Results 91 to 100 of about 176,034 (239)

Cholinergic antagonists block contralateral suppression of distortion product otoacoustic emissions.

open access: yes, 1993
Presentation of an acoustic signal to one ear can suppress sound-evoked activity recorded at the opposite ear. The suppression appears to be mediated by uncrossed medial olivocochlear (MOC) efferent neurons synapsing with cochlear outer hair cells (OHCs).
Kujawa, Sharon Guilds.
core   +4 more sources

Cholinergic neurons in the dorsomedial hypothalamus regulate mouse brown adipose tissue metabolism

open access: yesMolecular Metabolism, 2015
Objective: Brown adipose tissue (BAT) thermogenesis is critical in maintaining body temperature. The dorsomedial hypothalamus (DMH) integrates cutaneous thermosensory signals and regulates adaptive thermogenesis.
Jae Hoon Jeong   +7 more
doaj   +1 more source

Emergencies in Amyotrophic Lateral Sclerosis

open access: yesMuscle &Nerve, EarlyView.
ABSTRACT Emergencies are frequent in people living with amyotrophic lateral sclerosis (pALS), especially as the disease progresses, and can necessitate urgent evaluation and intervention. Progressive weakness in ALS inevitably increases fall risk, making discussion of fall prevention strategies integral to caring for pALS.
S. Pinar Uysal   +9 more
wiley   +1 more source

Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges

open access: yesNeuroprotection, EarlyView.
Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi   +5 more
wiley   +1 more source

Breaking Alzheimer's Disease Barrier: The Role of Xanthoceras sorbifolia Bunge Oil in Gut‐Brain Axis and TLR4/Myd88/MAPK Pathway Inhibition

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative disorder associated with cognitive decline and neuroinflammation. Xanthoceras sorbifolia Bunge oil (XSBO), a woody plant oil rich in bioactive fatty acids, has shown potential health benefits.
Lijing Du   +8 more
wiley   +1 more source

Cooperative Glutamatergic and Cholinergic Mechanisms Generate Short-Term Modifications of Synaptic Effectiveness in Prepositus Hypoglossi Neurons [PDF]

open access: yes, 2005
To maintain horizontal eye position on a visual target after a saccade, extraocular motoneurons need a persistent (tonic) neural activity, called "eye-position signal," generated by prepositus hypoglossi (PH) neurons.
Navarro Lopez, JDD   +2 more
core  

VGCC antagonists modify the acute Zn2+ neurotoxic effects on K+ depolarized SN56 cholinergic neuroblastoma cells.

open access: yes, 2018
VGCC antagonists modify the acute Zn2+ neurotoxic effects on K+ depolarized SN56 cholinergic neuroblastoma cells.
Adam Iwanicki (553559)   +8 more
core   +1 more source

An unusual case of altered sensorium in a young child: Datura poisoning

open access: yesCHRISMED Journal of Health and Research, 2014
Datura stramonium (DS) is a wildly growing plant which is widely distributed and easily accessible. It contains a variety of toxic anticholinergic alkaloids such as atropine, hyoscamine, and scopolamine.
Bindu T Nair   +2 more
doaj   +1 more source

Pharmacokinetic and Pharmacodynamic Interactions Between Anti‐Asthma Drugs and Medicinal Plants: A Comprehensive Review

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Asthma affects 260–300 million people worldwide. About 20%–35% of patients use medicinal plants with their asthma medication, often without telling their clinicians. Disclosure rates are low; up to 42% of asthma outpatients use herbal products, with no records in their charts.
Emine Kocyigit   +5 more
wiley   +1 more source

Purinergic receptor expression in neuronal, bladder smooth muscle and urothelial cells: characterization and inhibition by low molecular weight antagonists [PDF]

open access: yes, 2009
P2 purinoceptors comprise ionotropic (P2X) and metabotropic (P2Y) receptor families, responsive to nucleotide ligands and diversely distributed on virtually every mammalian cell. Most cells and tissues co-express multiple subtypes of purinoceptor; thus,
Gever, J.L.
core  

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