Results 111 to 120 of about 29,186 (237)

Dorsal raphe tau pathology disrupts sleep‐wake orchestration and sleep architecture in a sex‐specific manner

Alzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract INTRODUCTION Sleep disturbances are frequent symptoms of Alzheimer's disease (AD), mirrored by early pathology in the dorsal raphe nucleus (DRN). Whether early DRN pathology can drive sleep disturbances, and the relative contributions of serotonin (5‐HT) and sex, has not been directly tested.
Louis J. Kolling, Ruixiang Wang, Gabriel S. Gaudencio, Jamie S. Fishbeyn, Thomas D. James, Suzanne M. Mason, Riley O. McCoy, Zhimin Song, Ian Pascal McConnell, Kylie Ziemke, Kasia M. Janik, Yu Xu, Gabrielle Bierlein‐De La Rosa, Shafa Ismail, Catherine Anne Marcinkiewcz   +14 more
wiley   +1 more source

Frequency‐ and Network‐Specific Changes in Functional Connectivity Reflect Pathophysiological Mechanisms across Parkinson's Disease Stages

Annals of Neurology, Volume 100, Issue 2, Page 319-333, August 2026.
Objective Parkinson's disease (PD) is increasingly conceptualized as a disorder of large‐scale brain networks, yet whether and how frequency‐specific functional connectivity reorganizes across stages remains poorly understood. In this study, we used high‐density electroencephalography (EEG) to characterize cortico‐cortical functional connectivity ...
Matteo Conti, Valentina D'Onofrio, Luca Lorenzon, Laura Ludovica Grassi, Davide Mascioli, Valerio Ferrari, Clara Simonetta, Sofia Pavan, Francesca Di Giuliano, Mariangela Pierantozzi, Tommaso Schirinzi, Diego Centonze, Maurizio Corbetta, Angelo Antonini, Alessandro Stefani, Andrea Guerra   +15 more
wiley   +1 more source

EEG Time-Frequency Clustering Reveals Spectral Signatures of Glutamatergic and Cholinergic Activities and Their Interrelations. [PDF]

Biomedicines
Vorobyov V, Deev A.
europepmc   +1 more source

A Field Tool for the Rapid Measurement of Mussel Valve Closure Strength as a Proxy for Condition

Aquatic Conservation: Marine and Freshwater Ecosystems, Volume 36, Issue 8, August 2026.
ABSTRACT Freshwater mussels (Unionida) are key to the health of many freshwater systems through the ecosystem functions and services they provide, yet their populations are declining across the globe. To address these declines with appropriate conservation actions, it is necessary to apply informative tools for measuring and monitoring mussel health ...
Daniel A. Cossey, Silvia Giorgia Signorini, Camilla Della Torre, George Palmer, Richard Boothroyd, David C. Aldridge   +5 more
wiley   +1 more source

Neurotransmitter-Mediated Signaling in Glioblastoma and Glial Tumors: Biology and Therapeutic Opportunities. [PDF]

Oncol Res
Tralongo P, Ballato M, Zuccalà V, Fiorentino V, Giordano W, Casili G, Bellinghieri F, Caruso G, Angileri FF, Fadda G, Martini M, Caffo M.   +11 more
europepmc   +1 more source

Heartfelt intervention: A role for PVN oxytocin neurons in the prediabetic heart

The Journal of Physiology, EarlyView.
Grace K. Nielsen, Reesa M. Wilcox, Han‐Jun Wang   +2 more
wiley   +1 more source

Valorization of Ficus carica Pruning Residues as Selective Botanical Insecticides: Optimized Furanocoumarin Extraction, Efficacy Against Neotropical Stink Bugs, and Mechanistic Insights via Molecular Docking

Archives of Insect Biochemistry and Physiology, Volume 122, Issue 4, August 2026.
Optimized extracts from Ficus carica pruning waste exhibit strong biological activity against major stink bug pests. Complementary in silico analyses suggest this efficacy relies on pest‐specific acetylcholinesterase inhibition, predicting a promising, pollinator‐safe alternative for sustainable agriculture.
Thais A. Almeida, Arley R. Páez, Lara T. M. Costa, Guy Smagghe, Yara M. Cardoso, Letícia M. Faria, Eugênio E. Oliveira, João Paulo V. Leite   +7 more
wiley   +1 more source

Nicotinic acetylcholine receptors in pain modulation. [PDF]

Front Pharmacol
Cheng J, Chang J, Li S.
europepmc   +1 more source

A Systematic Review on Disease‐Modifying Therapies in Parkinsonian Disorders

Clinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 357-374, August 2026.
Parkinsonian disorders, including Parkinson's disease, Lewy body dementia, multiple system atrophy, and progressive supranuclear palsy, are progressive neurodegenerative conditions with no treatment options to slow disease progression. This systematic review provides an overview of evidence of disease‐modifying therapies that have been evaluated in ...
Pepijn P.N.M. Eijsvogel, Lars M.G. Smits, Philip H.C. Kremer, Geert Jan Groeneveld   +3 more
wiley   +1 more source

Bidirectional Modulation of Beam Traversal Performance by Acetylcholine in the Cerebellar Nuclei. [PDF]

J Neurosci
Iosif CI, Drake RAR, Apps R, Bashir ZI, Pickford J.   +4 more
europepmc   +1 more source