Results 91 to 100 of about 51,688 (341)

Review of nutrition management of pediatric intestinal pseudo‐obstruction

open access: yesNutrition in Clinical Practice, EarlyView.
Abstract Chronic intestinal pseudo‐obstruction (CIPO) is a rare, heterogeneous, and debilitating disorder characterized by profound intestinal dysmotility and severe nutrition challenges. Its presentation resembles that of mechanical bowel obstruction, but CIPO occurs in the absence of luminal obstruction.
Senthilkumar Sankararaman   +5 more
wiley   +1 more source

Neuroprotective effects of ursodeoxycholic acid in Parkinson's disease and Alzheimer's disease

open access: yesNeuroprotection, EarlyView.
In Parkinson's disease (PD) and Alzheimer's disease (AD), various shared pathological mechanisms exist. UDCA has been shown to exert neuroprotective effects in preclinical and clinical studies. Such effects include the mitigation of neuroinflammation as well as rescue effects on mitochondrial dysfunction, oxidative stress, impaired autophagy, and ...
Ashley En Yi Chong   +3 more
wiley   +1 more source

Comparison of Different Neostigmine Doses for Reversal of Cisatracurium‐Induced Neuromuscular Block in Children Under Total Intravenous Anesthesia: A Randomized Controlled Trial

open access: yesPediatric Anesthesia, EarlyView.
ABSTRACT Background Neostigmine is widely used to reverse nondepolarizing neuromuscular blockade in children, but the optimal dose under total intravenous anesthesia is uncertain. Aims The primary aim was to compare the time to full neuromuscular recovery (TOF ratio of 1.0) following administration of neostigmine at doses of 0, 10, 20, and 30 μg/kg in ...
Antonio J. M. M. Neto   +7 more
wiley   +1 more source

Identification of broadly expressed nervous system‐related genes as effective RNAi targets in the brown marmorated stink bug, Halyomorpha halys

open access: yesPest Management Science, EarlyView.
Broadly expressed genes outperformed brain‐enriched neural targets as RNAi candidates in Halyomorpha halys. Microinjection of dsRNA targeting alpha‐soluble NSF attachment protein (Asnap) or Ras opposite protein (Rop) caused strong feeding suppression and near‐complete mortality, identifying them as promising targets for future oral or spray‐based RNAi ...
Nirakar Panda   +2 more
wiley   +1 more source

Nociceptor α7nAChR activation blunts neuronal HMGB1 release and attenuates inflammation and nociceptive behavior

open access: yesMolecular Medicine
Background High Mobility Group Box 1 (HMGB1) is a nuclear protein that upon extracellular release acts as an alarmin to initiate and amplify inflammation.
Huan Yang   +10 more
doaj   +1 more source

Calcium mediation of cholinergic-stimulated amylase release from mouse parotid gland

open access: yes, 1979
Amylase release from mouse parotid fragments was stimulated independently by cholinergic and beta-adrenergic agents. The cholinergic agonist, carbachol, significantly increased release of amylase only in Ca2+ containing medium whereas isoproterenol ...
I. A. Siegel   +2 more
core   +1 more source

Oxidative Damage, Energy Imbalance, and Behavioral Disruptions in Girardia tigrina Exposed to Treated Sewage Effluents

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT This study assessed the ecotoxicological effects of treated sewage on the freshwater planarian Girardia tigrina, integrating biochemical, energetic, and behavioral biomarkers. Planarians were exposed for 48 h to different concentrations of treated sewage (12.5%, 25%, 50%, and 100%) and compared to controls using commercial water and water from
Renata M. P. Freitas   +3 more
wiley   +1 more source

Modulation of presynaptic cholinergic mechanisms by volatile anaesthetic agents.

open access: yes, 1971
The effects of volatile anaesthetic agents on three aspects of presynaptic acetylcholine (ACh) metabolism were investigated in vitro. Choline uptake and choline acetyltransferase (ChAT) activity were studied using rat cortical synaptosomes and ACh ...
Richard E. Griffiths (7703090)
core  

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