Results 51 to 60 of about 176,034 (239)

Co‐activation of Selective Nicotinic Acetylcholine Receptor Subtypes Is Required for Neuroprotection against Alzheimer's Disease

Advanced Science, EarlyView.
ABSTRACT Beta‐amyloid peptide (Aβ)‐induced suppression of hippocampal GABAergic interneuron activity drives hyperexcitability, amyloid pathology, and cognitive impairment in Alzheimer's disease (AD), suggesting that enhancing hippocampal inhibition may be protective.
Rahmi Lee, Gayeon Kim, Ellison R. Black, Seonil Kim   +3 more
wiley   +1 more source

Linking actions to outcomes : the role of the posterior pedunculopontine tegmental nucleus in instrumental learning [PDF]

, 2012
Located in the mesopontine tegmentum, the pedunculopontine tegmental nucleus (PPTg) is comprised principally of glutamatergic, cholinergic and GABAergic neurons.
MacLaren, Duncan A. A.
core   +2 more sources

Sudden death in strabismus surgery under local anaesthesia: a case report [PDF]

Journal of Emergency Practice and Trauma, 2017
Oculocardiac reflex (OCR) sometimes occurs as a result of pressure on the eye or traction of the intraorbital surrounding structures during ophthalmic surgery. This can result in bradycardiac arrhythmia and cardiac arrest.
Mahesh Chand Meena, Kuldeep Panchal, Mukta Rani   +2 more
doaj   +1 more source

Autonomic Nerve Fiber Compositions of Zygomaticotemporal and Lacrimal Nerves: A Cadaveric Immunohistochemical Analysis

International Forum of Allergy &Rhinology, EarlyView.
Key Points Zygomaticotemporal (ZTN) and lacrimal nerves (LN) both carried sympathetics and parasympathetics ZTNs had more parasympathetics than LNs, but markers varied significantly within and between nerves LN parasympathetics to the lacrimal gland may mitigate dry eye after vidian ...
Bushra Rahman, Hangil Lee, Kelly A. Shaftel, Abdurrahman Abdurrob, Yusra Mansour, Swapna Vemuri, Jun Jin, Jack P. Rock, John R. Craig   +8 more
wiley   +1 more source

Cholinergic interneurons mediate fast VGluT3-dependent glutamatergic transmission in the striatum.

PLoS ONE, 2011
The neurotransmitter glutamate is released by excitatory projection neurons throughout the brain. However, non-glutamatergic cells, including cholinergic and monoaminergic neurons, express markers that suggest that they are also capable of vesicular ...
Michael J Higley, Aryn H Gittis, Ian A Oldenburg, Nina Balthasar, Rebecca P Seal, Robert H Edwards, Bradford B Lowell, Anatol C Kreitzer, Bernardo L Sabatini   +8 more
doaj   +1 more source

Hippocampus and Entorhinal Cortex Recruit Cholinergic and NMDA Receptors Separately to Generate Hippocampal Theta Oscillations

Cell Reports, 2017
Summary: Although much progress has been made in understanding type II theta rhythm generation under urethane anesthesia, less is known about the mechanisms underlying type I theta generation during active exploration.
Zhenglin Gu, Georgia M. Alexander, Serena M. Dudek, Jerrel L. Yakel   +3 more
doaj   +1 more source

Prescribing trends of glaucoma drugs in six major cities of China from 2013 to 2017.

PLoS ONE, 2020
ObjectiveTo evaluate the prescribing trends of glaucoma drugs in six major cities of China from 2013 to 2017.MethodsA descriptive analysis using pharmacy prescription data was conducted.
Lingyan Yu, Kai Ding, Lifang Luo, Zhenwei Yu   +3 more
doaj   +1 more source

Long-term results of oxybutynin use in treating facial hyperhidrosis [PDF]

Anais Brasileiros de Dermatologia, 2014
BACKGROUND: Facial hyperhidrosis can lead to serious emotional distress. Video-assisted thoracic sympathectomy resolves symptoms effectively, though it may be associated with compensatory hyperhidrosis, which may be more common in patients undergoing ...
Nelson Wolosker, Marcelo Passos Teivelis, Mariana Krutman, Taiz Pereira Dozono de Almeida Campbell, Paulo Kauffman, José Ribas de Campos, Pedro Puech-Leão   +6 more
doaj   +1 more source

Adipose‐derived mesenchymal stem cell injection into the KI10 acupoint mitigates cartilage damage in KOA rats through PGE2‐mediated α7nAChR/NF‐κB pathway

Animal Models and Experimental Medicine, EarlyView.
In our research, KOA rat models were established and treated with ADSC injection into the KI10 acupoint. Pain relief, behavioral function, and joint structural improvements were systematically assessed using ethological tests, imaging, histopathological staining, transmission electron microscopy, and molecular analyses.
Mengwei Dong, Wenfang Li, Wanpeng Yang, Te Ba, Nan Nan, Yang Liu, Jing Han, Huiqin Hao   +7 more
wiley   +1 more source

Reframing the Gut–Brain Axis: The Gut Wall as a Neural Immune Interface in Multiple Sclerosis and Autoimmune Neurological Diseases

Annals of Neurology, EarlyView.
Gut wall physiology in multiple sclerosis (MS) and autoimmune neurologic diseases remains underexplored but may span gut barrier dysfunction, enteric glial targeting, mucosal immune dysregulation, and autoimmune targets within the enteric nervous system (ENS).
Federico Montini, Sean J. Pittock, Laura Cacciaguerra, Howard L. Weiner, Luke A. Schwerdtfeger   +4 more
wiley   +1 more source