Results 181 to 190 of about 51,688 (341)

Central Cholinergic Agents. 6. Synthesis and Evaluation of 3-[1-(Phenylmethyl)-4-piperidinyl]-1-(2,3,4,5-tetrahydro-1H-1-benzazepin-8-yl)- 1-propanones and Their Analogs as Central Selective Acetylcholinesterase Inhibitors

, 1994
Yuji Ishihara, Keisuke Hirai, Masaomi Miyamoto, Giichi Goto   +3 more
openalex   +1 more source

MOLECULAR. REQUIR.EMENTS OF THE ACTIVE SITESOF THE CHOLINERGIC RECEPTORS

, 1982
Some cyclopentene derivatives lacking the oxygenatedlunctions have been sltnthesized and tested as cholinergic compounds. Theirgood muscarinic potency seems to confirm that such compounds interactwith a receptor area which is not coincident with that ...
M. LEONELLI, BRASILI, Livio, M. GIANNELLA   +2 more
core  

Monoamine Oxidase and Cholinesterase Inhibition Profiles of Semicarbazone and Thiosemicarbazone Derivatives

Chemistry &Biodiversity, Volume 23, Issue 6, June 2026.
Thiosemicarbazones generally show higher MAO‐B inhibitory potential than their corresponding semicarbazones, and particularly T6 is the most potent, which contains R = H and X = S in its Tail Unit, with an IC50 value of 6.45 µM with SI of 3.6. ABSTRACT Twenty semicarbazone and thiosemicarbazone derivatives (T1–T20) were synthesized and evaluated for ...
Sandeep Bindra, Won Kyeong Jeong, Muzammil Kabier, Sunil Kumar, Sachithra Thazhathuveedu Sudevan, Harish Chandra vishwakarma, Della Grace Thomas Parambi, Naseer Maliyakkal, Sandeep Kumar, Leena K. Pappachen, Hoon Kim, Bijo Mathew   +11 more
wiley   +1 more source

Topical pyridostigmine for ocular myasthenia gravis: a translational hypothesis. [PDF]

Med Hypothesis Discov Innov Ophthalmol
Ing EB, Lim K, Davies NM, Lobenberg R, Harunur Rashid M, Le TS, Rullo J.   +6 more
europepmc   +1 more source

In Vivo Direct Effects of Cholinergic Agents on the Inferior Mesenteric and Cardiac Ganglia with Relation to Their Receptors in the Dog

, 1979
Kazushi Kushiku, Seiichi Ichimasa, Hiro‐o Kamiya, Tatsuo Furukawa   +3 more
openalex   +1 more source

Deciphering Antidiabetic, Anti‐Inflammatory, and Anti‐Cholinergic Bioactivities of Withania somnifera (L) Dunal Root Extract: An In Vitro and In Silico Investigation

Chemistry &Biodiversity, Volume 23, Issue 6, June 2026.
In this investigation, Withania somnifera root ethanol extract displays anti‐inflammatory and antidiabetic properties. Though compounds including withasomniferolide B and sitoindoside IX have been previously identified as phytoconstituents in the plant, in silico analysis from this study revealed them as new lead compounds that could act as potential ...
Lufuno Mulelu, Jacqueline N. Manjia, Kolawole A. Olofinsan, Londiwe Xulu, Motlalepula G. Matsabisa   +4 more
wiley   +1 more source

Seizure and Status Epilepticus in Human Organophosphate Poisoning: A Narrative Review. [PDF]

Neurol Int
Magro G, Marsico O, Tosto F, Lobianco C, Rapisarda L, Mastroianni G, Pascarella A.   +6 more
europepmc   +1 more source

Determination of bicarbonate output using pH deflection in the rat duodenum: Influences of prostaglandins and cholinergic agents.

, 1990
Koji Takeuchi, Hiromichi Niida, Masashi Minami, Susumu Okabe   +3 more
openalex   +1 more source

The role of cholinergic agents in the management of behavioural disturbances in Alzheimer's disease [PDF]

, 2000
Jeffrey L. Cummings
openalex   +1 more source

Proline‐Rich Transmembrane Protein 2 Is Variably Expressed Across Excitatory and Inhibitory Neurons in Mouse Motor Circuits

Journal of Comparative Neurology, Volume 534, Issue 6, June 2026.
Prrt2, a causal gene for paroxysmal kinesigenic dyskinesia, was sparsely expressed in nigrostriatal dopaminergic neurons, but alternatively in excitatory (within the cerebral cortex and cerebellum) or inhibitory (within the basal ganglia) neurons in a region‐dependent manner, suggesting that Prrt2 functions in both the basal ganglia and cerebellar ...
Daisuke Hatta, Kaori Watanabe, Akira Kinoshita, Koh‐Ichiro Yoshiura, Naohiro Kurotaki, Keiro Shirotani, Nobuhisa Iwata   +6 more
wiley   +1 more source