Results 61 to 70 of about 31,317 (345)

Cholinergic agonist-antagonist interactions on neocortical and limbic EEG activation [PDF]

, 1967
The effects of various cholinergic agonists and antagonists and their interactions were determined on the awake-sleep cycle of cats with chronic indwelling brain electrodes.
Kjen-Ichi Yamamoto,, Domino, Edward F.
core   +1 more source

Prescribing trends of glaucoma drugs in six major cities of China from 2013 to 2017.

PLoS ONE, 2020
ObjectiveTo evaluate the prescribing trends of glaucoma drugs in six major cities of China from 2013 to 2017.MethodsA descriptive analysis using pharmacy prescription data was conducted.
Lingyan Yu, Kai Ding, Lifang Luo, Zhenwei Yu   +3 more
doaj   +1 more source

Long-term results of oxybutynin use in treating facial hyperhidrosis [PDF]

Anais Brasileiros de Dermatologia, 2014
BACKGROUND: Facial hyperhidrosis can lead to serious emotional distress. Video-assisted thoracic sympathectomy resolves symptoms effectively, though it may be associated with compensatory hyperhidrosis, which may be more common in patients undergoing ...
Nelson Wolosker, Marcelo Passos Teivelis, Mariana Krutman, Taiz Pereira Dozono de Almeida Campbell, Paulo Kauffman, José Ribas de Campos, Pedro Puech-Leão   +6 more
doaj   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Responses of pigeon vestibular hair cells to cholinergic agonists and antagonists [PDF]

Brain Research, 2011
Acetylcholine (ACh) is the major neurotransmitter released from vestibular efferent terminals onto hair cells and afferents. Previous studies indicate that the two classes of acetylcholine receptors, nicotinic (nAChRs) and muscarinic receptors (mAChRs), are expressed by vestibular hair cells (VHCs).
Gang Q, Li, Manning J, Correia
openaire   +2 more sources

Neonatal seizures and GABAergic drugs: Scylla and Charybdis?

Epilepsia Open, EarlyView.
Abstract Neonates have a high incidence of seizures that are frequently difficult to control with conventional first‐line anti‐seizure medications, which are gamma‐aminobutyric acid (GABA) agonists. The reasons for this clinical problem are multifold but are likely related to the unique physiology of the immature nervous system. Specifically, the early
Kerry W. Thompson, Lucie Suchomelova, Claude G. Wasterlain   +2 more
wiley   +1 more source

Dissociable contributions of mediodorsal and anterior thalamic nuclei in visual attentional performance: A comparison using nicotinic and muscarinic cholinergic receptor antagonists [PDF]

, 2020
Background: Thalamic subregions mediate various cognitive functions, including attention, inhibitory response control and decision making. Such neuronal activity is modulated by cholinergic thalamic afferents and deterioration of such modulatory ...
Pienaar, Ilse, Mantanona, Craig, Božič, Tadej, Tadej Božic (16281431), Yogita Chudasama (9560391), Robbins, Trevor W, Ilse Pienaar (4504357), Jeffrey W Dalley (9560394), Trevor W Robbins (8414619), Pienaar, Ilse S, Dalley, Jeffrey W, Craig P Mantanona (9560385), Mantanona, Craig P, Johan Alsiö (177218), Alsiö, Johan, Chudasama, Yogita   +15 more
core   +2 more sources

Pinnatoxins’ Deleterious Effects on Cholinergic Networks: From Experimental Models to Human Health

Marine Drugs, 2019
Pinnatoxins (PnTXs) are emerging neurotoxins that were discovered about 30 years ago. They are solely produced by the marine dinoflagellate Vulcanodinium rugosum, and may be transferred into the food chain, as they have been found in various marine ...
Nicolas Delcourt, Emmeline Lagrange, Eric Abadie, Valérie Fessard, Jean-Marc Frémy, Jean-Paul Vernoux, Marie-Bénédicte Peyrat, Thomas Maignien, Nathalie Arnich, Jordi Molgó, César Mattei   +10 more
doaj   +1 more source

Brain–Computer Interfaces: The Dawn of a New Era in Disease Treatment

Exploration, EarlyView.
This study investigates the potential of brain–computer interface (BCI) technology in treating neuropsychiatric disorders, such as movement and communication barriers. Our review examines the history, signal paradigms, and diverse applications of BCI while also discussing ongoing research into novel materials and emerging technologies that offer ...
Yuqi Feng, Wangzheqi Zhang, Jun Chen, Huang Wu, Lei Wu, Yanhao Qiu, Xiaoming Deng, Chenglong Zhu, Yisheng Chen, Zhijie Zhao, Changli Wang, Xiaomin Zhang   +11 more
wiley   +1 more source

Physiological functions of the cholinergic system in immune cells

Journal of Pharmacological Sciences, 2017
T and B cells, macrophages and dendritic cells (DCs) all express most of the components necessary for a functional cholinergic system. This includes choline acetyltransferase (ChAT), muscarinic and nicotinic acetylcholine (ACh) receptors (mAChRs and ...
Takeshi Fujii, Masato Mashimo, Yasuhiro Moriwaki, Hidemi Misawa, Shiro Ono, Kazuhide Horiguchi, Koichiro Kawashima   +6 more
doaj   +1 more source