Results 171 to 180 of about 51,688 (341)

Redirecting Alzheimer's disease therapeutics: Multitarget drugs and complementary non‐pharmacological strategies

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder driven by intersecting pathological processes. Persistent attrition in AD drug‐development pipelines highlights the limited clinical impact of single‐target therapies and has increased interest in multi‐target approaches acting on shared biological hubs.
Humberto Martínez‐Orozco, Jesús Andrade‐Guerrero, Nelly Jovana Pastén‐Castrejón, Chryslaine Rodríguez‐Tanty, Sofía Y Diaz‐Miranda   +4 more
wiley   +1 more source

Sleep Disturbances Among Yazidi Survivors of the ISIS Genocide: Epidemiology, Neuropsychology, and Culturally Sensitive Interventions

Brain and Behavior, Volume 16, Issue 6, June 2026.
The figure presents an integrative model of sleep disturbances among Yazidi survivors of the 2014 genocide perpetrated by the Islamic State (ISIS). Genocide‐related trauma, including mass violence, sexual violence, displacement, and historical trauma, is associated with sustained neurobiological dysregulation, including hypothalamic–pituitary–adrenal ...
Jan Ilhan Kizilhan, Zelal Ag, Qanta A. Ahmed, Alon Y. Avidan   +3 more
wiley   +1 more source

Caffeine and Headache: Exploring the Multifaceted Relationship

Brain and Behavior, Volume 16, Issue 6, June 2026.
ABSTRACT Purpose To explore the multifaceted relationship between caffeine and headache disorders, focusing on its dual role as both an analgesic and a potential trigger and to summarize the mechanisms underlying its anti‐nociceptive effects. Method This narrative review synthesizes evidence from experimental, clinical, and epidemiological studies on ...
Mona Hussein, Amr Hassan, Salsabil Abo Al‐Azayem, Janu Thuraiaiyah, Henrik Winther Schytz, Anter Mothenna Abdullah Nasser, Rehab Magdy   +6 more
wiley   +1 more source

Conceptual Rationale for Combining Galantamine, Iontophoresis, and Black Sea Brine in Peripheral Neuropathy: A Narrative Review. [PDF]

NeuroSci
Ivanova M, Panayotova-Ovcharova L, Nedyalkova-Petkova D, Petkov P, Boshev G, Vladeva E.   +5 more
europepmc   +1 more source

The Direct Cholinomimetics and Cholinergic Blocking Agents Depend on Stereo Specificity of Cholinergic Receptors

Rezk R. Ayyad, Ahmed M. Mansour, Ahmed M. Nejm, Yasser Abdel Allem Hassan, Ahmed R. Ayyad   +4 more
openalex   +2 more sources

Response of guinea pig ileum and atria to cholinergic agents following administration of an organophophorus compound

, 1977
Eiichi Hayashi, Kazuhiko Gohshi, Osamu Sasaki, Shizuo Yamada   +3 more
openalex   +1 more source

Neurocognitive Aging Following Acute Illness: Pathobiology and a Framework for Developing Neurotherapeutic Agents

Brain and Behavior, Volume 16, Issue 6, June 2026.
In this review, we discuss the scientific basis for how neurocognitive aging occurs after critical illness, including sepsis, trauma, and burns, and the clinical need to develop therapies to reduce inflammation, protect the blood–brain barrier, remove senescent cells, and enhance neuroplasticity.
Errin Lawrence, Daniel Fulton, Poppy Brown, Subashini Suresh, Mark Morris, Paraskevi Goggolidou, Sree Chaithanya, Marcus Abbawy, Amelia Wild, Prashant Nasa, Niharika A. Duggal, Fang Gao‐Smith, Zubair Ahmed, Suresh Renukappa, Tonny Veenith   +14 more
wiley   +1 more source

Herbal Neurotherapeutics for Cognitive Disorders: Integrative Mechanisms Linking Neurotransmitter Systems, Neurodegeneration, and the Gut-Brain Axis. [PDF]

Nutrients
Rahman M, Akter K, Rani A, Park MN, Kim B.   +4 more
europepmc   +1 more source

Evolving Trends and Collaborative Networks in Postoperative Delirium Research: A Two‐Decade Bibliometric Analysis

Brain and Behavior, Volume 16, Issue 6, June 2026.
This bibliometric study analyzes 1,937 POD articles from 65 countries, with annual publications accelerating markedly after 2019. China leads in publication volume, while the US tops citations and holds stronger centrality in the international collaboration network. Four major research domains are identified: characteristics, mechanisms, prediction and
Kehan Wang, Cheng Xu, Yuan Zhu, Quanhong Zhou, Tao Xu   +4 more
wiley   +1 more source

L-α-GPC in Cognitive Decline: Mechanisms and Clinical Evidence in Neurodegenerative Disorders. [PDF]

Neuropsychiatr Dis Treat
Putri VA, Hapsari RS, Amalia R.
europepmc   +1 more source