Results 281 to 290 of about 746,801 (362)
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Comparative behavioral and neurochemical activities of cholinergic antagonists in rats.

Journal of Pharmacology and Experimental Therapeutics, 1993
The comparative behavioral and neurochemical activities of the muscarinic cholinergic antagonists scopolamine, trihexyphenidyl and pirenzepine, and the nicotinic cholinergic antagonist mecamylamine were evaluated in rats. The three muscarinic antagonists,
F. Bymaster   +3 more
semanticscholar   +1 more source

Effects of nicotine on fixed-interval behavior and their modification by cholinergic antagonists.

Journal of Pharmacology and Experimental Therapeutics, 1970
The effects of nicotine were studied on operant responding maintained in rats by a fixed-interval 88-second schedule of water reinforcement. Nicotine was administered immediately prior to the experimental session in doses of 0.05 to 0.4 mg/kg s.c.
M. Stitzer, J. Morrison, E. Domino
semanticscholar   +1 more source

Functional sudomotor responses to cholinergic agonists and antagonists in the mouse.

Journal of the Autonomic Nervous System, 1995
J. Vilches, X. Navarro, E. Verdú
semanticscholar   +3 more sources

[Effects of cholinergic antagonists in stress].

Patologicheskaia fiziologiia i eksperimental'naia terapiia, 2007
Effects of methacine, hexamethonium and their combinations with neostigmine on activity of B-lymphocytes in various phases of immune response and development of stress ulcers induced in animals were studied. The drugs were found to modulate B-lymphocyte activity for 28 days and longer.
G I, Nezhinskaia   +2 more
openaire   +2 more sources

Effects of p-chlorophenylalanine and cholinergic antagonists on body temperature changes induced by the administration of morphine to nontolerant and morphine-tolerant rats.

Journal of Pharmacology and Experimental Therapeutics, 1972
Morphine-HCl (50 mg/kg s.c.) produced a fall in the rectal tenmperature of rats maintained in an ambient temperature of 20°C. The administratioin of p -chlorophenylalanine ( p -CPA, 320 mg/kg i.p.) 48 hours before the morphine injection prevented the ...
T. Oka, M. Nozaki, E. Hosoya
semanticscholar   +1 more source

Novel alkoxy-oxazolyl-tetrahydropyridine muscarinic cholinergic receptor antagonists

Psychopharmacology, 1995
The purpose of the present studies was to compare a novel series of alkoxy-oxazolyl-tetrahydropyridines (A-OXTPs) as muscarinic receptor antagonists. The affinity of these compounds for muscarinic receptors was determined by inhibition of [3H]pirenzepine to M1 receptors in hippocampus, [3H]QNB to M2 receptors in brainstem, and [3H]oxotremorine-M to ...
H E, Shannon   +4 more
openaire   +2 more sources

Aryldiazonium Salts as Antagonists at Cholinergic Muscarinic Receptors

Canadian Journal of Physiology and Pharmacology, 1974
A series of aryldiazonium salts were synthesized and tested for inhibitory activity on the longitudinal muscle of the guinea pig ileum. The most potent member of the series, benzenediazonium fluoborate (BDF) (at 10−4 M with incubation for 5 min), produced a dose ratio of 600 for acetylcholine (Ach), 58 for cis-2-methyl-4-trimethylammonium methyl-1,3 ...
D H, Ross, D J, Triggle
openaire   +2 more sources

Effects of selected muscarinic cholinergic antagonists on [3H]acetylcholine release from rat hippocampal slices.

Journal of Pharmacology and Experimental Therapeutics, 1988
A number of cholinergic muscarinic (M) agonists and antagonists were studied for their ability to enhance tritiated acetylcholine ([3H]ACh) release from electrically field-stimulated rat hippocampal slices.
R. Pohorecki, R. Head, E. F. Domino
semanticscholar   +1 more source

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