ORIGIN OF THE CHOLINERGIC RESPONSE OF THE RABBIT INTESTINE TO STIMULATION OF ITS EXTRINSIC SYMPATHETIC NERVES AFTER EXPOSURE TO SYMPATHETIC BLOCKING AGENTS [PDF]
G. BOYD, J. S. GILLESPIE, B.R. Mackenna
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Avaliação dos efeitos tóxicos induzidos por malation e malaoxon e a possível proteção por oximas [PDF]
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Bioquímica, Florianópolis, 2013O malation é um composto tóxico pertencente à classe dos pesticidas organofosforados (OF) que tem como ...
Santos, Alessandra Antunes dos
core
GIP in Cardiovascular and Kidney Disease: From Physiology to Pharmacology
ABSTRACT Aims To provide a comprehensive overview of the cardiovascular and renal effects of glucose‐dependent insulinotropic polypeptide (GIP) by integrating its physiological role with recent human trial data on tirzepatide, the first dual GIP and glucagon‐like peptide‐1 (GLP‐1) receptor agonist.
Michelantonio De Fano +4 more
wiley +1 more source
Recent Advances in the Treatment of Organophosphorous Poisonings [PDF]
Organophosphorous compounds have been employed as pesticides and chemical warfare nerve agents. Toxicity of organophosphorous compounds is a result of excessive cholinergic stimulation through inhibition of acetyl cholinesterase.
Mahdi Balali-Mood, Hamidreza Saber
doaj
Summary Alpha‐2‐adrenoreceptor agonists provide analgesia when used as sole agents but can also be used in combination with other drugs for their additive and potentially synergistic effects. Further, because of their effects on blood flow, alpha‐2‐adrenoreceptor agonists act to extend and perhaps intensify the effects of drugs, such as local ...
J. Brandly +4 more
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Microelectrophoretic Application of Cholinergic Compounds, Protein Oxidizing Agents, and Mercurials to the Chemically Excitable Membrane of the Electroplax [PDF]
J. del Castillo +2 more
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Response of Urinary Bladder to Cholinergic and Adrenergic Agents
The pharmacologic response of bladder muscle strip of albino rabbits was studied in vitro. The effect of cholinergic and adrenergic agents and their antagonists were demonstrated with a log dose-response curve.
KONDO, ATSUO
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Evolving treatments for Sjögren disease: current approaches and emerging targets
Abstract Sjögren disease (SjD) is a prevalent systemic autoimmune condition characterised by exocrine gland dysfunction, systemic inflammation and heterogeneous organ involvement. Current management remains largely symptomatic, with no approved disease‐modifying therapies available and substantial unmet clinical need. However, advances in understanding
Mansi Bhurani +3 more
wiley +1 more source
Ocular surface alterations in agricultural workers exposed to pesticides in Cundinamarca, Colombia
Background: The cholinergic system regulates a variety of structures on the ocular surface and maintains homeostasis. Therefore, dysregulation of cholinergic activity could impact lacrimal and conjunctival function.
Yuly-N. Franco +5 more
doaj +1 more source
Pathophysiology and emerging treatments for dermographic, cholinergic and cold urticaria
This review illustrates key proposed mast cell‐mediated activation pathways in dermographic, cholinergic and cold urticaria, highlighting IgE‐dependent and ‐independent mechanisms. These pathways are increasingly targeted by emerging drugs, aiming to interrupt mast cell activation and mediator release, offering more precise, mechanism‐based treatment ...
Mojca Bizjak‐Suran +2 more
wiley +1 more source

