Results 161 to 170 of about 51,688 (341)
Pharmacological Incongruity of Lacosamide in the Management of Delirium Complicated by Ileus. [PDF]
Neuropsychopharmacol RepDelirium involves neurotransmitter imbalances and disrupted neural networks. Although lacosamide may theoretically treat delirium by reducing neuronal hyperexcitability via sodium channel modulation, clinical evidence is lacking. Sodium channels in the enteric nervous system mean lacosamide can cause gastrointestinal dysmotility independent of ...
Nagamine T.
europepmc +2 more sources
Acid and pepsin secretion of separated gastric pouches during perfusion of antral pouches with cholinergic stimulating and blocking agents and lignocaine. [PDF]
, 1977 L. Μ. McLeay, D. A. Titchen
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ChemMedChem, Volume 21, Issue 11, 15 June 2026.In this work, we identified two novel pleiotropic sinapic acid derivatives with excellent anti‐acetylcholinesterase, antioxidant, and anti‐inflammatory properties. Alzheimer's disease, one of the most widespread neurodegenerative disorders, is known for its multifactorial nature that makes it challenging to treat.
Konstantina Sdougkou +2 more
wiley +1 more source
An investigation into cholinergic interactions in the rat pineal gland
, 1993 The mammalian pineal gland is mainly innervated by the sympathetic nervous system which modulates the activity of indole pathway enzymes and the secretion of pineal hormones.
Eason, Jason Shane
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Advanced Science, Volume 13, Issue 32, 9 June 2026.Phospholipase A2 (PLA2), a dormant enzyme, becomes lethal when activated—collapsing lungs in minutes. Our dual therapy (DOPS + varespladib) boosts survival from 0% to >90% in sepsis/ALI. A breakthrough for acute lung injury treatment. ABSTRACT This study reveals that phospholipase A2 (PLA2), normally stable and nontoxic, can be activated specifically ...
Jianyu Wang +7 more
wiley +1 more source
Corrigendum: Deepening insights into cholinergic agents for intraocular pressure reduction: systems genetics, molecular modeling, and in vivo perspectives. [PDF]
Front Mol BiosciKim MJ, Ibrahim MM, Jablonski MM.
europepmc +1 more source
Kinetic response of a membrane‐bound acetylcholinesterase to cholinergic activating and blocking agents [PDF]
, 1970 Andrej O. Župančič
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Advanced Science, Volume 13, Issue 34, 19 June 2026.Despite widespread exposure, the mechanisms of manganese neurotoxicity remain poorly understood. Using correlative cryogenic fluorescence and synchrotron X‐ray fluorescence imaging techniques, we show that the Golgi apparatus is the primary accumulation site for manganese in both neurons and astrocytes, and that manganese targets the neuronal ...
Ines Kelkoul +12 more
wiley +1 more source
Cholinergic Muscarinic Receptor: Biochemical and Light Autoradiographic Localization in the Brain
, 1975 The muscanmc cholinergic antagonist 3-quinudidinyl benzilate (QNB) binds avidly but reversibly to the muscarinic cholinergic receptor of mammalian brain and peripheral tissues.
Henry I. Yamamura +7 more
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