Results 291 to 300 of about 746,801 (362)

Amiloride is a cholinergic antagonist in the rabbit pancreas

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1984
The effect of amiloride on fluid and protein secretion in the isolated rabbit pancreas and on amylase secretion in rabbit pancreatic acini has been studied. Amiloride (1 mM) has no effect on the pancreatic fluid secretion either in a normal incubation medium (143 mM Na+), or in a medium containing only 25 mM Na+.
G A, Kuijpers, J J, De Pont, I G, Van Nooy, A M, Fleuren-Jakobs, S L, Bonting, J F, Rodrigues de Miranda   +5 more
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Cholinergic agonists and antagonists

1983
This chapter reviews the effects of the parasympathetic nervous system on the physiological properties of the cardiovascular system and the mechanisms by which these effects are produced. In the context of this background, the cardiovascular effects of agents that augment and antagonize parasympathetic nervous system activity will be discussed.
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Trifluoperazine and calcium antagonists accelerate cholinergic desensitization inAplysia neurons

Brain Research, 1985
The onset of desensitization of excitatory acetylcholine responses in isolated, voltage clamped Aplysia RB neurons to microperfused agonist was accelerated by trifluoperazine and the calcium antagonists SKF-525A and D-600. In the absence of these drugs the time course of desensitization is described as the sum of two exponentials plus a constant. All 3
N T, Slater, A F, Hall, D O, Carpenter
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Antagonists of cholinergic and serotonergic responses of Aplysia buccal muscle

Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology, 1994
Cholinergic and serotonergic receptors of Aplysia californica buccal muscles were characterized pharmacologically by determining compounds that effectively inhibited contractile responses to acetylcholine (ACh) and modulatory effects of serotonin (5-HT), respectively. pA50 for ACh to elicit contraction averaged 4.7 +/- 0.1 (mean +/- SE, equivalent to 2
J L, Ram, K, Judge, M A, Jednak
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Bovine pancreatic polypeptide as an antagonist of muscarinic cholinergic receptors

American Journal of Physiology-Gastrointestinal and Liver Physiology, 1987
In dispersed acini from rat pancreas, it was found that bovine pancreatic polypeptide (BPP) and its C-fragment hexapeptide amide (PP-6), at concentrations of 0.1 and 30 microM, respectively, could significantly inhibit amylase secretion stimulated by carbachol (P less than 0.01 or 0.05, respectively), and this inhibition by BPP was dose dependent ...
G Z, Pan, L, Lu, J M, Qian, B G, Xue
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AGONIST‐ANTAGONIST INTERACTION AT THE CHOLINERGIC RECEPTOR OF DENERVATED DIAPHRAGM

Australian Journal of Experimental Biology and Medical Science, 1972
SummaryA study has been made of the cholinergic receptor induced by chronic denervation in the rat diaphragm. The agonists acetylcholine, carbachol and tetramethylammonium produced a dose‐dependent contraction of the denervated diaphragm. These agonists also brought about a graded depolarization of the muscle cells.
S E, Freeman, R J, Turner
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Ligand specificity of state transitions in the cholinergic receptor: behavior of agonists and antagonists.

Molecular Pharmacology, 1979
Several cholinergic ligands, including a series of methylene-linked bisquaternary ammonium compounds, have been examined for their ability to induce a state transition in the membrane-associated cholinergic receptor where there is a slow increase in ...
Gregory Weiland, P. Taylor
semanticscholar   +1 more source

Effects of cholinergic agonists and antagonists on morphine-withdrawal syndrome

Psychopharmacology, 1976
The effects of pilocarpine, atropine and dexetimide were studied on the occurrence and intensity of morphine-withdrawal signs observed after cessation of chronic morphine injections. Pilocarpine was effective in reducing both 'wet-dog' like body shakes and aggression but it increased diarrhea and weight loss.
M D, Hynes, G, Gianutsos, H, Lal
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Naloxone modulates the behavioral effects of cholinergic agonists and antagonists

Psychopharmacology, 1991
Peripheral glucose administration enhances memory in rodents and humans. Recent findings suggest that glucose may affect behavior, in part, by augmenting central cholinergic functions and by attenuating central opiate functions. The present experiments examined interactions between an opiate antagonist, naloxone, and cholinergic agents to determine ...
D L, Walker, T, McGlynn, C, Grey, M, Ragozzino, P E, Gold   +4 more
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VIP antagonists enhance excitatory cholinergic neurotransmission in the human airway

Lung, 1994
It has been reported that a low concentration of exogenously applied vasoactive intestinal peptide (VIP) suppresses the release of acetylcholine (ACh) from vagus nerve terminals in the ferret and feline trachea. There has been, however, no documentation of the prejunctional action of VIP in the human airway.
H, Aizawa, H, Inoue, M, Shigyo, S, Takata, H, Koto, K, Matsumoto, N, Hara   +6 more
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