Results 191 to 200 of about 51,688 (341)

The Effect of Sugammadex Versus Neostigmine on Postoperative Cognitive Recovery: A Systematic Review and Meta-Analysis. [PDF]

Cureus
Martins de Brito H, Ferraz Pozzer Gularte D, de Queiroz Vasconcelos V, Willamy Pedrosa Alves Filho F, Alves Lima N, Lynn Sabartinelli Stein A, de Almeida Macruz T.   +6 more
europepmc   +1 more source

Progress of Immunotherapies in Parkinson's Disease

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
Parkinson's disease (PD) is caused by an immune disorder triggered by α‐synuclein, leading to a persistent neuroinflammatory cycle that drives the disease from non‐motor symptoms to the motor stage. Second, it presents active and passive immunotherapy strategies targeting α‐synuclein and their potential in slowing down the disease progression.
Yong Peng, Xu‐hui Kang, Shun‐yu Yao, Xiuli Zhang, Sugimoto Kazuo, Jia Liu, Miao‐qiao Du, Lan‐xin Lin, Dai‐yi Jiang, Quan Chen, Hong Jin   +10 more
wiley   +1 more source

Exploring the Evolving Role of Scopolamine in Pharmacotherapy: From Cognitive Impairment to Neuroplasticity?-A Narrative Review. [PDF]

Molecules
Kukla J, Olejnik P, Kasarełło K.
europepmc   +1 more source

Central Cholinergic Agents. I. Potent Acethlcholinesterase Inhibitors, 2-(.OMEGA.-(N-Alkyl-N-(.OMEGA.-phenyl-alkyl)amino)alkyl)-1H-isoindole-1,3(2H)-diones, Based on a New Hypothesis of the Enzyme's Active Site.

, 1991
Yuji ISHIHARA, Koki KATO, Giichi Goto
openalex   +2 more sources

Ocular Adverse Events Associated With Antidepressants: A Large‐Scale Data Analysis From the FAERS Database

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
This decadal FAERS study (2015–2024) identifies 62,020 ocular adverse events (AEs) across 39 antidepressants, highlighting ocular neuromuscular disorders as a key risk. NDDIs show the strongest associations, while SSRIs exhibit the broadest signal spectrum.
Yiming Peng, Yichen Cao, Hanhan Liu, Junlong Ma, Guoping Yang   +4 more
wiley   +1 more source

Neurotransmitter-Mediated Signaling in Glioblastoma and Glial Tumors: Biology and Therapeutic Opportunities. [PDF]

Oncol Res
Tralongo P, Ballato M, Zuccalà V, Fiorentino V, Giordano W, Casili G, Bellinghieri F, Caruso G, Angileri FF, Fadda G, Martini M, Caffo M.   +11 more
europepmc   +1 more source

Early exposure to a cholinergic receptor blocking agent mitigates adult obesity and protects pancreatic islet function in male rats

Ananda Malta, Camila Cristina Ianoni Matiusso, Lucas da Silva de Lima, Tatiane Aparecida Ribeiro, Laize Peron Tófolo, Douglas Lopes Almeida, Veridiana Mota Moreira, Isabela Peixoto Martins, Audrei Pavanello, Paulo Cézar de Freitas Mathias   +9 more
openalex   +1 more source

Tramiprosate, the Active Agent of ALZ‐801, Modulates Amyloidogenic APP Processing and Tau Phosphorylation in a Cellular Model of Alzheimer's Disease

Drug Development Research, Volume 87, Issue 4, June 2026.
ABSTRACT ALZ‐801, a valine‐conjugated prodrug of tramiprosate, has recently been evaluated in a Phase III trial as a potential Alzheimer's disease (AD)‐modifying therapy. Tramiprosate reduces misfolding of amyloid beta (Aβ) monomers and inhibits oligomer formation. In the present study, we investigated tramiprosate's effects on amyloidogenic processing
Kevser Biberoglu, Ozden Tacal
wiley   +1 more source

Gomisin E attenuates pentobarbital-induced sleep deficits in aging-related insomnia: an <i>in vivo</i> and <i>in silico</i> study implicating cholinergic signaling. [PDF]

Front Psychol
Yang F, Jiang F, Li X.
europepmc   +1 more source

Bibliometric Analysis of Cubebenes and Related Sesquiterpenes: Natural Occurrence, Biosynthesis, Pharmacological Activities, and In‐Silico‐Based Future Therapeutic Potential

eFood, Volume 7, Issue 3, June 2026.
Cubebene‐related sesquiterpenes, found across diverse biological sources, exhibit promising pharmacological activities, including anti‐inflammatory, neuroprotective, and anticancer effects. This review highlights their molecular diversity, ADME profiles, and predicted multitarget interactions, underscoring their therapeutic relevance and potential in ...
Khadija Boualam, Ahmet B. Ortaakarsu, Sohaib Khatib, Mohamed A. Farag, Mansour Sobeh   +4 more
wiley   +1 more source