A Cholinergic Synaptically Triggered Event Participates in the Generation of Persistent Activity Necessary for Eye Fixation [PDF]
An exciting topic regarding integrative properties of the nervous system is how transient motor commands or brief sensory stimuli are able to evoke persistent neuronal changes, mainly as a sustained, tonic action potential firing.
Alvarado, JC+5 more
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Cholinergic and Glutamatergic Axons Differentially Require Glial Support in the Drosophila PNS. [PDF]
Main Points In the Drosophila PNS, motor‐ and sensory axons differentially interact with wrapping glia processes. Sensory axons are more weakly associated with wrapping glia and show a length dependent degeneration upon loss of wrapping glia. ABSTRACT In vertebrates, there is a differential interaction between peripheral axons and their associated ...
Kautzmann S, Rey S, Krebs A, Klämbt C.
europepmc +2 more sources
Activity of nAChRs containing α9 subunits modulates synapse stabilization via bidirectional signaling programs [PDF]
Although the synaptogenic program for cholinergic synapses of the neuromuscular junction is well known, little is known of the identity or dynamic expression patterns of proteins involved in non-neuromuscular nicotinic synapse development.
Elgoyhen, Ana Belen+3 more
core +1 more source
Decoding Gastric Reflexes: The Role of Mechanosensitive Enteric Neurons in Stomach Motility. [PDF]
ABSTRACT This review focuses on mechanosensitive enteric neurons (MEN) in the guinea pig stomach and their roles in gastric motor reflex pathways. The guinea pig model is advantageous for studying gastric physiology, as its stomach structure and function closely resemble those of humans. Gastric motility involves distinct functional regions: the fundus
Mazzuoli-Weber G, Mayr S, Elfers K.
europepmc +2 more sources
Short-term synaptic plasticity regulates the level of olivocochlear inhibition to auditory hair cells [PDF]
In the mammalian inner ear, the gain control of auditory inputs is exerted by medial olivocochlear (MOC) neurons that innervate cochlear outer hair cells (OHCs).
Ballestero, Jimena Andrea+5 more
core +1 more source
Optogenetic stimulation of the brainstem dorsal motor nucleus ameliorates acute pancreatitis
IntroductionInflammation is an inherently self-amplifying process, resulting in progressive tissue damage when unresolved. A brake on this positive feedback system is provided by the nervous system which has evolved to detect inflammatory signals and ...
Dane A. Thompson+21 more
doaj +1 more source
Changes in murine anorectum signaling across the life course [PDF]
Background: Increasing age is associated with an increase in the incidence of chronic constipation and fecal impaction. The contribution of the natural aging process to these conditions is not fully understood.
Fidalgo, S.+4 more
core +4 more sources
The retrosplenial cortex (RSC) receives cholinergic afferent fibers from the medial septal nucleus and diagonal band of Broca (DBB) by way of the cingulate bundle and the fornix.
Ying J. Li, Walter C. Low Ph.D.
doaj +1 more source
Modulation of Hippocampal Circuits by Muscarinic and Nicotinic Receptors
This article provides a review of the effects of activation of muscarinic and nicotinic receptors on the physiological properties of circuits in the hippocampal formation.
Holger Dannenberg+2 more
doaj +1 more source
BMP9 protects septal neurons from axotomy-evoked loss of cholinergic phenotype. [PDF]
Cholinergic projection from the septum to the hippocampus is crucial for normal cognitive function and degeneration of cells and nerve fibers within the septohippocampal pathway contributes to the pathophysiology of Alzheimer's disease.
Ignacio Lopez-Coviella+3 more
doaj +1 more source