Results 111 to 120 of about 51,688 (341)

Avaliação dos efeitos tóxicos induzidos por malation e malaoxon e a possível proteção por oximas [PDF]

open access: yes, 2013
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Bioquímica, Florianópolis, 2013O malation é um composto tóxico pertencente à classe dos pesticidas organofosforados (OF) que tem como ...
Santos, Alessandra Antunes dos
core  

GIP in Cardiovascular and Kidney Disease: From Physiology to Pharmacology

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To provide a comprehensive overview of the cardiovascular and renal effects of glucose‐dependent insulinotropic polypeptide (GIP) by integrating its physiological role with recent human trial data on tirzepatide, the first dual GIP and glucagon‐like peptide‐1 (GLP‐1) receptor agonist.
Michelantonio De Fano   +4 more
wiley   +1 more source

Recent Advances in the Treatment of Organophosphorous Poisonings [PDF]

open access: yesIranian Journal of Medical Sciences, 2012
Organophosphorous compounds have been employed as pesticides and chemical warfare nerve agents. Toxicity of organophosphorous compounds is a result of excessive cholinergic stimulation through inhibition of acetyl cholinesterase.
Mahdi Balali-Mood, Hamidreza Saber
doaj  

Analgesic effects of alpha‐2‐adrenoreceptor agonists in equine medicine: systemic, spinal, and local applications

open access: yesEquine Veterinary Education, EarlyView.
Summary Alpha‐2‐adrenoreceptor agonists provide analgesia when used as sole agents but can also be used in combination with other drugs for their additive and potentially synergistic effects. Further, because of their effects on blood flow, alpha‐2‐adrenoreceptor agonists act to extend and perhaps intensify the effects of drugs, such as local ...
J. Brandly   +4 more
wiley   +1 more source

Response of Urinary Bladder to Cholinergic and Adrenergic Agents

open access: yes
The pharmacologic response of bladder muscle strip of albino rabbits was studied in vitro. The effect of cholinergic and adrenergic agents and their antagonists were demonstrated with a log dose-response curve.
KONDO, ATSUO
core  

Evolving treatments for Sjögren disease: current approaches and emerging targets

open access: yesInternal Medicine Journal, EarlyView.
Abstract Sjögren disease (SjD) is a prevalent systemic autoimmune condition characterised by exocrine gland dysfunction, systemic inflammation and heterogeneous organ involvement. Current management remains largely symptomatic, with no approved disease‐modifying therapies available and substantial unmet clinical need. However, advances in understanding
Mansi Bhurani   +3 more
wiley   +1 more source

Ocular surface alterations in agricultural workers exposed to pesticides in Cundinamarca, Colombia

open access: yesJFO Open Ophthalmology
Background: The cholinergic system regulates a variety of structures on the ocular surface and maintains homeostasis. Therefore, dysregulation of cholinergic activity could impact lacrimal and conjunctival function.
Yuly-N. Franco   +5 more
doaj   +1 more source

Pathophysiology and emerging treatments for dermographic, cholinergic and cold urticaria

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
This review illustrates key proposed mast cell‐mediated activation pathways in dermographic, cholinergic and cold urticaria, highlighting IgE‐dependent and ‐independent mechanisms. These pathways are increasingly targeted by emerging drugs, aiming to interrupt mast cell activation and mediator release, offering more precise, mechanism‐based treatment ...
Mojca Bizjak‐Suran   +2 more
wiley   +1 more source

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