Results 101 to 110 of about 51,688 (341)

Taxon, Arboreality, Sex, and Season—Factors Influencing Gastrointestinal Parasite Occurrence in Zoo‐Housed Non‐Human Primates

open access: yesZoo Biology, EarlyView.
ABSTRACT The emergence of anthelminthic resistance is a well‐documented phenomenon in livestock and companion animals. Given the scarcity of new antiparasitic drugs, the implementation of effective, holistic anthelminthic control strategies is critical to preserving the efficacy of existing treatments.
Stalder Sandro, Hatt Jean‐Michel
wiley   +1 more source

Increased cholinergic contractions of jejunal smooth muscle caused by a high cholesterol diet are prevented by the 5-HT4 agonist – tegaserod

open access: yesBMC Gastroenterology, 2006
Background Excess cholesterol in bile and in blood is a major risk factor for the respective development of gallbladder disease and atherosclerosis. This lipid in excess negatively impacts the functioning of other smooth muscles, including the intestine.
Shaffer Eldon, Mathison Ronald
doaj   +1 more source

A review of the relationship between dimensions of alcohol consumption and the burden of disease: 2026 update including Mendelian randomisation studies

open access: yesAddiction, EarlyView.
Abstract Background and aims Evidence on the causal impact and corresponding risk relationships between dimensions of alcohol consumption and health outcomes continues to evolve, with some contradictory findings across study designs. This review aimed to update current knowledge on causality and risk relationships to inform global and national ...
Sinclair Carr   +5 more
wiley   +1 more source

Defining a role for the peduncolopontine tegmental nucleus in striatal outflow

open access: yes, 2012
The pedunculopontine tegmental nucleus (PPTg) lies within the pontomesencephalon and contains cholinergic and non-cholinergic neurones. It has extensive afferent and efferent connections throughout the brain.
Allen, Laura F.
core  

The International Guideline for the Definition, Classification, Diagnosis and Management of Urticaria

open access: yesAllergy, EarlyView.
ABSTRACT This update and revision of the international guideline for urticaria was developed in accordance with the methods recommended by Cochrane and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) working group. It is an initiative of the Global Allergy and Asthma Excellence Network (GA2LEN) and its Urticaria and ...
T. Zuberbier   +221 more
wiley   +1 more source

Endothelium‐ and epithelium‐derived novel endogenous catecholamines as modulators of the autonomic nervous system

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Catecholamines are classically viewed as neuronal transmitters and adrenal hormones; however, accumulating evidence demonstrates that sources other than nerve fibres and adrenal medulla play a fundamental role in local organ regulation. Physiological paradoxes, such as preserved organ function after denervation or transplantation, challenge a ...
Mariana G. de Oliveira   +3 more
wiley   +1 more source

Immediate early gene expression in the mesopontine tegmentum and midbrain after acute or chronic nicotine administration

open access: yes, 2008
The reinforcing properties of nicotine depend partly on cholinergic projections from the pedunculopontine tegmental (PPTg) and laterodorsal tegmental (LDTg) nuclei to midbrain dopamine neurons in the ventral tegmental area (VTA) and substantia nigra pars
Porter, Ailsa
core  

Alteration of adrenergic responses by chronic cholinergic blockade

open access: yes, 1960
The effect of the chronic administration of cholinergic blocking agents on the secretory and cardiovascular responses to epinephrine, levarterenol and isoproterenol has been determined in the dog.
David C. Jerram
core   +1 more source

Inhibition of peripheral CB1 receptors modulates food intake and metabolic efficiency in obesity independently of the gut–brain vagal axis

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Obesity involves profound disruptions in neuronal circuits, neuroendocrine communication and the endocannabinoid system. While global blockade of cannabinoid CB1 receptors improves metabolism, its clinical use is limited by neuropsychiatric side effects.
Oriane Onimus   +7 more
wiley   +1 more source

New Heterostilbene and Triazole Oximes as Potential CNS-Active and Cholinesterase-Targeted Therapeutics

open access: yesBiomolecules
New furan, thiophene, and triazole oximes were synthesized through several-step reaction paths to investigate their potential for the development of central nervous systems (CNS)-active and cholinesterase-targeted therapeutics in organophosphorus ...
Milena Mlakić   +4 more
doaj   +1 more source

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