequently implicated in intentional poisoning. We report a case of a 43‐year‐old male with OP poisoning initially misdiagnosed as alcohol intoxication. He was intubated in the emergency department on arrival due to a low Glasgow Coma Scale (GCS) of 6/15 and ...
Sujan Tamang, Bishwo Ram Amatya, Sulav Neupane, Sunischit Chandra Neupane, Chiranjivi Panta, Anusmriti Pal, Dipesh Shrestha   +6 more
wiley   +1 more source