Prediabetic cardiomyopathy is attenuated by hypothalamic PVN oxytocin neuron activation
Abstract figure legend A long‐term high‐fat, high‐fructose diet induces prediabetes with insulin resistance, hyperinsulinaemia, elevated triglycerides and metabolic‐associated steatotic liver disease (MASLD) in male rats. Animals developed prediabetic cardiomyopathy characterized by diastolic dysfunction, interstitial fibrosis and tachycardia ...
Anna Nilsson +7 more
wiley +1 more source
Chronic Administration of <i>Calendula officinalis</i> Ethanolic Extract Mitigates Anxiety-like Behavior and Cognitive Impairment Induced by Acute Scopolamine Exposure in Zebrafish. [PDF]
Popovici LF +3 more
europepmc +1 more source
Dual cholinergic and serotonergic excitatory pathways mediate oxygen sensing in the zebrafish gill
Abstract figure legend The present study identified two sub‐populations of gill oxygen sensing neuroepithelial cells (NECs) distinguishable by their stored neurotransmitters – serotonin (5‐hydroxytryptamine, 5‐HT) or acetylcholine (ACh). Using transgenic Tg(elavl3:GCaMP6s) zebrafish, which express an endogenous calcium reporter in neurons, we ...
Maddison Reed +3 more
wiley +1 more source
Alcohol addiction and Alzheimer's disease: a molecular collision course. [PDF]
Chang JS +6 more
europepmc +1 more source
Intrinsic mechanisms contributing to the biophysical signature of mouse gamma motoneurons
Abstract figure legend In this study, we identify key intrinsic properties underlying the distinct biophysical signature of gamma motoneurons (blue): a motoneuron subtype that innervates intrafusal muscle fibres (orange) to adjust spindle afferent (black) sensitivity for detecting muscle length changes during movement.
Simon A. Sharples +6 more
wiley +1 more source
Mulberroside A: A Multi-Target Neuroprotective Agent in Alzheimer's Disease via Cholinergic Restoration and PI3K/AKT Pathway Activation. [PDF]
Li J +9 more
europepmc +1 more source
Cholinergic changes in Lewy body disease: implications for presentation, progression and subtypes
Niels Okkels +10 more
openalex +2 more sources
The medial septum-hippocampus-lateral septum circuitry in spatial memory: linking healthy function to early Alzheimer's disease and translational opportunities. [PDF]
Song Y, Ni J, Qing H, Quan Z.
europepmc +1 more source
A cholinergic spinal pathway for the adaptive control of breathing. [PDF]
Lin M +9 more
europepmc +1 more source

