Results 251 to 260 of about 31,317 (345)

Effect of some prostanoid receptor modulators on cholinergic and purinergic pathways in rat model of hemorrhagic cystitis: potential beneficial action of selexipag and alprostadil. [PDF]

Naunyn Schmiedebergs Arch Pharmacol
Gerges EM, Helmy MM, Daabees TT, Senbel AM.   +3 more
europepmc   +1 more source

Mechanistic insight into the cholinergic, muscarinic and antagonistic effects of Khat (Catha edulis) on native nicotinic acetylcholine receptors

Siddig İbrahim Abdelwahab, Heyam Mohamed Ali Sidahmed, Hassan Ahmad Alfaifi, Dina A. I. Albadawi, Amal Alzahrani   +4 more
openalex   +2 more sources

Control failure risk, resistance and enzymatic activity of neurotoxic insecticides in Brazilian populations of Leucoptera coffeella (Lepidoptera: Lyonetiidae)

Pest Management Science, Volume 82, Issue 6, Page 5757-5766, June 2026.
Bioassays of 36 Leucoptera coffeella populations revealed resistance to neurotoxic insecticides, control failures of ≤62.9% and enzyme activity variation, with particularly high GST and low AChE levels. Abstract Background Leucoptera coffeella is a key pest of coffee crops in Brazil, causing significant damage by mining coffee leaves.
Daianna P. Costa, Carlos G. da Cruz, Ryan F. S. e Silva, Liliane E. Visôtto, Jesús E. Gomez, Marisol Giraldo‐Jaramillo, Flávio L. Fernandes   +6 more
wiley   +1 more source

Neurotransmitter Dysregulation in Parkinson's Disease: Pathophysiological Insights and Therapeutic Perspectives. [PDF]

ACS Chem Neurosci
Aslan FS, Barut B, Ozturk S, Eyigurbuz T, Akyuz E.   +4 more
europepmc   +1 more source

Structural insights into the binding mode of the hypnotic drug vornorexant to orexin receptors

Acta Crystallographica Section F, Volume 82, Issue 6, Page 201-207, June 2026.
The crystal structure of the human orexin type 2 receptor–vornorexant complex (3.29 Å resolution) and orexin type 1 receptor docking revealed a conserved U‐shaped binding conformation, explaining the high affinity and balanced dual antagonism of this dual orexin receptor antagonist. The structural data validate the rational design that incorporated a 1,
Masashi Mima, Chiemi Mishima-Tsumagari, Mayumi Sakata-Sakuta, Ryo Iwaoka, Kunihiko Iwamoto   +4 more
wiley   +1 more source

Glial Cells in Behavioral and Psychological Symptoms of Alzheimer's Disease. [PDF]

Int J Mol Sci
Hasan I, Tang X, Xu J.
europepmc   +1 more source

Can Sodium Oxybate Mitigate the Symptoms of Schizophrenia? [PDF]

Curr Neuropharmacol
Mamelak M.
europepmc   +1 more source

Evaluation of the effect of biperiden (cholinergic muscarinic receptor antagonist) on ethanol self-administration in rats

Paola Palombo, Clarice Ribeiro Lira, Sara Emi Matos Mendes Ferreira Badaro, L.O.F. Teodoro, Fábio C. Cruz, José Carlos Fernandes Galduróz, Rodrigo M. Leão   +6 more
openalex   +1 more source

Bidirectional genetic and phenotypic links between smoking and striatal iron content involving dopaminergic and inflammatory pathways

Addiction, Volume 121, Issue 6, Page 1580-1593, June 2026.
Abstract Background and aims Tobacco smoking is a major risk factor for cardiovascular and lung diseases. A better understanding of its neurobiological underpinnings will benefit the prevention of smoking‐related illnesses and mortality. Previous studies link smoking to increased iron concentration in the striatum, a central component of the brain's ...
Olga Trofimova, Ilaria Iuliani, Sven Bergmann   +2 more
wiley   +1 more source